HK1056558A1 - Substituted 3.4-dihydro-pyrimido Ä1,2-aÜpyrimidines and 3.4-dihydropyrazino Ä1,2-aÜpyrimidines. - Google Patents

Substituted 3.4-dihydro-pyrimido Ä1,2-aÜpyrimidines and 3.4-dihydropyrazino Ä1,2-aÜpyrimidines.

Info

Publication number
HK1056558A1
HK1056558A1 HK03108915A HK03108915A HK1056558A1 HK 1056558 A1 HK1056558 A1 HK 1056558A1 HK 03108915 A HK03108915 A HK 03108915A HK 03108915 A HK03108915 A HK 03108915A HK 1056558 A1 HK1056558 A1 HK 1056558A1
Authority
HK
Hong Kong
Prior art keywords
aüpyrimidines
dihydropyrazino
pyrimido
dihydro
substituted
Prior art date
Application number
HK03108915A
Other languages
English (en)
Inventor
Matthias Gerlach
Corinna Maul
Utz-Peter Jagusch
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of HK1056558A1 publication Critical patent/HK1056558A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK03108915A 2000-10-13 2003-12-09 Substituted 3.4-dihydro-pyrimido Ä1,2-aÜpyrimidines and 3.4-dihydropyrazino Ä1,2-aÜpyrimidines. HK1056558A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050661A DE10050661A1 (de) 2000-10-13 2000-10-13 Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine
PCT/EP2001/011702 WO2002030934A1 (de) 2000-10-13 2001-10-10 Substituierte 3,4-dihydro-pyrimido[1,2-a]pyrimidine und 3,4-dihydropyrazino[1,2-a]pyrimidine

Publications (1)

Publication Number Publication Date
HK1056558A1 true HK1056558A1 (en) 2004-02-20

Family

ID=7659596

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03108915A HK1056558A1 (en) 2000-10-13 2003-12-09 Substituted 3.4-dihydro-pyrimido Ä1,2-aÜpyrimidines and 3.4-dihydropyrazino Ä1,2-aÜpyrimidines.

Country Status (26)

Country Link
US (1) US7226924B2 (zh)
EP (1) EP1325010B1 (zh)
JP (1) JP2004511485A (zh)
KR (1) KR20030036923A (zh)
CN (1) CN1243753C (zh)
AR (1) AR035496A1 (zh)
AT (1) ATE294180T1 (zh)
AU (1) AU2002214007A1 (zh)
BR (1) BR0114735A (zh)
CA (1) CA2425685A1 (zh)
DE (2) DE10050661A1 (zh)
EC (1) ECSP034554A (zh)
ES (1) ES2239168T3 (zh)
HK (1) HK1056558A1 (zh)
HU (1) HUP0302606A3 (zh)
IL (1) IL155379A0 (zh)
MX (1) MXPA03003199A (zh)
NO (1) NO20031588D0 (zh)
NZ (1) NZ525651A (zh)
PE (1) PE20020477A1 (zh)
PL (1) PL361777A1 (zh)
PT (1) PT1325010E (zh)
RU (1) RU2003113965A (zh)
SK (1) SK4152003A3 (zh)
WO (1) WO2002030934A1 (zh)
ZA (1) ZA200303634B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2590294A1 (en) 2004-12-13 2006-06-22 Sunesis Pharmaceuticals, Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558618A (en) * 1968-04-01 1971-01-26 Dow Chemical Co Novel 4h-pyrazino(1,2-a)pyrimidine-4-ones
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
HU178910B (en) * 1977-08-19 1982-07-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
JP2668259B2 (ja) * 1988-02-18 1997-10-27 塩野義製薬株式会社 複素環化合物および抗潰瘍剤
FI94531C (fi) * 1990-03-13 1995-09-25 Ime Intermed Enterpris Sa Menetelmä farmaseuttisesti aktiivisen 1,3,4,6,7,8-heksahydro-2H-pyrimido-(1,2-a)-pyrimidiinijohdannaisen valmistamiseksi
IT1263804B (it) * 1993-01-22 1996-09-03 Luso Farmaco Inst Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
US5843951A (en) * 1995-09-28 1998-12-01 Otsuka Pharmaceutical Factory Inc. Analgesic composition of pyrazolo(1,5-A) pyrimidines

Also Published As

Publication number Publication date
NZ525651A (en) 2004-10-29
HUP0302606A3 (en) 2007-03-28
RU2003113965A (ru) 2004-12-10
AU2002214007A1 (en) 2002-04-22
DE50106048D1 (de) 2005-06-02
DE10050661A1 (de) 2002-04-18
NO20031588L (no) 2003-04-08
CN1243753C (zh) 2006-03-01
KR20030036923A (ko) 2003-05-09
BR0114735A (pt) 2003-10-14
HUP0302606A2 (hu) 2004-07-28
PT1325010E (pt) 2005-08-31
CN1469879A (zh) 2004-01-21
US7226924B2 (en) 2007-06-05
ZA200303634B (en) 2004-08-12
EP1325010A1 (de) 2003-07-09
ES2239168T3 (es) 2005-09-16
CA2425685A1 (en) 2003-04-11
AR035496A1 (es) 2004-06-02
ATE294180T1 (de) 2005-05-15
JP2004511485A (ja) 2004-04-15
SK4152003A3 (en) 2003-10-07
IL155379A0 (en) 2003-11-23
EP1325010B1 (de) 2005-04-27
NO20031588D0 (no) 2003-04-08
PE20020477A1 (es) 2002-06-29
MXPA03003199A (es) 2004-03-18
PL361777A1 (en) 2004-10-04
ECSP034554A (es) 2003-05-26
US20030220322A1 (en) 2003-11-27
WO2002030934A1 (de) 2002-04-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20101010