HK1080514A1 - Detection of biological molecules by differential partitioning of enzyme substrates and products - Google Patents

Detection of biological molecules by differential partitioning of enzyme substrates and products

Info

Publication number
HK1080514A1
HK1080514A1 HK05111502A HK05111502A HK1080514A1 HK 1080514 A1 HK1080514 A1 HK 1080514A1 HK 05111502 A HK05111502 A HK 05111502A HK 05111502 A HK05111502 A HK 05111502A HK 1080514 A1 HK1080514 A1 HK 1080514A1
Authority
HK
Hong Kong
Prior art keywords
enzyme
sample
partitioning
products
detection
Prior art date
Application number
HK05111502A
Other languages
English (en)
Inventor
R Stephen Brown
Samir P Tabash
Igor S Kozin
Eric J-P Marcotte
Arthur N Ley
Kevin R Hall
Moe Hussain
Peter V Hodson
Parveen Akhtar
Marseille John G St
Robin A Wynne-Edwards
Raymond J Bowers
Original Assignee
Univ Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kingston filed Critical Univ Kingston
Publication of HK1080514A1 publication Critical patent/HK1080514A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK05111502A 2002-09-20 2005-12-14 Detection of biological molecules by differential partitioning of enzyme substrates and products HK1080514A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41201502P 2002-09-20 2002-09-20
PCT/CA2003/001439 WO2004027084A1 (en) 2002-09-20 2003-09-22 Detection of biological molecules by differential partitioning of enzyme substrates and products

Publications (1)

Publication Number Publication Date
HK1080514A1 true HK1080514A1 (en) 2006-04-28

Family

ID=32030780

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05111502A HK1080514A1 (en) 2002-09-20 2005-12-14 Detection of biological molecules by differential partitioning of enzyme substrates and products

Country Status (11)

