AU2002214007A1 - Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines - Google Patents

Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines

Info

Publication number
AU2002214007A1
AU2002214007A1 AU2002214007A AU1400702A AU2002214007A1 AU 2002214007 A1 AU2002214007 A1 AU 2002214007A1 AU 2002214007 A AU2002214007 A AU 2002214007A AU 1400702 A AU1400702 A AU 1400702A AU 2002214007 A1 AU2002214007 A1 AU 2002214007A1
Authority
AU
Australia
Prior art keywords
pyrimidines
dihydropyrazino
pyrimido
dihydro
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002214007A
Inventor
Matthias Gerlach
Utz-Peter Jagusch
Corinna Maul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2002214007A1 publication Critical patent/AU2002214007A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2002214007A 2000-10-13 2001-10-10 Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines Abandoned AU2002214007A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10050661A DE10050661A1 (en) 2000-10-13 2000-10-13 New substituted 3,4-dihydro-pyrimido(1,2-a)pyrimidine and 3,4-dihydro-pyrazino(1,2-a)pyrimidine derivatives useful for the treatment of pain, urinary incontinence, pruritis, tinnitus and diarrhea
DE10050661 2000-10-13
PCT/EP2001/011702 WO2002030934A1 (en) 2000-10-13 2001-10-10 Substituted 3.4-dihydro-pyrimido[1,2-a]pyrimidines and 3.4-dihydropyrazino[1,2-a]pyrimidines

Publications (1)

Publication Number Publication Date
AU2002214007A1 true AU2002214007A1 (en) 2002-04-22

Family

ID=7659596

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002214007A Abandoned AU2002214007A1 (en) 2000-10-13 2001-10-10 Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines

Country Status (26)

Country Link
US (1) US7226924B2 (en)
EP (1) EP1325010B1 (en)
JP (1) JP2004511485A (en)
KR (1) KR20030036923A (en)
CN (1) CN1243753C (en)
AR (1) AR035496A1 (en)
AT (1) ATE294180T1 (en)
AU (1) AU2002214007A1 (en)
BR (1) BR0114735A (en)
CA (1) CA2425685A1 (en)
DE (2) DE10050661A1 (en)
EC (1) ECSP034554A (en)
ES (1) ES2239168T3 (en)
HK (1) HK1056558A1 (en)
HU (1) HUP0302606A3 (en)
IL (1) IL155379A0 (en)
MX (1) MXPA03003199A (en)
NO (1) NO20031588D0 (en)
NZ (1) NZ525651A (en)
PE (1) PE20020477A1 (en)
PL (1) PL361777A1 (en)
PT (1) PT1325010E (en)
RU (1) RU2003113965A (en)
SK (1) SK4152003A3 (en)
WO (1) WO2002030934A1 (en)
ZA (1) ZA200303634B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1828186A1 (en) 2004-12-13 2007-09-05 Sunesis Pharmaceuticals, Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558618A (en) * 1968-04-01 1971-01-26 Dow Chemical Co Novel 4h-pyrazino(1,2-a)pyrimidine-4-ones
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
HU178910B (en) * 1977-08-19 1982-07-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
JP2668259B2 (en) * 1988-02-18 1997-10-27 塩野義製薬株式会社 Heterocyclic compounds and anti-ulcer agents
FI94531C (en) * 1990-03-13 1995-09-25 Ime Intermed Enterpris Sa Process for the preparation of a pharmaceutically active 1,3,4,6,7,8-hexahydro-2H-pyrimido- (1,2-a) -pyrimidine derivative
IT1263804B (en) * 1993-01-22 1996-09-03 Luso Farmaco Inst PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST
EP0795555A4 (en) * 1995-09-28 1998-01-07 Otsuka Pharma Co Ltd Analgesics

Also Published As

Publication number Publication date
JP2004511485A (en) 2004-04-15
AR035496A1 (en) 2004-06-02
DE50106048D1 (en) 2005-06-02
EP1325010B1 (en) 2005-04-27
RU2003113965A (en) 2004-12-10
DE10050661A1 (en) 2002-04-18
US20030220322A1 (en) 2003-11-27
EP1325010A1 (en) 2003-07-09
US7226924B2 (en) 2007-06-05
SK4152003A3 (en) 2003-10-07
HK1056558A1 (en) 2004-02-20
HUP0302606A3 (en) 2007-03-28
MXPA03003199A (en) 2004-03-18
NO20031588L (en) 2003-04-08
ATE294180T1 (en) 2005-05-15
ECSP034554A (en) 2003-05-26
WO2002030934A1 (en) 2002-04-18
IL155379A0 (en) 2003-11-23
NO20031588D0 (en) 2003-04-08
ES2239168T3 (en) 2005-09-16
CN1243753C (en) 2006-03-01
HUP0302606A2 (en) 2004-07-28
CA2425685A1 (en) 2003-04-11
KR20030036923A (en) 2003-05-09
ZA200303634B (en) 2004-08-12
PE20020477A1 (en) 2002-06-29
PL361777A1 (en) 2004-10-04
BR0114735A (en) 2003-10-14
CN1469879A (en) 2004-01-21
PT1325010E (en) 2005-08-31
NZ525651A (en) 2004-10-29

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application