HK1072609A1 - New etonogestrel esters - Google Patents

New etonogestrel esters

Info

Publication number
HK1072609A1
HK1072609A1 HK05105350A HK05105350A HK1072609A1 HK 1072609 A1 HK1072609 A1 HK 1072609A1 HK 05105350 A HK05105350 A HK 05105350A HK 05105350 A HK05105350 A HK 05105350A HK 1072609 A1 HK1072609 A1 HK 1072609A1
Authority
HK
Hong Kong
Prior art keywords
new
etonogestrel esters
esters
new etonogestrel
etonogestrel
Prior art date
Application number
HK05105350A
Other languages
English (en)
Inventor
Nrik De Nijs
Hendrikus Adrianus Anton Voort
Dirk Leysen
Arij Jan Grootenhuis
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of HK1072609A1 publication Critical patent/HK1072609A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK05105350A 2002-05-30 2005-06-28 New etonogestrel esters HK1072609A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077119 2002-05-30
PCT/EP2003/050187 WO2003102012A2 (en) 2002-05-30 2003-05-22 New etonogestrel esters

Publications (1)

Publication Number Publication Date
HK1072609A1 true HK1072609A1 (en) 2005-09-02

Family

ID=29595014

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105350A HK1072609A1 (en) 2002-05-30 2005-06-28 New etonogestrel esters

Country Status (31)

Country Link
US (1) US7323454B2 (da)
EP (1) EP1513861B1 (da)
JP (1) JP4716726B2 (da)
KR (1) KR20050009723A (da)
CN (2) CN101100480A (da)
AR (1) AR040130A1 (da)
AT (1) ATE349458T1 (da)
AU (1) AU2003238081B2 (da)
BR (1) BR0311254A (da)
CA (1) CA2487722C (da)
CO (1) CO5631449A2 (da)
DE (1) DE60310714T2 (da)
DK (1) DK1513861T3 (da)
ES (1) ES2277085T3 (da)
HK (1) HK1072609A1 (da)
HR (1) HRP20041101A2 (da)
IL (1) IL165087A0 (da)
IS (1) IS2421B (da)
MX (1) MXPA04011797A (da)
NO (1) NO20044898L (da)
NZ (1) NZ536619A (da)
PE (1) PE20040068A1 (da)
PL (1) PL373855A1 (da)
PT (1) PT1513861E (da)
RS (1) RS97604A (da)
RU (1) RU2325910C2 (da)
SI (1) SI1513861T1 (da)
TW (1) TW200403065A (da)
UA (1) UA80126C2 (da)
WO (1) WO2003102012A2 (da)
ZA (1) ZA200410410B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200400041A (en) * 2002-05-30 2004-01-01 Akzo Nobel Nv Use of new etonogestrel esters
EP1909973B1 (en) 2005-07-15 2018-08-22 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
PL2019657T3 (pl) 2006-04-26 2015-10-30 Micell Technologies Inc Powłoki zawierające wiele leków
WO2008086369A1 (en) 2007-01-08 2008-07-17 Micell Technologies, Inc. Stents having biodegradable layers
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
US9433516B2 (en) 2007-04-17 2016-09-06 Micell Technologies, Inc. Stents having controlled elution
EA020655B1 (ru) 2008-04-17 2014-12-30 Миселл Текнолоджиз, Инк. Стенты, имеющие биорассасывающиеся слои
JP2011528275A (ja) 2008-07-17 2011-11-17 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
CA2756386C (en) 2009-03-23 2019-01-15 Micell Technologies, Inc. Drug delivery medical device
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
EP2453834A4 (en) 2009-07-16 2014-04-16 Micell Technologies Inc MEDICAL DEVICE DISPENSING MEDICINE
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
EP2560576B1 (en) 2010-04-22 2018-07-18 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
US20130172853A1 (en) 2010-07-16 2013-07-04 Micell Technologies, Inc. Drug delivery medical device
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
US11039943B2 (en) 2013-03-12 2021-06-22 Micell Technologies, Inc. Bioabsorbable biomedical implants
AU2014265460B2 (en) 2013-05-15 2018-10-18 Micell Technologies, Inc. Bioabsorbable biomedical implants
RU2595818C1 (ru) * 2015-05-25 2016-08-27 Федеральное государственное бюджетное научное учреждение "Научный центр проблем здоровья семьи и репродукции человека" Способ комплексного лечения дисфункции яичников при применении гормонального контрацептива имплантата "импланона"
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB845442A (en) 1956-03-22 1960-08-24 Schering Ag Manufacture of steroid compounds
DE1013284B (de) 1956-03-22 1957-08-08 Schering Ag Verfahren zur Einfuehrung der Reste wenig reaktionsfaehiger Carbonsaeuren, insbesondere des ª‰-Cyclopentyl-propionylrestes, in die 17ª‡-staendige Oxygruppe solcher Steroide, die am Kohlenstoffatom 17 neben der Oxygruppe eine Acetylgruppe tragen
GB8313921D0 (en) * 1983-05-19 1983-06-22 World Health Org Contraceptive compositions
DE4227989A1 (de) 1992-08-21 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel
DE4240806A1 (de) 1992-12-01 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 14alpha,17alpha-Ethanoestra-1,3,5(10)-trien-3,17beta-diol
JPH07101884A (ja) 1993-10-01 1995-04-18 Sanei Gen F F I Inc 水溶性ヘミセルロースを含有する製剤
CZ187796A3 (en) 1993-12-27 1997-01-15 Akzo Nobel Nv Pharmaceutical preparation
AU6614096A (en) * 1995-07-17 1997-02-18 Schering Aktiengesellschaft Agent, for transdermal application, containing esters of 3-ketodesogestrel
DE19613698A1 (de) 1995-07-17 1997-01-23 Schering Ag Mittel zur transdermalen Applikation enthaltend Ester des 13-Ethyl-17ß-hydroxy-11-methylen-18,19-dinor-17alpha-pregn-4-en-20-yn-3-ons
AU4513099A (en) 1998-06-19 2000-01-10 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
HUP0102274A3 (en) 1998-06-19 2002-08-28 Akzo Nobel Nv Testosterone derivative and pharmaceutical compositions containing the same
US6180682B1 (en) 1999-01-26 2001-01-30 Virgil A. Place Buccal drug delivery system for use in male contraception
TW200400041A (en) * 2002-05-30 2004-01-01 Akzo Nobel Nv Use of new etonogestrel esters

