PT1325010E - 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas - Google Patents
3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidasInfo
- Publication number
- PT1325010E PT1325010E PT01982417T PT01982417T PT1325010E PT 1325010 E PT1325010 E PT 1325010E PT 01982417 T PT01982417 T PT 01982417T PT 01982417 T PT01982417 T PT 01982417T PT 1325010 E PT1325010 E PT 1325010E
- Authority
- PT
- Portugal
- Prior art keywords
- pyrimidines
- dihydropyrimido
- dihydropyrazine
- replaced
- pyrimidines replaced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10050661A DE10050661A1 (de) | 2000-10-13 | 2000-10-13 | Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1325010E true PT1325010E (pt) | 2005-08-31 |
Family
ID=7659596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01982417T PT1325010E (pt) | 2000-10-13 | 2001-10-10 | 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas |
Country Status (26)
Country | Link |
---|---|
US (1) | US7226924B2 (pt) |
EP (1) | EP1325010B1 (pt) |
JP (1) | JP2004511485A (pt) |
KR (1) | KR20030036923A (pt) |
CN (1) | CN1243753C (pt) |
AR (1) | AR035496A1 (pt) |
AT (1) | ATE294180T1 (pt) |
AU (1) | AU2002214007A1 (pt) |
BR (1) | BR0114735A (pt) |
CA (1) | CA2425685A1 (pt) |
DE (2) | DE10050661A1 (pt) |
EC (1) | ECSP034554A (pt) |
ES (1) | ES2239168T3 (pt) |
HK (1) | HK1056558A1 (pt) |
HU (1) | HUP0302606A3 (pt) |
IL (1) | IL155379A0 (pt) |
MX (1) | MXPA03003199A (pt) |
NO (1) | NO20031588L (pt) |
NZ (1) | NZ525651A (pt) |
PE (1) | PE20020477A1 (pt) |
PL (1) | PL361777A1 (pt) |
PT (1) | PT1325010E (pt) |
RU (1) | RU2003113965A (pt) |
SK (1) | SK4152003A3 (pt) |
WO (1) | WO2002030934A1 (pt) |
ZA (1) | ZA200303634B (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005316668B2 (en) | 2004-12-13 | 2012-09-06 | Millennium Pharmaceuticals, Inc. | Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors |
US20070155738A1 (en) | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3558618A (en) * | 1968-04-01 | 1971-01-26 | Dow Chemical Co | Novel 4h-pyrazino(1,2-a)pyrimidine-4-ones |
GB1347493A (en) * | 1971-02-11 | 1974-02-27 | Aspro Nicholas Ltd | Benzazine derivatives |
HU178910B (en) * | 1977-08-19 | 1982-07-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines |
JP2668259B2 (ja) * | 1988-02-18 | 1997-10-27 | 塩野義製薬株式会社 | 複素環化合物および抗潰瘍剤 |
FI94531C (fi) * | 1990-03-13 | 1995-09-25 | Ime Intermed Enterpris Sa | Menetelmä farmaseuttisesti aktiivisen 1,3,4,6,7,8-heksahydro-2H-pyrimido-(1,2-a)-pyrimidiinijohdannaisen valmistamiseksi |
IT1263804B (it) * | 1993-01-22 | 1996-09-03 | Luso Farmaco Inst | Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista |
EP0795555A4 (en) * | 1995-09-28 | 1998-01-07 | Otsuka Pharma Co Ltd | ANALGETICS |
-
2000
- 2000-10-13 DE DE10050661A patent/DE10050661A1/de not_active Withdrawn
-
2001
- 2001-10-09 AR ARP010104730A patent/AR035496A1/es not_active Application Discontinuation
