HK1062174A1 - Benzimidazoles that are useful in treating sexual dysfunction - Google Patents

Benzimidazoles that are useful in treating sexual dysfunction

Info

Publication number
HK1062174A1
HK1062174A1 HK04104714A HK04104714A HK1062174A1 HK 1062174 A1 HK1062174 A1 HK 1062174A1 HK 04104714 A HK04104714 A HK 04104714A HK 04104714 A HK04104714 A HK 04104714A HK 1062174 A1 HK1062174 A1 HK 1062174A1
Authority
HK
Hong Kong
Prior art keywords
sexual dysfunction
benzimidazoles
useful
treating sexual
formula
Prior art date
Application number
HK04104714A
Other languages
English (en)
Inventor
Marlon D Cowart
Pramila A Bhatia
Jerome F Daanen
Andrew O Stewart
Teodozyj Kolasa
Jeffrey J Rhde
Meena V Patel
Jorge D Brioni
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/874,484 external-priority patent/US20030008878A1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of HK1062174A1 publication Critical patent/HK1062174A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Discharging, Photosensitive Material Shape In Electrophotography (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK04104714A 2001-03-09 2004-06-30 Benzimidazoles that are useful in treating sexual dysfunction HK1062174A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80353701A 2001-03-09 2001-03-09
US09/874,484 US20030008878A1 (en) 2001-03-09 2001-06-05 Benzimidazoles that are useful in treating sexual dysfunction
US10/017,939 US20020169166A1 (en) 2001-03-09 2001-12-14 Benzimidazoles that are useful in treating sexual dysfunction
PCT/US2002/007791 WO2002088093A1 (en) 2001-03-09 2002-03-06 Benzimidazoles that are useful in treating sexual dysfunction

Publications (1)

Publication Number Publication Date
HK1062174A1 true HK1062174A1 (en) 2004-10-21

Family

ID=27360930

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04104714A HK1062174A1 (en) 2001-03-09 2004-06-30 Benzimidazoles that are useful in treating sexual dysfunction

Country Status (23)

Country Link
US (1) US20020169166A1 (da)
EP (1) EP1373220B1 (da)
JP (1) JP2005507370A (da)
CN (1) CN100430383C (da)
AT (1) ATE363474T1 (da)
AU (1) AU2002303128B2 (da)
BG (1) BG108230A (da)
BR (1) BR0205812A (da)
CA (1) CA2439943A1 (da)
CZ (1) CZ20032659A3 (da)
DE (1) DE60220385T2 (da)
DK (1) DK1373220T3 (da)
ES (1) ES2287278T3 (da)
HK (1) HK1062174A1 (da)
HU (1) HUP0303413A3 (da)
IL (1) IL157457A0 (da)
MX (1) MXPA03008151A (da)
NO (1) NO326686B1 (da)
NZ (1) NZ527713A (da)
PL (1) PL371272A1 (da)
SK (1) SK12612003A3 (da)
UY (1) UY27203A1 (da)
WO (1) WO2002088093A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022728B2 (en) 2001-03-09 2006-04-04 Abbott Laboratories Benzimidazoles that are useful in treating male sexual dysfunction
US6960589B2 (en) * 2001-03-09 2005-11-01 Abbott Laboratories Benzimidazoles that are useful in treating sexual dysfunction
US20040127504A1 (en) * 2002-09-06 2004-07-01 Cowart Marlon D. Benzimidazoles that are useful in treating sexual dysfunction
ES2568769T3 (es) 2003-07-30 2016-05-04 Xenon Pharmaceuticals Inc. Derivados de piperazina y su uso como agentes terapéuticos
AU2004261267B9 (en) * 2003-07-30 2009-04-09 Xenon Pharmaceuticals Inc. Pyridyl derivatives and their use as therapeutic agents
AR045496A1 (es) * 2003-08-29 2005-11-02 Schering Corp Analolgos de benzimidazolpiperidinas 2- substiyuidas como antagonistas de los receptores de la hormona que concentra melanina selectivos para el tratamiento de la obesidad y trastornos relacionados
WO2006034279A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
TW200626155A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
AU2005329423A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515478A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seu uso como mediadores de estearoil-coa-desaturase
TW200626154A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
CN101083982A (zh) 2004-09-20 2007-12-05 泽农医药公司 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物
CN101084207A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
BRPI0611187A2 (pt) 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
WO2008079945A2 (en) * 2006-12-20 2008-07-03 University Of South Florida Rock inhibitors and uses thereof
EP2149373A1 (en) * 2008-08-01 2010-02-03 Laboratorios Del. Dr. Esteve, S.A. 5HT7 receptor ligands and compositions comprising the same
EP2545905A1 (en) 2011-07-11 2013-01-16 Britannia Pharmaceuticals Limited A new therapeutical composition containing apomorphine as active ingredient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
FR2665161B1 (fr) * 1990-07-26 1992-11-27 Esteve Labor Dr Nouveaux derives de benzimidazole, leur preparation et leur application en tant que medicaments.
GB9306578D0 (en) * 1993-03-30 1993-05-26 Merck Sharp & Dohme Therapeutic agents
DK0882718T3 (da) * 1995-12-28 2005-12-12 Astellas Pharma Inc Benzimidazolderivater
GB9700878D0 (en) * 1997-01-17 1997-03-05 Scherer Ltd R P Dosage forms and method for ameliorating male erectile dysfunction
CA2251255A1 (en) * 1998-10-20 2000-04-20 Mcgill University The use of dopaminergic agents in the management of sexual dysfunction
ES2154605B1 (es) * 1999-09-14 2001-11-16 Univ Madrid Complutense Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3