Country Link
US (4) US7402426B2 (xx)
EP (1) EP1539986B1 (xx)
JP (2) JP4857434B2 (xx)
AT (1) ATE367449T1 (xx)
AU (1) AU2003266899B2 (xx)
CA (1) CA2497555C (xx)
DE (1) DE60315043T2 (xx)
ES (1) ES2290487T3 (xx)
HK (1) HK1080514A1 (xx)
MX (1) MXPA05003068A (xx)
WO (1) WO2004027084A1 (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4857434B2 (ja) 2002-09-20 2012-01-18 クィーンズ ユニバーシティー アット キングストン 酵素基質および酵素生成物の分配差による生体分子の検出
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
WO2006116455A2 (en) 2005-04-26 2006-11-02 Applera Corporation System for genetic surveillance and analysis
EP1926825A4 (en) * 2005-09-20 2008-09-24 Univ Arizona State METHODS FOR DETECTING AND CHARACTERIZING MICROORGANISMS
WO2007095060A2 (en) * 2006-02-13 2007-08-23 Thermo Electron Scientific Instruments Llc Spectrometric measurements during blending/mixing
JP5374809B2 (ja) * 2006-06-29 2013-12-25 パナソニック株式会社 微生物計測システム
US10213164B2 (en) 2008-09-26 2019-02-26 Qualcomm Incorporated Method and apparatus for under-sampled acquisition and transmission of photoplethysmograph (PPG) data and reconstruction of full band PPG data at the receiver
WO2010101931A2 (en) 2009-03-03 2010-09-10 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
US10006075B2 (en) 2009-05-15 2018-06-26 Biomerieux, Inc. Automated loading mechanism for microbial detection apparatus
JP2012526996A (ja) 2009-05-15 2012-11-01 ビオメリュー・インコーポレイテッド 試料内の微生物因子の迅速な同定および／または特徴付けのためのシステムおよび方法
US8891086B2 (en) 2009-06-15 2014-11-18 Thermo Scientific Portable Analytical Instruments Inc. Optical scanning systems and methods for measuring a sealed container with a layer for reducing diffusive scattering
FR2949560A1 (fr) * 2009-09-02 2011-03-04 Centre Nat Rech Scient Systeme de spectroscopie a guide d'onde pour l'analyse de particules dans un milieu
EP2516666B1 (en) 2009-12-22 2016-04-20 3M Innovative Properties Company Methods of detecting microorganisms and kits therefore
EP2582784A4 (en) * 2010-06-18 2014-01-01 Pathogen Detection Systems Inc OPTICAL SYSTEM FOR DETECTING PATHOGEN AGENT AND QUALITY CONTROL MATERIALS FOR USE IN THE SAME
WO2011156915A2 (en) * 2010-06-18 2011-12-22 Pathogen Detection Systems, Inc. Method and system for detecting biological molecules in samples
JP5621846B2 (ja) * 2010-06-21 2014-11-12 コニカミノルタ株式会社 蛍光測定方法
CN103189524B (zh) 2010-11-01 2015-01-28 3M创新有限公司 生物灭菌指示器及其使用方法
JP5934231B2 (ja) 2010-11-01 2016-06-15 スリーエム イノベイティブ プロパティズ カンパニー 生物学的滅菌インジケーター
EP3269822B1 (en) * 2010-11-24 2019-11-27 3M Innovative Properties Company Methods to detect a biological activity
WO2013056720A1 (en) 2011-10-18 2013-04-25 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Fluorescent dyes with phosphorylated hydroxymethyl groups and their use in light microscopy and imaging techniques
KR101343353B1 (ko) 2012-05-04 2013-12-20 한국과학기술연구원 엔테로박터 및 에스케리키아의 구별 방법
CA2894462A1 (en) * 2012-12-14 2014-06-19 Bryan LARSON Dual medicament carpule for dental syringes
US9850515B2 (en) 2013-02-08 2017-12-26 Bio-Rad Laboratories, Inc. Affinity-based partition assay for detection of target molecules
CN104034705B (zh) * 2013-03-06 2017-05-10 常州欣宏科生物化学有限公司 一种荧光探针检测酶活性方法
JP6567274B2 (ja) * 2014-12-10 2019-08-28 水ｉｎｇ株式会社 分離膜の汚染状態分析方法、その方法を用いるろ過対象水の水質評価方法
EP3332243B1 (en) * 2015-08-03 2024-05-01 YSI, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
US11656180B2 (en) 2015-08-03 2023-05-23 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
JP2021525894A (ja) * 2018-06-01 2021-09-27 オーブ エックスワイゼット， インコーポレイテッド 媒体中の検体の検出
CN110763823B (zh) * 2019-11-22 2022-04-12 威海精讯畅通电子科技有限公司 一种手持式土壤快速检测仪及检测方法
CN114428070B (zh) * 2021-12-28 2024-05-17 南京师范大学 一种检测革兰氏阴性菌的分子印迹荧光纳米粒子及其制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2856251A1 (de) * 1978-12-27 1980-07-17 Max Planck Gesellschaft Fuellungen fuer indikatorraeume
GB2078370A (en) 1980-06-13 1982-01-06 Nat Res Dev Binding assays
DK256581A (da) * 1980-06-13 1981-12-14 Nat Res Dev Bindingsanalyse
AT377095B (de) * 1982-11-23 1985-02-11 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe sowie verfahren zur herstellung desselben
US5238809A (en) * 1986-02-03 1993-08-24 Avl Medical Instruments Ag Method for optical determination of the catalytic enzyme activity and arrangement for implementing this method
AT392539B (de) * 1986-02-03 1991-04-25 Avl Verbrennungskraft Messtech Verfahren zur optischen bestimmung der katalytischen enzymaktivitaet einer probe, und eine anordnung zur durchfuehrung des verfahrens
JPS62203047A (ja) * 1986-02-28 1987-09-07 Advance:Kk アンモニアセンサ−
US4712865A (en) * 1987-01-05 1987-12-15 Baxter Travenol Laboratories Dye containing silicon polymer composition
JPH0814541B2 (ja) * 1987-04-03 1996-02-14 ティーディーケイ株式会社 光フアイバ−センサ−
JPS6463842A (en) * 1987-09-03 1989-03-09 Terumo Corp Method and apparatus for measuring concentration of optical material
US4974929A (en) * 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
FR2650076B1 (fr) * 1989-07-20 1991-10-04 Commissariat Energie Atomique Capteur chimique actif a fibre optique et son procede de fabrication
JP3065639B2 (ja) 1990-08-22 2000-07-17 三菱電線工業株式会社 ケーブル事故検出装置
US5376551A (en) * 1991-03-12 1994-12-27 University Of Utah Research Foundation Apparatus for using fluorescently labeled ligands in studying interaction of a native ligand and its receptor
WO1992016648A1 (en) * 1991-03-18 1992-10-01 Environmental Test Systems, Inc. Chemiluminescent test for microorganisms
JP3048672B2 (ja) * 1991-04-30 2000-06-05 栄研化学株式会社 試薬結合ポリマー、該ポリマー膜および該ポリマーを含む担持体
GB9116909D0 (en) 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
GB9215973D0 (en) * 1992-07-28 1992-09-09 Univ Manchester Sensor devices
US5364767A (en) * 1993-02-11 1994-11-15 Research Organics, In. Chromogenic compounds and methods of using same
GB9315183D0 (en) * 1993-07-22 1993-09-08 British Nuclear Fuels Plc Biosensors
JPH07147997A (ja) * 1993-11-26 1995-06-13 Apere:Kk 微生物検査方法および微生物検査装置
KR970707302A (ko) * 1994-11-07 1997-12-01 프랭크 파렌트 대장균군 또는 대장균을 검출하기 위한 효소적 방법(enzymatic method for detecting coliform bacteria or e. coli)
EP0853658B1 (en) * 1995-09-29 2000-11-22 Idexx Laboratories, Inc. Self-contained incubator for growth of microorganism
WO1997019188A1 (en) * 1995-11-22 1997-05-29 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
JPH09152433A (ja) * 1995-11-30 1997-06-10 Aisin Seiki Co Ltd 固相担体に固定した核酸等の検出方法
US5972595A (en) * 1997-12-19 1999-10-26 Nen Life Science Products, Inc. Enzyme assay using a solid phase substrate
US6372895B1 (en) * 2000-07-07 2002-04-16 3M Innovative Properties Company Fluorogenic compounds
EP1335200A4 (en) 2000-05-11 2004-03-24 Matsushita Ecology Sys Co CHEMICAL SENSOR DEVICE
AU2002250295A1 (en) * 2001-03-16 2002-10-03 Ewatertek Inc. System and method for monitoring water quality and transmitting water quality data
EP1519678A2 (en) * 2001-10-02 2005-04-06 Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California Internal biochemical sensing device
EP1453591A4 (en) * 2001-12-06 2006-03-08 Purdue Research Foundation MESOPOROUS MEMBRANE COLLECTOR AND SEPARATOR FOR DETECTING PATHOGENIC AGENTS IN AIR SUSPENSION
WO2003087783A1 (en) * 2002-04-05 2003-10-23 Powerzyme, Inc. Analyte sensor
US20040047535A1 (en) * 2002-09-09 2004-03-11 Ljerka Ukrainczyk Enhanced fiber-optic sensor
JP4857434B2 (ja) 2002-09-20 2012-01-18 クィーンズ ユニバーシティー アット キングストン 酵素基質および酵素生成物の分配差による生体分子の検出

