HK1049350B - Multipotent adult stem cells and methods for isolation - Google Patents

Multipotent adult stem cells and methods for isolation Download PDF

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Publication number
HK1049350B
HK1049350B HK02109304.0A HK02109304A HK1049350B HK 1049350 B HK1049350 B HK 1049350B HK 02109304 A HK02109304 A HK 02109304A HK 1049350 B HK1049350 B HK 1049350B
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Hong Kong
Prior art keywords
cells
cell
mascs
differentiation
human
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HK02109304.0A
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German (de)
English (en)
French (fr)
Chinese (zh)
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HK1049350A1 (en
Inventor
Leo T. Furcht
Catherine M. Verfaillie
Morayma Reyes
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Abt Holding Company
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Publication of HK1049350A1 publication Critical patent/HK1049350A1/en
Publication of HK1049350B publication Critical patent/HK1049350B/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/414—Nervous system antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2503/00—Use of cells in diagnostics
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2510/00—Genetically modified cells

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  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK02109304.0A 1999-08-05 2000-08-04 Multipotent adult stem cells and methods for isolation HK1049350B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14732499P 1999-08-05 1999-08-05
US147324P 1999-08-05
US16465099P 1999-11-10 1999-11-10
US164650P 1999-11-10
PCT/US2000/021387 WO2001011011A2 (en) 1999-08-05 2000-08-04 Multipotent adult stem cells and methods for isolation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK11109095.2A Division HK1154894A (en) 1999-08-05 2002-12-23 Multipotent adult stem cells and methods for isolation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK11109095.2A Addition HK1154894A (en) 1999-08-05 2002-12-23 Multipotent adult stem cells and methods for isolation

Publications (2)

Publication Number Publication Date
HK1049350A1 HK1049350A1 (en) 2003-05-09
HK1049350B true HK1049350B (en) 2012-01-27

Family

ID=26844814

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02109304.0A HK1049350B (en) 1999-08-05 2000-08-04 Multipotent adult stem cells and methods for isolation

Country Status (11)

Country Link
US (1) US10006004B2 (https=)
EP (2) EP1226233B1 (https=)
JP (9) JP5398941B2 (https=)
AT (1) ATE514772T1 (https=)
CA (2) CA2381292C (https=)
DK (1) DK1226233T3 (https=)
HK (1) HK1049350B (https=)
IL (4) IL147990A0 (https=)
NZ (1) NZ517002A (https=)
PT (1) PT1226233E (https=)
WO (1) WO2001011011A2 (https=)

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