HK1062579A1 - A fusion protein for treatment of hepatitis b virus and its use thereof - Google Patents
A fusion protein for treatment of hepatitis b virus and its use thereofInfo
- Publication number
- HK1062579A1 HK1062579A1 HK04105433A HK04105433A HK1062579A1 HK 1062579 A1 HK1062579 A1 HK 1062579A1 HK 04105433 A HK04105433 A HK 04105433A HK 04105433 A HK04105433 A HK 04105433A HK 1062579 A1 HK1062579 A1 HK 1062579A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hepatitis
- virus
- treatment
- fusion protein
- fusion
- Prior art date
Links
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26673301P | 2001-02-05 | 2001-02-05 | |
PCT/US2002/003460 WO2002062959A2 (en) | 2001-02-05 | 2002-02-05 | Hepatitis b virus treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1062579A1 true HK1062579A1 (en) | 2004-11-12 |
Family
ID=23015782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04105433A HK1062579A1 (en) | 2001-02-05 | 2004-07-22 | A fusion protein for treatment of hepatitis b virus and its use thereof |
Country Status (16)
Country | Link |
---|---|
US (2) | US6921534B2 (es) |
EP (1) | EP1357940A4 (es) |
JP (1) | JP2005505238A (es) |
KR (1) | KR20030074787A (es) |
CN (1) | CN1264572C (es) |
AU (1) | AU2002247084B2 (es) |
BR (1) | BR0206995A (es) |
CA (1) | CA2437503A1 (es) |
HK (1) | HK1062579A1 (es) |
IL (2) | IL157251A0 (es) |
MX (1) | MXPA03006971A (es) |
NZ (1) | NZ527664A (es) |
PL (1) | PL373675A1 (es) |
RU (1) | RU2295536C2 (es) |
WO (1) | WO2002062959A2 (es) |
ZA (1) | ZA200306040B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1107681C (zh) * | 2000-08-11 | 2003-05-07 | 中国科学院微生物研究所 | 乙肝病毒抗原多肽与热休克蛋白的复合物及其应用 |
CN100381463C (zh) * | 2002-09-18 | 2008-04-16 | 中国人民解放军免疫学研究所 | 用于生产治疗用乙型肝炎疫苗或药物的免疫原及其制备方法和用途 |
GB0303507D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
CN1727362B (zh) * | 2004-07-30 | 2010-12-01 | 中国人民解放军第二军医大学 | 癌胚抗原阳性肿瘤治疗性疫苗的制备及应用 |
JP4736413B2 (ja) * | 2004-12-14 | 2011-07-27 | 富士ゼロックス株式会社 | 生体分子保持物及び生体分子の保存方法 |
US8691772B2 (en) * | 2005-01-04 | 2014-04-08 | Yeda Research And Development Co. Ltd. | HSP60, HSP60 peptides and T cell vaccines for immunomodulation |
WO2006097914A2 (en) * | 2005-03-14 | 2006-09-21 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Compositions of hsp60 peptides and viral antigens for vaccination and diagnosis |
US7622121B2 (en) * | 2005-09-21 | 2009-11-24 | New York University | Heat shock proteins from Mycobacterium leprae and uses thereof |
CN101307310B (zh) * | 2007-05-15 | 2012-08-08 | 康泰生医科技股份有限公司 | 具有提高产率及免疫原性的重组蛋白质表达系统 |
US8470372B2 (en) * | 2007-06-18 | 2013-06-25 | Shanghai Zerun-Ankegens Biopharmaceutical Company, Ltd. | Material with immunogenicity |
US8088392B2 (en) * | 2007-06-18 | 2012-01-03 | Yunxu Cao | Capsid proteins and uses therefore |
KR101281098B1 (ko) * | 2011-06-30 | 2013-07-02 | 주식회사 녹십자 | B형 간염 바이러스 표면 항원상의 에피토프 및 이의 용도 |
TWI623618B (zh) * | 2011-07-12 | 2018-05-11 | 傳斯堅公司 | Hbv聚合酶突變體 |
EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
BR112020011976A2 (pt) * | 2017-12-19 | 2020-11-24 | Janssen Sciences Ireland Unlimited Company | composição e kit imunogênicos contra o vírus da hepatite b, usos dos mesmos, e molécula de ácido nucleico de ocorrência não natural |
AU2020297008A1 (en) * | 2019-06-18 | 2022-02-17 | Janssen Sciences Ireland Unlimited Company | Combination of hepatitis B virus (HBV) vaccines and HBV-targeting RNAi |
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CN1107681C (zh) * | 2000-08-11 | 2003-05-07 | 中国科学院微生物研究所 | 乙肝病毒抗原多肽与热休克蛋白的复合物及其应用 |
-
2002
- 2002-02-05 KR KR10-2003-7010313A patent/KR20030074787A/ko not_active Application Discontinuation
- 2002-02-05 CA CA002437503A patent/CA2437503A1/en not_active Abandoned
- 2002-02-05 JP JP2002563296A patent/JP2005505238A/ja active Pending
- 2002-02-05 EP EP02714842A patent/EP1357940A4/en not_active Ceased
- 2002-02-05 MX MXPA03006971A patent/MXPA03006971A/es active IP Right Grant
- 2002-02-05 CN CNB028045769A patent/CN1264572C/zh not_active Expired - Fee Related
- 2002-02-05 RU RU2003127021/13A patent/RU2295536C2/ru not_active IP Right Cessation
- 2002-02-05 AU AU2002247084A patent/AU2002247084B2/en not_active Ceased
- 2002-02-05 IL IL15725102A patent/IL157251A0/xx unknown
- 2002-02-05 NZ NZ527664A patent/NZ527664A/en unknown
- 2002-02-05 WO PCT/US2002/003460 patent/WO2002062959A2/en active Application Filing
- 2002-02-05 US US10/068,059 patent/US6921534B2/en not_active Expired - Fee Related
- 2002-02-05 BR BR0206995-4A patent/BR0206995A/pt not_active IP Right Cessation
- 2002-02-05 PL PL02373675A patent/PL373675A1/xx unknown
-
2003
- 2003-08-05 ZA ZA200306040A patent/ZA200306040B/xx unknown
- 2003-08-05 IL IL157251A patent/IL157251A/en not_active IP Right Cessation
-
2004
- 2004-07-22 HK HK04105433A patent/HK1062579A1/xx not_active IP Right Cessation
- 2004-09-14 US US10/941,049 patent/US20050152917A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR0206995A (pt) | 2005-08-16 |
US20050152917A1 (en) | 2005-07-14 |
CN1264572C (zh) | 2006-07-19 |
EP1357940A2 (en) | 2003-11-05 |
IL157251A (en) | 2009-05-04 |
MXPA03006971A (es) | 2004-05-05 |
US20020155434A1 (en) | 2002-10-24 |
AU2002247084B2 (en) | 2007-01-04 |
RU2003127021A (ru) | 2005-01-20 |
WO2002062959A3 (en) | 2003-03-06 |
KR20030074787A (ko) | 2003-09-19 |
US6921534B2 (en) | 2005-07-26 |
IL157251A0 (en) | 2004-02-19 |
WO2002062959A2 (en) | 2002-08-15 |
RU2295536C2 (ru) | 2007-03-20 |
ZA200306040B (en) | 2004-11-17 |
PL373675A1 (en) | 2005-09-05 |
JP2005505238A (ja) | 2005-02-24 |
CN1491116A (zh) | 2004-04-21 |
NZ527664A (en) | 2006-12-22 |
EP1357940A4 (en) | 2004-03-17 |
CA2437503A1 (en) | 2002-08-15 |
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