HK1047539B - 微顆粒 - Google Patents
微顆粒Info
- Publication number
- HK1047539B HK1047539B HK02108837.8A HK02108837A HK1047539B HK 1047539 B HK1047539 B HK 1047539B HK 02108837 A HK02108837 A HK 02108837A HK 1047539 B HK1047539 B HK 1047539B
- Authority
- HK
- Hong Kong
- Prior art keywords
- microparticles
- organic solvent
- total weight
- active agent
- less
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64391996A | 1996-05-07 | 1996-05-07 | |
HK99101960A HK1016884A1 (en) | 1996-05-07 | 1999-04-30 | Process for the preparation of microparticles |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1047539A1 HK1047539A1 (en) | 2003-02-28 |
HK1047539B true HK1047539B (zh) | 2007-08-24 |
Family
ID=24582704
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02108837.8A HK1047539B (zh) | 1996-05-07 | 1999-04-30 | 微顆粒 |
HK99101960A HK1016884A1 (en) | 1996-05-07 | 1999-04-30 | Process for the preparation of microparticles |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99101960A HK1016884A1 (en) | 1996-05-07 | 1999-04-30 | Process for the preparation of microparticles |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1210942B1 (zh) |
AT (2) | ATE357218T1 (zh) |
CY (1) | CY2318B1 (zh) |
DE (2) | DE69715191T2 (zh) |
DK (2) | DK0904063T3 (zh) |
ES (2) | ES2284776T3 (zh) |
HK (2) | HK1047539B (zh) |
MY (1) | MY118174A (zh) |
PT (2) | PT1210942E (zh) |
SI (2) | SI1210942T1 (zh) |
TR (1) | TR199802258T2 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
US20050048126A1 (en) | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
BR0212833A (pt) | 2001-09-26 | 2004-10-13 | Baxter Int | Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
CN101677952B (zh) | 2007-05-18 | 2012-12-05 | 杜雷科特公司 | 改进的贮库制剂 |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
NZ581862A (en) | 2007-05-25 | 2012-06-29 | Tolmar Therapeutics Inc | Injectable subcutaneous formulation comprising risperidone capable of forming a solid, microporous implant in a patient |
US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
BR112015022023B1 (pt) | 2013-03-11 | 2022-12-06 | Durect Corporation | Composição de liberação controlada injetável compreendendo transportador líquido de alta viscosidade |
CN104226191B (zh) * | 2014-09-01 | 2017-04-19 | 南京理工大学 | 乙基纤维素多孔颗粒的常温制备方法 |
EP3784705A4 (en) * | 2018-04-23 | 2022-03-02 | Graybug Vision, Inc. | IMPROVED CONTINUOUS PRODUCTION OF MICROPARTICLES |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4389330A (en) * | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
US5478564A (en) * | 1990-02-22 | 1995-12-26 | Teva Pharmaceutical Industries, Ltd. | Preparation of microparticles for controlled release of water-soluble substances |
FR2693905B1 (fr) * | 1992-07-27 | 1994-09-02 | Rhone Merieux | Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues. |
DK0669128T3 (da) * | 1992-11-17 | 2000-06-19 | Yoshitomi Pharmaceutical | Sustained-release mikrosfære indeholdende antipsykotikum og fremgangsmåde til at fremstille samme |
DE69415684T2 (de) * | 1993-10-22 | 1999-06-10 | Genentech Inc., San Francisco, Calif. | Verfahren zur herstellung von mikrospharen mit einer wirbelschichtstufe |
EP1649850A1 (en) * | 1993-11-19 | 2006-04-26 | Alkermes Controlled Therapeutics Inc. II | Preparation of biodegradable microparticles containing a biologically active agent |
JP3645906B2 (ja) * | 1993-11-19 | 2005-05-11 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | マイクロカプセル封入された3−ピペリジニル−置換1,2−ベンズイソオキサゾール類及び1,2−ベンズイソチアゾール類 |
-
1997
- 1997-05-06 ES ES02075905T patent/ES2284776T3/es not_active Expired - Lifetime
- 1997-05-06 AT AT02075905T patent/ATE357218T1/de active
- 1997-05-06 PT PT02075905T patent/PT1210942E/pt unknown
- 1997-05-06 AT AT97923063T patent/ATE223206T1/de active
- 1997-05-06 DE DE69715191T patent/DE69715191T2/de not_active Expired - Lifetime
- 1997-05-06 ES ES97923063T patent/ES2183172T3/es not_active Expired - Lifetime
- 1997-05-06 DK DK97923063T patent/DK0904063T3/da active
- 1997-05-06 DK DK02075905T patent/DK1210942T3/da active
- 1997-05-06 SI SI9730762T patent/SI1210942T1/sl unknown
- 1997-05-06 TR TR1998/02258T patent/TR199802258T2/xx unknown
- 1997-05-06 EP EP02075905A patent/EP1210942B1/en not_active Revoked
- 1997-05-06 PT PT97923063T patent/PT904063E/pt unknown
- 1997-05-06 MY MYPI97001990A patent/MY118174A/en unknown
- 1997-05-06 DE DE69737515T patent/DE69737515T2/de not_active Expired - Lifetime
- 1997-05-06 SI SI9730417T patent/SI0904063T1/xx unknown
-
1999
- 1999-04-30 HK HK02108837.8A patent/HK1047539B/zh not_active IP Right Cessation
- 1999-04-30 HK HK99101960A patent/HK1016884A1/xx not_active IP Right Cessation
-
2003
- 2003-01-16 CY CY0300017A patent/CY2318B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE69737515T2 (de) | 2007-12-06 |
SI0904063T1 (en) | 2003-02-28 |
ES2284776T3 (es) | 2007-11-16 |
HK1047539A1 (en) | 2003-02-28 |
SI1210942T1 (sl) | 2007-10-31 |
EP1210942A2 (en) | 2002-06-05 |
HK1016884A1 (en) | 1999-11-12 |
CY2318B1 (en) | 2003-11-14 |
DE69737515D1 (de) | 2007-05-03 |
ATE357218T1 (de) | 2007-04-15 |
EP1210942A3 (en) | 2004-05-26 |
DK0904063T3 (da) | 2002-12-16 |
MY118174A (en) | 2004-09-30 |
PT904063E (pt) | 2003-01-31 |
DE69715191T2 (de) | 2003-04-30 |
EP1210942B1 (en) | 2007-03-21 |
PT1210942E (pt) | 2007-06-26 |
DE69715191D1 (de) | 2002-10-10 |
ATE223206T1 (de) | 2002-09-15 |
DK1210942T3 (da) | 2007-07-23 |
ES2183172T3 (es) | 2003-03-16 |
TR199802258T2 (en) | 2001-11-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |
Effective date: 20170505 |