HK1050181B - 降低2-二甲氨基-1-苯基-3-環己烯-1-羧酸乙酯溶液中3-二甲氨基-2-苯基丙酸乙酯含量的方法 - Google Patents
降低2-二甲氨基-1-苯基-3-環己烯-1-羧酸乙酯溶液中3-二甲氨基-2-苯基丙酸乙酯含量的方法Info
- Publication number
- HK1050181B HK1050181B HK03101980.7A HK03101980A HK1050181B HK 1050181 B HK1050181 B HK 1050181B HK 03101980 A HK03101980 A HK 03101980A HK 1050181 B HK1050181 B HK 1050181B
- Authority
- HK
- Hong Kong
- Prior art keywords
- dimethylamino
- ethyl ester
- acid ethyl
- cyclohexene
- phenyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 2
- 125000004494 ethyl ester group Chemical group 0.000 title 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title 1
- WDEFBBTXULIOBB-UHFFFAOYSA-N ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate Chemical compound C=1C=CC=CC=1C1(C(=O)OCC)CCC=CC1N(C)C WDEFBBTXULIOBB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- WYVAVFURKHCMTG-UHFFFAOYSA-N ethyl 3-(dimethylamino)-2-phenylpropanoate Chemical compound CCOC(=O)C(CN(C)C)C1=CC=CC=C1 WYVAVFURKHCMTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19902590A DE19902590A1 (de) | 1999-01-22 | 1999-01-22 | Verfahren zur Reduktion des an 3-Dimethylamino-2-phenylpropionsäureethylester-Gehalts in Lösungen von 2-Dimethylamino-1-phenyl-3-cyclohexen-1-carbonsäureehtylester |
| PCT/EP2000/000306 WO2000043353A1 (de) | 1999-01-22 | 2000-01-15 | Verfahren zur reduktion des 3-dimethylamino-2-phenylpropionsäure- ethylester-gehalts in lösungen von 2-dimethylamino -1-phenyl -3- cyclohexen-1-carbonsäureethylester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1050181A1 HK1050181A1 (en) | 2003-06-13 |
| HK1050181B true HK1050181B (zh) | 2005-09-09 |
Family
ID=7895156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK03101980.7A HK1050181B (zh) | 1999-01-22 | 2003-03-18 | 降低2-二甲氨基-1-苯基-3-環己烯-1-羧酸乙酯溶液中3-二甲氨基-2-苯基丙酸乙酯含量的方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7273947B1 (zh) |
| EP (1) | EP1144361B1 (zh) |
| JP (1) | JP3635032B2 (zh) |
| KR (1) | KR20010102987A (zh) |
| CN (1) | CN1177805C (zh) |
| AT (1) | ATE273947T1 (zh) |
| AU (1) | AU766196B2 (zh) |
| BR (1) | BR0007646A (zh) |
| CA (1) | CA2359080C (zh) |
| CZ (1) | CZ20012602A3 (zh) |
| DE (2) | DE19902590A1 (zh) |
| ES (1) | ES2226777T3 (zh) |
| HK (1) | HK1050181B (zh) |
| HU (1) | HUP0200531A3 (zh) |
| IL (2) | IL144203A0 (zh) |
| MX (1) | MXPA01007249A (zh) |
| NO (1) | NO20013528L (zh) |
| RU (1) | RU2201918C1 (zh) |
| TW (1) | TW462958B (zh) |
| WO (1) | WO2000043353A1 (zh) |
| ZA (1) | ZA200105537B (zh) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1768704B1 (de) * | 1968-06-21 | 1971-11-11 | Goedecke Ag | Verfahren zur Abtrennung von 3-trans-Dimethylamino-4-phenyl-4-trans-carbaethoxy-delta?-cyclohexen |
| US3679732A (en) * | 1969-04-17 | 1972-07-25 | Warner Lambert Co | Process for obtaining 3-trans-dimethylamino-4-phenyl-4-trans-carbethoxy-{66 {11 -cyclohexene |
| DE2261462B1 (de) * | 1972-12-15 | 1974-04-25 | Goedecke Ag | Verfahren zur Abtrennung von (+)-3r-N-Dimethylamino-4c-phenyl-4t-aethoxycarbonyl-cyclohexen-(1) |