- 2001-10-10 BR BR0114735-8A patent/BR0114735A/pt not_active IP Right Cessation
- 2001-10-10 DE DE50106048T patent/DE50106048D1/de not_active Expired - Lifetime
- 2001-10-10 RU RU2003113965/04A patent/RU2003113965A/ru not_active Application Discontinuation
- 2001-10-10 AU AU2002214007A patent/AU2002214007A1/en not_active Abandoned
- 2001-10-10 IL IL15537901A patent/IL155379A0/xx unknown
- 2001-10-10 CA CA002425685A patent/CA2425685A1/en not_active Abandoned
- 2001-10-10 NZ NZ525651A patent/NZ525651A/en unknown
- 2001-10-10 AT AT01982417T patent/ATE294180T1/de active
- 2001-10-10 KR KR10-2003-7005149A patent/KR20030036923A/ko not_active Application Discontinuation
- 2001-10-10 WO PCT/EP2001/011702 patent/WO2002030934A1/de active IP Right Grant
- 2001-10-10 MX MXPA03003199A patent/MXPA03003199A/es active IP Right Grant
- 2001-10-10 CN CNB018171591A patent/CN1243753C/zh not_active Expired - Fee Related
- 2001-10-10 ES ES01982417T patent/ES2239168T3/es not_active Expired - Lifetime
- 2001-10-10 PL PL01361777A patent/PL361777A1/xx not_active Application Discontinuation
- 2001-10-10 EP EP01982417A patent/EP1325010B1/de not_active Expired - Lifetime
- 2001-10-10 JP JP2002534320A patent/JP2004511485A/ja not_active Withdrawn
- 2001-10-10 SK SK415-2003A patent/SK4152003A3/sk unknown
- 2001-10-10 HU HU0302606A patent/HUP0302606A3/hu unknown
- 2001-10-10 PT PT01982417T patent/PT1325010E/pt unknown
- 2001-10-12 PE PE2001001013A patent/PE20020477A1/es not_active Application Discontinuation
-
2003
- 2003-04-08 NO NO20031588A patent/NO20031588L/no unknown
- 2003-04-09 US US10/409,614 patent/US7226924B2/en not_active Expired - Fee Related
- 2003-04-11 EC EC2003004554A patent/ECSP034554A/es unknown
- 2003-05-12 ZA ZA200303634A patent/ZA200303634B/en unknown
- 2003-12-09 HK HK03108915A patent/HK1056558A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20030220322A1 (en) | 2003-11-27 |
DE10050661A1 (de) | 2002-04-18 |
RU2003113965A (ru) | 2004-12-10 |
AU2002214007A1 (en) | 2002-04-22 |
PE20020477A1 (es) | 2002-06-29 |
ECSP034554A (es) | 2003-05-26 |
EP1325010A1 (de) | 2003-07-09 |
NZ525651A (en) | 2004-10-29 |
CA2425685A1 (en) | 2003-04-11 |
ZA200303634B (en) | 2004-08-12 |
IL155379A0 (en) | 2003-11-23 |
HK1056558A1 (en) | 2004-02-20 |
CN1243753C (zh) | 2006-03-01 |
NO20031588D0 (no) | 2003-04-08 |
HUP0302606A3 (en) | 2007-03-28 |
ES2239168T3 (es) | 2005-09-16 |
MXPA03003199A (es) | 2004-03-18 |
AR035496A1 (es) | 2004-06-02 |
HUP0302606A2 (hu) | 2004-07-28 |
PL361777A1 (en) | 2004-10-04 |
EP1325010B1 (de) | 2005-04-27 |
KR20030036923A (ko) | 2003-05-09 |
WO2002030934A1 (de) | 2002-04-18 |
US7226924B2 (en) | 2007-06-05 |
CN1469879A (zh) | 2004-01-21 |
NO20031588L (no) | 2003-04-08 |
JP2004511485A (ja) | 2004-04-15 |
ATE294180T1 (de) | 2005-05-15 |
DE50106048D1 (de) | 2005-06-02 |
BR0114735A (pt) | 2003-10-14 |
SK4152003A3 (en) | 2003-10-07 |
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