Also Published As

Publication number Publication date
EP1373220B1 (en) 2007-05-30
NZ527713A (en) 2006-09-29
HUP0303413A2 (hu) 2004-01-28
WO2002088093A1 (en) 2002-11-07
PL371272A1 (en) 2005-06-13
ES2287278T3 (es) 2007-12-16
EP1373220A1 (en) 2004-01-02
UY27203A1 (es) 2002-10-31
AU2002303128B2 (en) 2007-11-29
DE60220385D1 (de) 2007-07-12
BR0205812A (pt) 2005-05-03
DE60220385T2 (de) 2008-04-03
HUP0303413A3 (en) 2007-08-28
NO20033959D0 (no) 2003-09-08
CN100430383C (zh) 2008-11-05
NO326686B1 (no) 2009-01-26
MXPA03008151A (es) 2004-03-16
NO20033959L (no) 2003-11-10
US20020169166A1 (en) 2002-11-14
DK1373220T3 (da) 2007-10-08
JP2005507370A (ja) 2005-03-17
BG108230A (bg) 2005-04-30
ATE363474T1 (de) 2007-06-15
SK12612003A3 (sk) 2004-04-06
CA2439943A1 (en) 2002-11-07
IL157457A0 (en) 2004-03-28
CZ20032659A3 (cs) 2004-01-14
CN1516693A (zh) 2004-07-28

Similar Documents

Publication Publication Date Title
WO2003099266A3 (en) Acetamides and benzamides that are useful in treating sexual dysfunction
IL157457A0 (en) Benzimidazoles that are useful in treating sexual dysfuction
HK1069169A1 (en) Substituted tetracyclic pyrroloquinolone derivatives useful as phosphodiesterase inhibitors
MXPA04002593A (es) Composiciones y metodos para el diagnostico y tratamiento de tumor.
MXPA03011985A (es) Composiciones y metodos para el diagnostico y tratamiento de tumores.
TW200505903A (en) CGRP receptor antagonists
MXPA02011425A (es) Derivados sustituidos de pirrolopiridinona utiles como inhibidores de fosfodiesterasa.
MXPA03001645A (es) Composiciones y metodos para el diagnostico y tratamiento de tumores.
TW200504034A (en) Therapeutic agents
RS20050070A (en) Use of 1kb kinase inhibitors for the treatment of pain
YU75603A (sh) Dihidropirimidinska jedinjenja koja su supstituisana na cijano grupi i njihova upotreba u lečenju oboljenja
BG108180A (en) Novel cyano-substituted dihydropyrimidine compounds and their use to treat diseases
SI1546182T1 (sl) Sestavki in postopki za diagnozo in zdravljenje tumorja
BR0305708A (pt) Derivados de benzimidazol para o tratamento de disfunção sexual
MXPA03001643A (es) Composiciones y metodos para el diagnostico y tratamiento de tumores.
MXPA03004547A (es) Agonistas receptores de d4 de dopamina selectivos para el tratamiento de disfuncion sexual.
MXPA05011699A (es) Inhibidores de la bomba de protones para el tratamiento de trastornos del abdomen inferior.
TW200503722A (en) Substituted 7-aza-quinazoline compounds
MY139385A (en) Benzimidazoles that are useful in treating sexual dysfunction
MY139582A (en) Benzimidazoles that are useful in treating sexual dysfunction
MXPA05008293A (es) Composiciones y metodos para el diagnostico y tratamiento de tumores.
MXPA03001644A (es) Composiciones y metodos para el diagnostico y tratamiento de tumor.
TW200510374A (en) Benzimidazoles that are useful in treating sexual dysfunction
BR0306625A (pt) acetamidas e benzamidas que são úteis no tratamento de disfunção sexual
MY155220A (en) Selective dopamine d4 receptor agonists for treating sexual dysfunction

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110306