-
1999
- 1999-01-22 DE DE19902590A patent/DE19902590A1/de not_active Withdrawn
- 1999-12-16 TW TW088122113A patent/TW462958B/zh not_active IP Right Cessation
-
2000
- 2000-01-15 EP EP00902598A patent/EP1144361B1/de not_active Expired - Lifetime
- 2000-01-15 WO PCT/EP2000/000306 patent/WO2000043353A1/de active IP Right Grant
- 2000-01-15 CA CA002359080A patent/CA2359080C/en not_active Expired - Fee Related
- 2000-01-15 BR BR0007646-5A patent/BR0007646A/pt not_active IP Right Cessation
- 2000-01-15 ES ES00902598T patent/ES2226777T3/es not_active Expired - Lifetime
- 2000-01-15 HU HU0200531A patent/HUP0200531A3/hu unknown
- 2000-01-15 KR KR1020017009188A patent/KR20010102987A/ko active IP Right Grant
- 2000-01-15 AU AU24376/00A patent/AU766196B2/en not_active Ceased
- 2000-01-15 US US09/889,383 patent/US7273947B1/en not_active Expired - Fee Related
- 2000-01-15 CN CNB008029539A patent/CN1177805C/zh not_active Expired - Fee Related
- 2000-01-15 RU RU2001123589/04A patent/RU2201918C1/ru not_active IP Right Cessation
- 2000-01-15 CZ CZ20012602A patent/CZ20012602A3/cs unknown
- 2000-01-15 MX MXPA01007249A patent/MXPA01007249A/es not_active IP Right Cessation
- 2000-01-15 JP JP2000594771A patent/JP3635032B2/ja not_active Expired - Fee Related
- 2000-01-15 AT AT00902598T patent/ATE273947T1/de not_active IP Right Cessation
- 2000-01-15 DE DE50007472T patent/DE50007472D1/de not_active Expired - Lifetime
- 2000-01-15 IL IL14420300A patent/IL144203A0/xx active IP Right Grant
-
2001
- 2001-07-05 ZA ZA200105537A patent/ZA200105537B/en unknown
- 2001-07-09 IL IL144203A patent/IL144203A/en not_active IP Right Cessation
- 2001-07-17 NO NO20013528A patent/NO20013528L/no not_active Application Discontinuation
-
2003
- 2003-03-18 HK HK03101980.7A patent/HK1050181B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2201918C1 (ru) | 2003-04-10 |
| WO2000043353A1 (de) | 2000-07-27 |
| BR0007646A (pt) | 2001-10-16 |
| AU766196B2 (en) | 2003-10-09 |
| JP2002535303A (ja) | 2002-10-22 |
| CN1177805C (zh) | 2004-12-01 |
| CZ20012602A3 (cs) | 2003-01-15 |
| EP1144361A1 (de) | 2001-10-17 |
| EP1144361B1 (de) | 2004-08-18 |
| IL144203A (en) | 2008-08-07 |
| NO20013528D0 (no) | 2001-07-17 |
| US7273947B1 (en) | 2007-09-25 |
| HUP0200531A3 (en) | 2004-03-29 |
| KR20010102987A (ko) | 2001-11-17 |
| ES2226777T3 (es) | 2005-04-01 |
| DE19902590A1 (de) | 2000-07-27 |
| CA2359080A1 (en) | 2000-07-27 |
| CA2359080C (en) | 2005-06-14 |
| HK1050181A1 (en) | 2003-06-13 |
| ATE273947T1 (de) | 2004-09-15 |
| ZA200105537B (en) | 2002-07-05 |
| MXPA01007249A (es) | 2002-06-04 |
| IL144203A0 (en) | 2002-05-23 |
| NO20013528L (no) | 2001-07-17 |
| JP3635032B2 (ja) | 2005-03-30 |
| AU2437600A (en) | 2000-08-07 |
| CN1373746A (zh) | 2002-10-09 |
| DE50007472D1 (de) | 2004-09-23 |
| TW462958B (en) | 2001-11-11 |
| HUP0200531A2 (en) | 2002-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20090115 |