Also Published As

Publication number Publication date
EP1539986A1 (en) 2005-06-15
US8377686B2 (en) 2013-02-19
JP4857434B2 (ja) 2012-01-18
DE60315043D1 (de) 2007-08-30
DE60315043T2 (de) 2008-04-10
WO2004027084A1 (en) 2004-04-01
AU2003266899A1 (en) 2004-04-08
US20140295403A1 (en) 2014-10-02
CA2497555A1 (en) 2004-04-01
JP2011254816A (ja) 2011-12-22
ATE367449T1 (de) 2007-08-15
US20130217041A1 (en) 2013-08-22
US20040106164A1 (en) 2004-06-03
ES2290487T3 (es) 2008-02-16
EP1539986B1 (en) 2007-07-18
CA2497555C (en) 2013-06-11
JP5799353B2 (ja) 2015-10-21
AU2003266899B2 (en) 2008-02-28
JP2005538728A (ja) 2005-12-22
MXPA05003068A (es) 2005-06-08
US8632966B2 (en) 2014-01-21
US20090117600A1 (en) 2009-05-07
US7402426B2 (en) 2008-07-22

Similar Documents

Publication Publication Date Title
HK1080514A1 (en) Detection of biological molecules by differential partitioning of enzyme substrates and products
Hobson et al. Microbial detection
US7939285B2 (en) Filtration method for detecting microbial contamination
GB2438139A (en) A method of detecting and identifying bacteria
EP0542790A4 (xx)
Zheng et al. Detection of dichlorvos residue by flow injection calorimetric biosensor based on immobilized chicken liver esterase
Inoue et al. Electrochemical detection of endotoxin using recombinant factor C zymogen
JP2007525227A5 (xx)
DE60208809D1 (de) Enzymsubstrate zum Nachweis der beta-D-ribofuranosidase Aktivität
WO2006091630A3 (en) Determination of viable microorganisms using coated paramagnetic beads
Wang et al. Characterization of bacterial community and flavor differences of different types of Douchi
Lapa et al. Development of a sequential injection analysis system for the simultaneous biosensing of glucose and ethanol in bioreactor fermentation
DE69932447D1 (de) Auf sporenauskeimung basierendes analytisches system
WO2008009046A8 (en) Detection of enzymes and microorganisms and devices therefor
AU2002221988A1 (en) Method and medium for detecting/identifying micro-organisms with esterase activity
CN103852456A (zh) 一种实时恒温定量快速检测铅的设备及方法
Kuusk et al. Transient phase calibration of tyrosinase-based carbaryl biosensor
Soldatkin et al. Optimization of enzymatic bioselective elements as components of potentiometric multibiosensor
Deshpande et al. Recent advances in bioanalytical techniques using enzymatic assay
WO2004016802A3 (en) Methods and apparatus for preparing and assaying biological samples to determine protein concentration
Arruda et al. Simple and inexpensive flow L-glutamate determination using pumpkin tissue
WO2004094653A3 (en) Differential tag length analysis of cell proliferation
Aaron et al. The analyses of fungicides, herbicides and insecticides
Sharma et al. Biosensors for Monitoring Contaminants in Milk and Milk Products
WO2013140210A1 (en) Identification of cellulolytic microorganism contamination in food and other materials

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20230921