HK1073064A1 - Means for improving immune response - Google Patents

Means for improving immune response

Info

Publication number
HK1073064A1
HK1073064A1 HK05105626A HK05105626A HK1073064A1 HK 1073064 A1 HK1073064 A1 HK 1073064A1 HK 05105626 A HK05105626 A HK 05105626A HK 05105626 A HK05105626 A HK 05105626A HK 1073064 A1 HK1073064 A1 HK 1073064A1
Authority
HK
Hong Kong
Prior art keywords
immune response
expression constructs
elicit
intradermal injection
cell mediated
Prior art date
Application number
HK05105626A
Other languages
English (en)
Inventor
Sonia Moreno Lopez
Timon Jimenez Marcos
Original Assignee
Mologen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mologen Ag filed Critical Mologen Ag
Publication of HK1073064A1 publication Critical patent/HK1073064A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Amplifiers (AREA)
HK05105626A 2001-10-02 2005-07-05 Means for improving immune response HK1073064A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10148697 2001-10-02
DE10156678 2001-11-12
PCT/DE2002/003798 WO2003031469A2 (de) 2001-10-02 2002-10-02 Mittel zur verbesserung der immunantwort

Publications (1)

Publication Number Publication Date
HK1073064A1 true HK1073064A1 (en) 2005-09-23

Family

ID=26010281

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105626A HK1073064A1 (en) 2001-10-02 2005-07-05 Means for improving immune response

Country Status (11)

Country Link
US (1) US20040235771A1 (zh)
EP (1) EP1432439B1 (zh)
CN (1) CN1310676C (zh)
AT (1) ATE311899T1 (zh)
AU (1) AU2002349277A1 (zh)
CY (1) CY1105447T1 (zh)
DE (1) DE50205223D1 (zh)
DK (1) DK1432439T3 (zh)
ES (1) ES2254758T3 (zh)
HK (1) HK1073064A1 (zh)
WO (1) WO2003031469A2 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150050317A1 (en) * 2013-08-19 2015-02-19 Mologen Ag Means for Eliciting an Immune Response and a Method Therefor
WO2004106365A2 (en) * 2003-05-28 2004-12-09 Aventis Pasteur, Inc. Modulatory peptide motifs for inducing th1 or th2 immune response
WO2005039633A1 (de) * 2003-10-24 2005-05-06 Mologen Ag Mittel zur behandlung von infektionen mit leishmanien
PT1699480E (pt) 2003-12-30 2011-08-30 Mologen Ag AGENTE TERAPjUTICO ANTI-TUMORAL ALOGÉNICO
WO2005080567A1 (de) * 2004-02-20 2005-09-01 Mologen Ag Substituiertes, nicht-kodierendes nukleinsäuremolekül zur therapeutischen und prophylaktischen immunstimulation in menschen und höheren tieren
ES2247942B1 (es) * 2004-08-27 2006-10-01 Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria (Inia) Construccion genica, vector y vacuna adn para la vacunacion de animales acuaticos.
WO2007080203A1 (es) * 2006-01-11 2007-07-19 Instituto Nacional De Investigación Y Tecnología Agraria Y Alimentaria (Inia) Construcción genica, vector y vacuna de adn para la vacunación de animales acuáticos
CN103703375B (zh) * 2011-06-29 2018-04-10 塞尔雷斯蒂斯有限公司 具有增强灵敏度的细胞介导免疫应答测定
CN103665169B (zh) * 2013-11-21 2016-01-06 上海海洋大学 三功能肽修饰的基因载体及其制备方法与应用
LU92821B1 (en) 2015-09-09 2017-03-20 Mologen Ag Combination comprising immunostimulatory oligonucleotides
GB2542425A (en) 2015-09-21 2017-03-22 Mologen Ag Means for the treatment of HIV
KR20200144540A (ko) * 2018-03-06 2020-12-29 페프박스, 인코포레이티드 핵산 분자 및 그 사용 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648625A1 (de) * 1996-11-13 1998-05-14 Soft Gene Gmbh Mikroprojektil für das Einbringen von Substanzen in Zellen durch ballistischen Transfer

Also Published As

Publication number Publication date
WO2003031469A2 (de) 2003-04-17
ES2254758T3 (es) 2006-06-16
EP1432439B1 (de) 2005-12-07
ATE311899T1 (de) 2005-12-15
US20040235771A1 (en) 2004-11-25
AU2002349277A1 (en) 2003-04-22
DK1432439T3 (da) 2006-04-03
CY1105447T1 (el) 2010-04-28
CN1310676C (zh) 2007-04-18
WO2003031469A3 (de) 2003-10-30
DE50205223D1 (de) 2006-01-12
CN1564694A (zh) 2005-01-12
EP1432439A2 (de) 2004-06-30

Similar Documents

Publication Publication Date Title
HK1073064A1 (en) Means for improving immune response
EP1173460A4 (en) PREPARATIONS AND METHODS FOR USE IN RECOMBINATORY CLONING OF NUCLEIC ACIDS
WO2002012281A3 (en) Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen
ES2132395T3 (es) Especificidad lisosomica de inmunogenos.
DE60142922D1 (de) Für antigene polypeptide des hiv type c kodierende nukleinsäuren, entsprechende polypeptide und verwendungen davon
WO1997048370A3 (en) Vaccines comprising synthetic genes
NO940736L (no) DNA sekvenser som koder for gelonin polypeptid
HUT71847A (en) Dna molecules encoding aminopeptidase enzymes, vectors and transgenic cells containing dna molecules, immunogenic polypeptides encoding by dna molecules, vaccines against helminth infections containing these peptides and process for the preparation ...
EP0796104A4 (en) THE INTRODUCTION OF NUCLEIC ACID MOLECULES INTO MUCUTINE TISSUE
AU7093601A (en) Nucleic acid molecules encoding plant cell cycle proteins and uses therefor
PL1962889T3 (pl) Immunogenny polipeptyd złożony z optymalizowanych kryptycznych peptydów wyprowadzonych z antygenu nowotworu oraz jego zastosowania
DE60143029D1 (de) M necrophorum und dessen präparation
GB9727512D0 (en) Fuzzy genes and their application in molecular adjuvants
CA2370278A1 (en) Chimeric lyssavirus nucleic acids and polypeptides
WO2000064488A3 (en) Somatic transgene immunization and related methods
AU2001251410A1 (en) 12303, a novel human twik molecule and uses thereof
Arya Suppositories as carriers of epitopes to enteric and genital mucosal immune system
HU9602084D0 (en) Expression of heterologous proteins in attenuated bacteria using the htra-promoters
Flores et al. Molecular cloning of rotaviral genes: Implications for immunoprophylaxis.
Aurisicchio et al. Immunization with genetic vectors expressing rhesus CEA efficiently breaks immune tolerance in mice and rhesus monkeys
WO2002033081A3 (en) Veterinary immunisation vectors comprising nucleic acid sequences encoding variants of non-human c3d polypeptides
WO2002026983A3 (en) 56115, a novel human twik potassium channel and uses therefor
WO2001081414A3 (en) Integrin alpha subunit and uses thereof

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181002