HK1052881B - 取代的吡唑類化合物用於治療過敏的應用 - Google Patents
取代的吡唑類化合物用於治療過敏的應用Info
- Publication number
- HK1052881B HK1052881B HK03105185.1A HK03105185A HK1052881B HK 1052881 B HK1052881 B HK 1052881B HK 03105185 A HK03105185 A HK 03105185A HK 1052881 B HK1052881 B HK 1052881B
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- allergies
- substituted pyrazoles
- pyrazoles
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23040700P | 2000-09-06 | 2000-09-06 | |
US09/927,188 US6635633B2 (en) | 2000-08-14 | 2001-08-10 | Substituted pyrazoles |
PCT/US2001/027480 WO2002020013A2 (en) | 2000-09-06 | 2001-09-05 | A method for treating allergies using substituted pyrazoles |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1052881A1 HK1052881A1 (en) | 2003-10-03 |
HK1052881B true HK1052881B (zh) | 2009-01-30 |
Family
ID=26924202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03105185.1A HK1052881B (zh) | 2000-09-06 | 2003-07-17 | 取代的吡唑類化合物用於治療過敏的應用 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1315492B1 (zh) |
JP (1) | JP4129391B2 (zh) |
CN (1) | CN1321641C (zh) |
AT (1) | ATE402699T1 (zh) |
AU (2) | AU8873101A (zh) |
CA (1) | CA2421510A1 (zh) |
DE (1) | DE60135130D1 (zh) |
DK (1) | DK1315492T3 (zh) |
ES (1) | ES2309088T3 (zh) |
HK (1) | HK1052881B (zh) |
MX (1) | MXPA03001962A (zh) |
NZ (1) | NZ524682A (zh) |
PT (1) | PT1315492E (zh) |
WO (1) | WO2002020013A2 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2421493A1 (en) * | 2000-09-06 | 2002-03-14 | Ortho-Mcneil Pharmaceutical, Inc. | A method for treating allergies using substituted pyrazoles |
ES2201899B1 (es) * | 2002-04-01 | 2005-06-01 | Almirall Prodesfarma, S.A. | Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos. |
ES2201907B1 (es) | 2002-05-29 | 2005-06-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos. |
DE602005010698D1 (de) | 2004-06-09 | 2008-12-11 | Glaxo Group Ltd | Pyrrolopyridinderivate |
PE20120508A1 (es) | 2009-06-17 | 2012-05-09 | Vertex Pharma | Inhibidores de la replicacion de los virus de la gripe |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
JP6133291B2 (ja) | 2011-08-12 | 2017-05-24 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | ピラゾロ[3,4−c]ピリジン化合物と使用方法 |
SG10201804021TA (en) | 2013-11-13 | 2018-07-30 | Vertex Pharma | Methods of preparing inhibitors of influenza viruses replication |
EP3068776B1 (en) | 2013-11-13 | 2019-05-29 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤 |
WO2016183116A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
DK3860998T3 (da) | 2018-10-05 | 2024-03-25 | Annapurna Bio Inc | Forbindelser og sammensætninger til behandlinger af tilstande, der er forbundet med APJ-receptoraktivitet |
CN111518019B (zh) * | 2019-02-01 | 2023-10-24 | 江苏豪森药业集团有限公司 | 一种棕榈酸帕里哌酮中间体的制备方法 |
CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789948A (fr) * | 1971-10-13 | 1973-04-11 | Sandoz Sa | Nouveaux derives du pyrazole, leur preparation et leur application comme medicaments |
JPH0615542B2 (ja) * | 1986-07-22 | 1994-03-02 | 吉富製薬株式会社 | ピラゾロピリジン化合物 |
JP3907220B2 (ja) * | 1994-06-30 | 2007-04-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 複素環含有化合物 |
JP3964478B2 (ja) * | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
AU7553198A (en) * | 1997-06-12 | 1998-12-30 | Sumitomo Pharmaceuticals Company, Limited | Pyrazole derivatives |
-
2001
- 2001-09-05 AU AU8873101A patent/AU8873101A/xx active Pending
