PT1325010E - 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas - Google Patents

3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas

Info

Publication number
PT1325010E
PT1325010E PT01982417T PT01982417T PT1325010E PT 1325010 E PT1325010 E PT 1325010E PT 01982417 T PT01982417 T PT 01982417T PT 01982417 T PT01982417 T PT 01982417T PT 1325010 E PT1325010 E PT 1325010E
Authority
PT
Portugal
Prior art keywords
pyrimidines
dihydropyrimido
dihydropyrazine
replaced
pyrimidines replaced
Prior art date
Application number
PT01982417T
Other languages
English (en)
Inventor
Corinna Maul
Matthias Gerlach
Utz-Peter Jagusch
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PT1325010E publication Critical patent/PT1325010E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT01982417T 2000-10-13 2001-10-10 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas PT1325010E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10050661A DE10050661A1 (de) 2000-10-13 2000-10-13 Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine

Publications (1)

Publication Number Publication Date
PT1325010E true PT1325010E (pt) 2005-08-31

Family

ID=7659596

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01982417T PT1325010E (pt) 2000-10-13 2001-10-10 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas

Country Status (26)

Country Link
US (1) US7226924B2 (pt)
EP (1) EP1325010B1 (pt)
JP (1) JP2004511485A (pt)
KR (1) KR20030036923A (pt)
CN (1) CN1243753C (pt)
AR (1) AR035496A1 (pt)
AT (1) ATE294180T1 (pt)
AU (1) AU2002214007A1 (pt)
BR (1) BR0114735A (pt)
CA (1) CA2425685A1 (pt)
DE (2) DE10050661A1 (pt)
EC (1) ECSP034554A (pt)
ES (1) ES2239168T3 (pt)
HK (1) HK1056558A1 (pt)
HU (1) HUP0302606A3 (pt)
IL (1) IL155379A0 (pt)
MX (1) MXPA03003199A (pt)
NO (1) NO20031588L (pt)
NZ (1) NZ525651A (pt)
PE (1) PE20020477A1 (pt)
PL (1) PL361777A1 (pt)
PT (1) PT1325010E (pt)
RU (1) RU2003113965A (pt)
SK (1) SK4152003A3 (pt)
WO (1) WO2002030934A1 (pt)
ZA (1) ZA200303634B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005316668B2 (en) 2004-12-13 2012-09-06 Millennium Pharmaceuticals, Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558618A (en) * 1968-04-01 1971-01-26 Dow Chemical Co Novel 4h-pyrazino(1,2-a)pyrimidine-4-ones
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
HU178910B (en) * 1977-08-19 1982-07-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
JP2668259B2 (ja) * 1988-02-18 1997-10-27 塩野義製薬株式会社 複素環化合物および抗潰瘍剤
FI94531C (fi) * 1990-03-13 1995-09-25 Ime Intermed Enterpris Sa Menetelmä farmaseuttisesti aktiivisen 1,3,4,6,7,8-heksahydro-2H-pyrimido-(1,2-a)-pyrimidiinijohdannaisen valmistamiseksi
IT1263804B (it) * 1993-01-22 1996-09-03 Luso Farmaco Inst Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
EP0795555A4 (en) * 1995-09-28 1998-01-07 Otsuka Pharma Co Ltd ANALGETICS

Also Published As

Publication number Publication date
US20030220322A1 (en) 2003-11-27
DE10050661A1 (de) 2002-04-18
RU2003113965A (ru) 2004-12-10
AU2002214007A1 (en) 2002-04-22
PE20020477A1 (es) 2002-06-29
ECSP034554A (es) 2003-05-26
EP1325010A1 (de) 2003-07-09
NZ525651A (en) 2004-10-29
CA2425685A1 (en) 2003-04-11
ZA200303634B (en) 2004-08-12
IL155379A0 (en) 2003-11-23
HK1056558A1 (en) 2004-02-20
CN1243753C (zh) 2006-03-01
NO20031588D0 (no) 2003-04-08
HUP0302606A3 (en) 2007-03-28
ES2239168T3 (es) 2005-09-16
MXPA03003199A (es) 2004-03-18
AR035496A1 (es) 2004-06-02
HUP0302606A2 (hu) 2004-07-28
PL361777A1 (en) 2004-10-04
EP1325010B1 (de) 2005-04-27
KR20030036923A (ko) 2003-05-09
WO2002030934A1 (de) 2002-04-18
US7226924B2 (en) 2007-06-05
CN1469879A (zh) 2004-01-21
NO20031588L (no) 2003-04-08
JP2004511485A (ja) 2004-04-15
ATE294180T1 (de) 2005-05-15
DE50106048D1 (de) 2005-06-02
BR0114735A (pt) 2003-10-14
SK4152003A3 (en) 2003-10-07

Similar Documents

Publication Publication Date Title
NO20021694L (no) Pyrazolo[4,3-d]pyrimidinderivater
DE69915675D1 (de) Triazolo[4,5-d]pyrimidin-derivate
PT1140939E (pt) 2-aril-3-(heteroaril)- imidazo [1,2-alfa] pirimidinas substituidas, e formulacoes farmaceuticas e metodos relacionados
DE60104671D1 (de) Imidazopyrimidin-derivate und triazolopyrimidin-derivate
ZA200205097B (en) N-(5,7-dimethoxy[1,2,4]triazolo[1,5-A]pyrimidin-2-yl) arylsulfonamide compounds and their use as herbicides.
DE69804273D1 (de) 5h-Thiazolo[3,2-a]pyrimidinderivate
IL185461A0 (en) Pyrimidine compounds and their use
DE60103909D1 (de) 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-on- und 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5 1honderivate
DK1210349T3 (da) Pyrazolo[4,3-d]pyrimidiner
DE60135797D1 (de) Kunstleder
PT1325010E (pt) 3, 4-di-hidropirimido [1,2-a] pirimidinas e 3, 4-di-hidropirazino [1,2-a] pirimidinas substituidas
ATA175298A (de) Sitzeinrichtung
NO20026246L (no) 2-aminoalkyl-tieno[2,3-d]pyrimidiner
PT1326866E (pt) 3,4-di-hidropirido[1,2-a]pirimidinas substituidas
FI19992468A (fi) Tuoli
IS6073A (is) Axlarsæti
ATA90082000A (de) Sitzmöbel
DK1325010T3 (da) Substituerede 3,4-dihydro-pyrimido[1,2-a]pyrimidiner og 3,4-dihydro-pyrazino[1,2-a]pyrimidiner
DK1326866T3 (da) Substituerede 3,4-dihydro-pyrido[1,2-a]pyrimidiner
DK199800457U3 (da) Rullende armstøtte
SI1325010T1 (en) Substituted 3.4-dihydro-pyrimido (1,2-a)pyrimidines and 3.4-dihydropyrazino (1,2-a)pyrimidines
IT244576Y1 (it) Sedia ripiegabile
IT244577Y1 (it) Sedia ripiegabile
FI4027U1 (fi) Tuoli
FI3553U1 (fi) Tuoli