Also Published As

Publication number Publication date
ZA200410410B (en) 2006-02-22
DE60310714D1 (de) 2007-02-08
RS97604A (en) 2006-10-27
AU2003238081A1 (en) 2003-12-19
CN101100480A (zh) 2008-01-09
HRP20041101A2 (en) 2004-12-31
SI1513861T1 (sl) 2007-06-30
JP2005532350A (ja) 2005-10-27
JP4716726B2 (ja) 2011-07-06
ES2277085T3 (es) 2007-07-01
AU2003238081B2 (en) 2008-09-18
DK1513861T3 (da) 2007-04-10
PE20040068A1 (es) 2004-02-18
EP1513861B1 (en) 2006-12-27
CA2487722A1 (en) 2003-12-11
PL373855A1 (en) 2005-09-19
ATE349458T1 (de) 2007-01-15
BR0311254A (pt) 2005-03-15
CN1314701C (zh) 2007-05-09
UA80126C2 (en) 2007-08-27
US20050222113A1 (en) 2005-10-06
CN1692122A (zh) 2005-11-02
WO2003102012A9 (en) 2005-01-13
IS7528A (is) 2004-11-15
TW200403065A (en) 2004-03-01
RU2325910C2 (ru) 2008-06-10
AR040130A1 (es) 2005-03-16
WO2003102012A3 (en) 2004-04-22
CO5631449A2 (es) 2006-04-28
MXPA04011797A (es) 2005-03-31
KR20050009723A (ko) 2005-01-25
NO20044898L (no) 2005-02-25
NZ536619A (en) 2007-09-28
US7323454B2 (en) 2008-01-29
PT1513861E (pt) 2007-03-30
EP1513861A2 (en) 2005-03-16
CA2487722C (en) 2011-07-19
DE60310714T2 (de) 2007-10-11
RU2004138807A (ru) 2005-05-27
IL165087A0 (en) 2005-12-18
IS2421B (is) 2008-10-15
WO2003102012A2 (en) 2003-12-11

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160522