HK1079764A1 - Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative - Google Patents
Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivativeInfo
- Publication number
- HK1079764A1 HK1079764A1 HK05111846A HK05111846A HK1079764A1 HK 1079764 A1 HK1079764 A1 HK 1079764A1 HK 05111846 A HK05111846 A HK 05111846A HK 05111846 A HK05111846 A HK 05111846A HK 1079764 A1 HK1079764 A1 HK 1079764A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- derivative
- production
- amino acid
- pharmaceutical compositions
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/10—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
- C07D213/34—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/14—Benz[f]indenes; Hydrogenated benz[f]indenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/28—Phenalenes; Hydrogenated phenalenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0202199A FR2836143B1 (fr) | 2002-02-21 | 2002-02-21 | Nouveaux derives d'acides amines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR2003/000506 WO2003070690A2 (fr) | 2002-02-21 | 2003-02-17 | Nouveaux derives d'acides amines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1079764A1 true HK1079764A1 (en) | 2006-04-13 |
Family
ID=27636380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05111846A HK1079764A1 (en) | 2002-02-21 | 2005-12-22 | Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative |
Country Status (21)
Country | Link |
---|---|
US (1) | US7265220B2 (fr) |
EP (1) | EP1476421A2 (fr) |
JP (1) | JP4106337B2 (fr) |
KR (1) | KR100668194B1 (fr) |
CN (1) | CN1257889C (fr) |
AR (1) | AR038443A1 (fr) |
AU (1) | AU2003224198A1 (fr) |
BR (1) | BR0307776A (fr) |
CA (1) | CA2474785A1 (fr) |
EA (1) | EA006389B1 (fr) |
FR (1) | FR2836143B1 (fr) |
GE (1) | GEP20074100B (fr) |
HK (1) | HK1079764A1 (fr) |
MA (1) | MA27110A1 (fr) |
MX (1) | MXPA04007988A (fr) |
NO (1) | NO20043910L (fr) |
NZ (1) | NZ534359A (fr) |
PL (1) | PL370817A1 (fr) |
UA (1) | UA77763C2 (fr) |
WO (1) | WO2003070690A2 (fr) |
ZA (1) | ZA200406027B (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7592461B2 (en) * | 2005-12-21 | 2009-09-22 | Bristol-Myers Squibb Company | Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
GB0807828D0 (en) * | 2008-04-29 | 2008-06-04 | Vantia Ltd | Aminopyridine derivatives |
US9290485B2 (en) * | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
GB201322091D0 (en) | 2013-12-13 | 2014-01-29 | Cambridge Entpr Ltd | Modified serpins for the treatment of bleeding disorders |
EP3749697A4 (fr) | 2018-02-05 | 2021-11-03 | Bio-Rad Laboratories, Inc. | Résine de chromatographie ayant un ligand mode mixte échange anionique/hydrophobe |
WO2020092139A1 (fr) * | 2018-10-29 | 2020-05-07 | Huahai Us Inc. | Nouveaux composés dipeptidiques et leurs utilisations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2128186C1 (ru) | 1993-04-28 | 1999-03-27 | Кумиай Кемикал Индастри Ко., Лтд. | Производные амидов аминокислот, способ получения, фунгицидная композиция для сельского хозяйства и садоводства |
EP1007078A4 (fr) * | 1996-11-19 | 2002-11-13 | Saulius Butenas | Peptidomimetiques contenant des fractions de 6-peptidylamino-1-naphtalenesulfonamide |
US6358960B1 (en) * | 1998-02-17 | 2002-03-19 | Ono Pharmaceutical Co., Ltd. | Amidino derivatives and drugs containing the same as the active ingredient |
-
2002
- 2002-02-21 FR FR0202199A patent/FR2836143B1/fr not_active Expired - Fee Related
-
2003
- 2003-02-17 CN CNB038041189A patent/CN1257889C/zh not_active Expired - Fee Related
- 2003-02-17 AU AU2003224198A patent/AU2003224198A1/en not_active Abandoned
- 2003-02-17 MX MXPA04007988A patent/MXPA04007988A/es active IP Right Grant
- 2003-02-17 JP JP2003569599A patent/JP4106337B2/ja not_active Expired - Fee Related
- 2003-02-17 US US10/505,005 patent/US7265220B2/en not_active Expired - Fee Related
- 2003-02-17 KR KR1020047013041A patent/KR100668194B1/ko not_active IP Right Cessation
- 2003-02-17 BR BR0307776-4A patent/BR0307776A/pt not_active IP Right Cessation
- 2003-02-17 WO PCT/FR2003/000506 patent/WO2003070690A2/fr active IP Right Grant
- 2003-02-17 GE GEAP8409A patent/GEP20074100B/en unknown
- 2003-02-17 EA EA200401011A patent/EA006389B1/ru not_active IP Right Cessation
- 2003-02-17 NZ NZ534359A patent/NZ534359A/en unknown
- 2003-02-17 PL PL03370817A patent/PL370817A1/xx not_active Application Discontinuation
- 2003-02-17 CA CA002474785A patent/CA2474785A1/fr not_active Abandoned
- 2003-02-17 EP EP03720618A patent/EP1476421A2/fr not_active Withdrawn
- 2003-02-17 UA UA20040907682A patent/UA77763C2/uk unknown
- 2003-02-21 AR ARP030100563A patent/AR038443A1/es not_active Application Discontinuation
-
2004
- 2004-07-28 ZA ZA200406027A patent/ZA200406027B/en unknown
- 2004-09-20 NO NO20043910A patent/NO20043910L/no not_active Application Discontinuation
- 2004-09-20 MA MA27865A patent/MA27110A1/fr unknown
-
2005
- 2005-12-22 HK HK05111846A patent/HK1079764A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MA27110A1 (fr) | 2004-12-20 |
CA2474785A1 (fr) | 2003-08-28 |
FR2836143B1 (fr) | 2004-04-16 |
EP1476421A2 (fr) | 2004-11-17 |
GEP20074100B (en) | 2007-05-10 |
KR20040085219A (ko) | 2004-10-07 |
EA200401011A1 (ru) | 2004-12-30 |
JP2005517734A (ja) | 2005-06-16 |
UA77763C2 (en) | 2007-01-15 |
MXPA04007988A (es) | 2004-11-26 |
US7265220B2 (en) | 2007-09-04 |
AR038443A1 (es) | 2005-01-12 |
EA006389B1 (ru) | 2005-12-29 |
NZ534359A (en) | 2005-12-23 |
CN1257889C (zh) | 2006-05-31 |
BR0307776A (pt) | 2004-12-07 |
ZA200406027B (en) | 2006-06-28 |
NO20043910L (no) | 2004-09-20 |
WO2003070690A2 (fr) | 2003-08-28 |
AU2003224198A1 (en) | 2003-09-09 |
CN1633412A (zh) | 2005-06-29 |
JP4106337B2 (ja) | 2008-06-25 |
US20050085517A1 (en) | 2005-04-21 |
FR2836143A1 (fr) | 2003-08-22 |
PL370817A1 (en) | 2005-05-30 |
KR100668194B1 (ko) | 2007-01-11 |
WO2003070690A3 (fr) | 2004-04-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20100217 |