HK1054745A1 - Processes for the preparation of carbapenem-type antibacterial agents - Google Patents

Processes for the preparation of carbapenem-type antibacterial agents

Info

Publication number
HK1054745A1
HK1054745A1 HK03107007A HK03107007A HK1054745A1 HK 1054745 A1 HK1054745 A1 HK 1054745A1 HK 03107007 A HK03107007 A HK 03107007A HK 03107007 A HK03107007 A HK 03107007A HK 1054745 A1 HK1054745 A1 HK 1054745A1
Authority
HK
Hong Kong
Prior art keywords
preparation
carbapenem
processes
type antibacterial
antibacterial agents
Prior art date
Application number
HK03107007A
Other languages
English (en)
Inventor
Katsuhiko Fujimoto
Takashi Kasai
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HK1054745A1 publication Critical patent/HK1054745A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK03107007A 2000-11-20 2003-09-29 Processes for the preparation of carbapenem-type antibacterial agents HK1054745A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000352178 2000-11-20
PCT/JP2001/010096 WO2002040482A1 (fr) 2000-11-20 2001-11-19 Procede de production d'un antibacterien de type carbapenem

Publications (1)

Publication Number Publication Date
HK1054745A1 true HK1054745A1 (en) 2003-12-12

Family

ID=18825114

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03107007A HK1054745A1 (en) 2000-11-20 2003-09-29 Processes for the preparation of carbapenem-type antibacterial agents

Country Status (15)

Country Link
US (2) US7034150B2 (da)
EP (1) EP1338596B1 (da)
KR (1) KR100825243B1 (da)
CN (1) CN1247581C (da)
AT (1) ATE315568T1 (da)
AU (1) AU2002214325A1 (da)
CA (1) CA2429071A1 (da)
CY (1) CY1105598T1 (da)
DE (1) DE60116656T2 (da)
DK (1) DK1338596T3 (da)
ES (1) ES2256311T3 (da)
HK (1) HK1054745A1 (da)
PT (1) PT1338596E (da)
TW (1) TWI290925B (da)
WO (1) WO2002040482A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2602097A1 (en) * 2005-03-22 2006-09-28 Daiichi Sankyo Company, Limited Process for producing carbapenem derivatives having 1-alkylpyrrolidine structure
CN101328178B (zh) * 2007-06-15 2010-10-13 山东轩竹医药科技有限公司 含有噻吩取代的巯基吡咯烷的培南衍生物
CN101357919B (zh) * 2007-06-22 2011-06-15 山东轩竹医药科技有限公司 含有巯基吡咯烷甲酰胺苯磺酰基的培南衍生物
CN101333219B (zh) * 2007-06-26 2010-10-13 山东轩竹医药科技有限公司 含有巯基吡咯烷甲酰胺苯烷基杂环的培南衍生物
CN101367812B (zh) * 2007-06-28 2011-04-27 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰胺基环戊烯酸取代的培南衍生物
CN101343271B (zh) * 2007-07-13 2011-01-12 山东轩竹医药科技有限公司 含有异噁唑烷酮的培南衍生物
EP2506897B1 (en) * 2009-12-04 2023-05-31 Becton, Dickinson and Company Pen needle removal device for a drug delivery device
CN102002069A (zh) * 2010-11-12 2011-04-06 上海巴迪生物医药科技有限公司 一种合成培南类侧链的双环中间体的制备方法及其应用
ES2785313T3 (es) * 2013-01-15 2020-10-06 Merck Patent Gmbh Acilguanidinas para el tratamiento de la artrosis

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
US4958029A (en) * 1987-01-13 1990-09-18 Banyu Pharmaceutical Co., Ltd. Process for the production of isoindoline derivatives, novel intermediates and process for their production
GB8809736D0 (en) * 1988-04-25 1988-06-02 Fujisawa Pharmaceutical Co New cephem compounds & process for preparation thereof
JP3091297B2 (ja) * 1992-01-10 2000-09-25 住友製薬株式会社 ピロリジン誘導体およびその製造方法
NZ324447A (en) 1995-12-21 1999-08-30 Sankyo Co 1-methyl-carbapenem substituted by a 4-pyrrolidinylthio group and medicaments
US5952338A (en) * 1996-07-05 1999-09-14 Takeda Chemical Industries, Ltd. Agent for prophylaxis and treatment of disturbance of visual function
JP2955276B2 (ja) 1997-06-19 1999-10-04 三共株式会社 １−メチルカルバペネム誘導体を含有する抗菌剤
US6063931A (en) * 1997-07-09 2000-05-16 Merck & Co., Inc. Process for synthesizing carbapenem side chain intermediates
EP1019411A4 (en) * 1997-07-09 2003-08-13 Merck & Co Inc METHOD FOR PRODUCING INTERMEDIATE PRODUCTS FOR CARBAPENEM SIDE CHAINS
JP4548335B2 (ja) * 2003-03-07 2010-09-22 味の素株式会社 腸管細胞のインスリン産生細胞への変換誘導剤、及び糖尿病治療剤

Also Published As

Publication number Publication date
ES2256311T3 (es) 2006-07-16
EP1338596A1 (en) 2003-08-27
EP1338596B1 (en) 2006-01-11
US7091363B2 (en) 2006-08-15
EP1338596A4 (en) 2004-08-04
PT1338596E (pt) 2006-05-31
DK1338596T3 (da) 2006-04-18
US20060009508A1 (en) 2006-01-12
CN1247581C (zh) 2006-03-29
CA2429071A1 (en) 2002-05-23
CY1105598T1 (el) 2010-07-28
DE60116656D1 (de) 2006-04-06
US7034150B2 (en) 2006-04-25
KR100825243B1 (ko) 2008-04-25
WO2002040482A1 (fr) 2002-05-23
DE60116656T2 (de) 2006-09-21
CN1486316A (zh) 2004-03-31
KR20030097793A (ko) 2003-12-31
AU2002214325A1 (en) 2002-05-27
US20030225055A1 (en) 2003-12-04
ATE315568T1 (de) 2006-02-15
TWI290925B (en) 2007-12-11

Similar Documents

Publication Publication Date Title
IL143314A0 (en) IMIDAZO [4, 5-b] PYRIDINIUMMETHYL-CONTAINING CEPHEM COMPOUNDS HAVING BROAD ANTIBACTERIAL SPECTRUM
EP0698606A4 (da)
AU3599701A (en) Fluorescent probes for the quantitation of zinc
HK1012341A1 (en) Pyrrolocarbazole
CY1105598T1 (el) Μεθοδοι για την παρασκευη αντιβακτηριακων παραγοντων τυπου carbapenem
EP1454903A4 (en) THIADIAZOLINDERIVAT
DE60223227T8 (de) Benzo[b]thiophenderivate und Verfahren zu deren Herstellung
PE23396A1 (es) Benzotiofeno de glucopiranosido
MY103393A (en) 4-oxo-3-quinolinecarboxylic acids useful as antibacterial agents and preparation thereof
GB9811050D0 (en) Pyrazoles
HU9601701D0 (en) Aromatic hydroxamic acid compounds, process for producing them and their use
EP1557407A4 (en) NEW ALPHA-CETOAMIDE DERIVATIVE AND USE THEREOF
WO2002051822A3 (en) Isothiazolecarboxamides as microbicides
PL345549A1 (en) Polyhydroalkylpyrazine derivatives and their preparation and medicines containing them
GT199400033A (es) Compuestos antibacteriales (derivados de cefalosporina)

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111119