HK1058358A1 - Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders. - Google Patents

Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders.

Info

Publication number
HK1058358A1
HK1058358A1 HK04101071A HK04101071A HK1058358A1 HK 1058358 A1 HK1058358 A1 HK 1058358A1 HK 04101071 A HK04101071 A HK 04101071A HK 04101071 A HK04101071 A HK 04101071A HK 1058358 A1 HK1058358 A1 HK 1058358A1
Authority
HK
Hong Kong
Prior art keywords
sulfonyl
treatment
neurological disorders
derivatives useful
pyrrolidine derivatives
Prior art date
Application number
HK04101071A
Other languages
English (en)
Inventor
Vincent Mutel
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1058358A1 publication Critical patent/HK1058358A1/xx

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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
HK04101071A 2000-06-30 2004-02-16 Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders. HK1058358A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00113894 2000-06-30
PCT/EP2001/007135 WO2002002554A1 (en) 2000-06-30 2001-06-22 Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders

Publications (1)

Publication Number Publication Date
HK1058358A1 true HK1058358A1 (en) 2004-05-14

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US (2) US6589978B2 (xx)
EP (1) EP1299383B1 (xx)
JP (1) JP3994051B2 (xx)
KR (1) KR100529423B1 (xx)
CN (1) CN1178936C (xx)
AR (1) AR029288A1 (xx)
AT (1) ATE286895T1 (xx)
AU (2) AU8187701A (xx)
BR (1) BR0112093A (xx)
CA (1) CA2413243A1 (xx)
CZ (1) CZ2003280A3 (xx)
DE (1) DE60108394T2 (xx)
DK (1) DK1299383T3 (xx)
EC (1) ECSP024403A (xx)
ES (1) ES2234869T3 (xx)
HK (1) HK1058358A1 (xx)
HR (1) HRP20021023B1 (xx)
HU (1) HUP0301167A3 (xx)
IL (2) IL153425A0 (xx)
JO (1) JO2384B1 (xx)
MA (1) MA26923A1 (xx)
MX (1) MXPA02012270A (xx)
MY (1) MY126903A (xx)
NO (1) NO324218B1 (xx)
NZ (1) NZ523025A (xx)
PE (1) PE20020103A1 (xx)
PL (1) PL360396A1 (xx)
PT (1) PT1299383E (xx)
RU (1) RU2272026C2 (xx)
SI (1) SI1299383T1 (xx)
TW (1) TWI265928B (xx)
UY (1) UY26812A1 (xx)
WO (1) WO2002002554A1 (xx)
YU (1) YU99702A (xx)
ZA (1) ZA200209966B (xx)

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HUP0301167A3 (en) 2009-12-28
JO2384B1 (en) 2007-06-17
ATE286895T1 (de) 2005-01-15
UY26812A1 (es) 2001-12-28
MXPA02012270A (es) 2003-04-25
CN1440405A (zh) 2003-09-03
PE20020103A1 (es) 2002-02-13
TWI265928B (en) 2006-11-11
ECSP024403A (es) 2003-02-06
JP3994051B2 (ja) 2007-10-17
JP2004502688A (ja) 2004-01-29
SI1299383T1 (en) 2005-06-30
HRP20021023A2 (en) 2004-08-31
HUP0301167A2 (hu) 2003-08-28
YU99702A (sh) 2006-05-25
PT1299383E (pt) 2005-05-31
US6589978B2 (en) 2003-07-08
DE60108394D1 (de) 2005-02-17
RU2272026C2 (ru) 2006-03-20
US6995182B2 (en) 2006-02-07
NZ523025A (en) 2004-04-30
ZA200209966B (en) 2004-03-09
EP1299383A1 (en) 2003-04-09
IL153425A (en) 2007-08-19
NO324218B1 (no) 2007-09-10
US20030212066A1 (en) 2003-11-13
KR100529423B1 (ko) 2005-11-17
DK1299383T3 (da) 2005-05-23
KR20030011378A (ko) 2003-02-07
AU8187701A (en) 2002-01-14
CN1178936C (zh) 2004-12-08
HRP20021023B1 (en) 2006-08-31
NO20026263L (no) 2002-12-27
MY126903A (en) 2006-10-31
BR0112093A (pt) 2003-05-13
DE60108394T2 (de) 2006-03-02
NO20026263D0 (no) 2002-12-27
AU2001281877B2 (en) 2006-08-31
CZ2003280A3 (cs) 2003-12-17
AR029288A1 (es) 2003-06-18
US20020019424A1 (en) 2002-02-14
EP1299383B1 (en) 2005-01-12
MA26923A1 (fr) 2004-12-20
WO2002002554A1 (en) 2002-01-10
CA2413243A1 (en) 2002-01-10
PL360396A1 (en) 2004-09-06
IL153425A0 (en) 2003-07-06
ES2234869T3 (es) 2005-07-01

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