HK1078585A1 - Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases - Google Patents

Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases

Info

Publication number
HK1078585A1
HK1078585A1 HK05110413A HK05110413A HK1078585A1 HK 1078585 A1 HK1078585 A1 HK 1078585A1 HK 05110413 A HK05110413 A HK 05110413A HK 05110413 A HK05110413 A HK 05110413A HK 1078585 A1 HK1078585 A1 HK 1078585A1
Authority
HK
Hong Kong
Prior art keywords
benign
treatment
water
platinum compounds
porphyrin platinum
Prior art date
Application number
HK05110413A
Other languages
English (en)
Inventor
Karl-Legien Bart
Gunther Bernhardt
Henri Brunner
Christian Lottner
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of HK1078585A1 publication Critical patent/HK1078585A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyethers (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK05110413A 2002-02-01 2005-11-18 Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases HK1078585A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35358502P 2002-02-01 2002-02-01
PCT/EP2003/000874 WO2003064424A2 (en) 2002-02-01 2003-01-29 Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases

Publications (1)

Publication Number Publication Date
HK1078585A1 true HK1078585A1 (en) 2006-03-17

Family

ID=27663224

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05110413A HK1078585A1 (en) 2002-02-01 2005-11-18 Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases

Country Status (19)

Country Link
US (1) US7087214B2 (es)
EP (1) EP1470139A2 (es)
JP (1) JP2005522429A (es)
KR (1) KR20040083098A (es)
CN (1) CN1303090C (es)
AR (1) AR038479A1 (es)
BR (1) BR0307400A (es)
CA (1) CA2418410A1 (es)
HK (1) HK1078585A1 (es)
HR (1) HRP20040788A2 (es)
MX (1) MXPA04007443A (es)
NO (1) NO20043650L (es)
NZ (1) NZ534541A (es)
PL (1) PL373346A1 (es)
RU (1) RU2004126637A (es)
TW (1) TWI233929B (es)
UA (1) UA78007C2 (es)
WO (1) WO2003064424A2 (es)
ZA (1) ZA200405925B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
EP1950217A1 (en) * 2007-01-26 2008-07-30 Université de Neuchâtel Organometallic compounds for the treatment of cancer
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
JP5823413B2 (ja) * 2010-01-22 2015-11-25 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ 新規なポルフィリン誘導体の製造方法、ならびにｐｄｔ剤および蛍光プローブとしてのそれらの使用
CN102408452B (zh) * 2011-12-13 2014-09-03 中山大学 四吡啶基卟啉桥联十字形四核铂配合物及其制备方法和抗肿瘤活性
RU2682674C2 (ru) 2013-03-15 2019-03-20 Шерри Энн МАКФАРЛЭНД Координационные комплексы на основе металлов в качестве фотодинамических соединений и их применение
WO2019217606A1 (en) * 2018-05-09 2019-11-14 Virginia Commonwealth University Near-ir activatable fluorescent small molecules with dual modes of cytotoxicity
CN109251206B (zh) * 2018-09-21 2022-02-08 上海大学 水溶性铂-卟啉配合物及其制备方法
CN110028513B (zh) * 2019-04-30 2020-12-11 北京太阳升高科医药研究股份有限公司 卟啉衍生物及声敏剂
CN110590852B (zh) * 2019-08-29 2022-12-09 合肥学院 一种具有抗肿瘤活性的铂配合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0615545B2 (ja) * 1984-10-01 1994-03-02 東洋薄荷工業株式会社 金属フェオホーバイド誘導体および金属ポルフィリン誘導体
ZA86704B (en) 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
EP0220686B1 (en) * 1985-10-23 1992-12-30 Nihon Medi-Physics Co., Ltd. Porphyrin derivatives, and their production and use
DE19824653A1 (de) 1998-02-25 1999-08-26 Schering Ag Nekrose-affine Verbindungen und ihre Verwendung zur Herstellung von Präparaten zur Pharmakotherapie

Also Published As

Publication number Publication date
CN1639178A (zh) 2005-07-13
NO20043650L (no) 2004-10-29
TWI233929B (en) 2005-06-11
US7087214B2 (en) 2006-08-08
PL373346A1 (en) 2005-08-22
WO2003064424A2 (en) 2003-08-07
MXPA04007443A (es) 2004-10-11
JP2005522429A (ja) 2005-07-28
BR0307400A (pt) 2004-12-21
NZ534541A (en) 2005-10-28
KR20040083098A (ko) 2004-09-30
US20040023942A1 (en) 2004-02-05
CA2418410A1 (en) 2003-08-01
EP1470139A2 (en) 2004-10-27
RU2004126637A (ru) 2006-02-10
TW200305571A (en) 2003-11-01
UA78007C2 (en) 2007-02-15
ZA200405925B (en) 2004-09-07
WO2003064424A3 (en) 2004-01-15
CN1303090C (zh) 2007-03-07
AR038479A1 (es) 2005-01-19
HRP20040788A2 (en) 2004-12-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110129