- 2001-09-05 MX MXPA03001962A patent/MXPA03001962A/es active IP Right Grant
- 2001-09-05 DE DE60135130T patent/DE60135130D1/de not_active Expired - Lifetime
- 2001-09-05 AU AU2001288731A patent/AU2001288731B8/en not_active Expired
- 2001-09-05 EP EP01968487A patent/EP1315492B1/en not_active Expired - Lifetime
- 2001-09-05 DK DK01968487T patent/DK1315492T3/da active
- 2001-09-05 NZ NZ524682A patent/NZ524682A/en unknown
- 2001-09-05 JP JP2002524497A patent/JP4129391B2/ja not_active Expired - Fee Related
- 2001-09-05 PT PT01968487T patent/PT1315492E/pt unknown
- 2001-09-05 CA CA002421510A patent/CA2421510A1/en not_active Abandoned
- 2001-09-05 CN CNB018185045A patent/CN1321641C/zh not_active Expired - Lifetime
- 2001-09-05 AT AT01968487T patent/ATE402699T1/de not_active IP Right Cessation
- 2001-09-05 WO PCT/US2001/027480 patent/WO2002020013A2/en active IP Right Grant
- 2001-09-05 ES ES01968487T patent/ES2309088T3/es not_active Expired - Lifetime
-
2003
- 2003-07-17 HK HK03105185.1A patent/HK1052881B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE60135130D1 (de) | 2008-09-11 |
DK1315492T3 (da) | 2008-10-13 |
NZ524682A (en) | 2004-11-26 |
EP1315492B1 (en) | 2008-07-30 |
PT1315492E (pt) | 2008-10-01 |
WO2002020013A3 (en) | 2002-06-20 |
CN1505509A (zh) | 2004-06-16 |
AU8873101A (en) | 2002-03-22 |
CN1321641C (zh) | 2007-06-20 |
HK1052881A1 (en) | 2003-10-03 |
EP1315492A2 (en) | 2003-06-04 |
CA2421510A1 (en) | 2002-03-14 |
ES2309088T3 (es) | 2008-12-16 |
WO2002020013A2 (en) | 2002-03-14 |
AU2001288731B2 (en) | 2005-12-15 |
JP4129391B2 (ja) | 2008-08-06 |
MXPA03001962A (es) | 2004-03-26 |
JP2004508330A (ja) | 2004-03-18 |
AU2001288731B8 (en) | 2006-04-13 |
ATE402699T1 (de) | 2008-08-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1053794A1 (en) | A method for treating allergies using substituted pyrazoles | |
HK1052881A1 (en) | Use of substituted pyrazoles for the treatment of allergies | |
ZA200302637B (en) | A method for treating allergies using substituted pyrazoles. | |
HK1051499A1 (en) | Method for treating ocular pain | |
MXPA03002861A (es) | Nuevos retinoides para tratamiento del enfisema. | |
ZA200404752B (en) | 6-aminomorphinane derivatives method for the production and use thereof | |
MXPA03001717A (es) | METODO PARA EL TRATAMIENTO DE LA MIGRAnA. | |
HK1064261A1 (en) | Method for the treatment of tobacco. | |
NL1021504A1 (nl) | Waterstofbehandelingsproces. | |
WO2003072541A3 (en) | Chemical compounds | |
TW200510323A (en) | Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives | |
ITGE20020050A0 (it) | Procedimento per il trattamento di filati mediante agugliatura. | |
HK1053606A1 (en) | Use of substituted pyrazoles for the manufacture of a medicament for the treatment of allergies | |
GB0102408D0 (en) | Chemical compounds | |
WO2001078651A3 (en) | Method for treating neoplasmin with topoisomase i inhibitor | |
AU2002366617A1 (en) | Device for treating headache | |
AU2002325277A1 (en) | Apparatus for physiotherapic hyperthermia treatments | |
IT1317066B1 (it) | Uso di derivati dell'acido cinnamico come agenti insetticidi. | |
AU2002317257A1 (en) | Cosmetic treatment method for stretch marks | |
AU2002345272A1 (en) | Apparatus for treating organic tissues | |
AR022625A1 (es) | Metodo de transformacion de soja. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120905 |