HK1046534A1 - 可溶性膜蛋白受體結構域的化學合成及應用 - Google Patents

可溶性膜蛋白受體結構域的化學合成及應用

Info

Publication number
HK1046534A1
HK1046534A1 HK02108186.5A HK02108186A HK1046534A1 HK 1046534 A1 HK1046534 A1 HK 1046534A1 HK 02108186 A HK02108186 A HK 02108186A HK 1046534 A1 HK1046534 A1 HK 1046534A1
Authority
HK
Hong Kong
Prior art keywords
chemical synthesis
membrane protein
protein receptor
soluble membrane
receptor domains
Prior art date
Application number
HK02108186.5A
Other languages
English (en)
Chinese (zh)
Inventor
G Kochendoerfer Gerd
Original Assignee
格萊風科學公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 格萊風科學公司 filed Critical 格萊風科學公司
Publication of HK1046534A1 publication Critical patent/HK1046534A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
HK02108186.5A 1999-03-11 2002-11-12 可溶性膜蛋白受體結構域的化學合成及應用 HK1046534A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12427299P 1999-03-11 1999-03-11
PCT/US2000/006297 WO2000053624A1 (fr) 1999-03-11 2000-03-09 Synthese chimique et utilisation de domaines de recepteurs de proteines membranaires solubles

Publications (1)

Publication Number Publication Date
HK1046534A1 true HK1046534A1 (zh) 2003-01-17

Family

ID=22413849

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02108186.5A HK1046534A1 (zh) 1999-03-11 2002-11-12 可溶性膜蛋白受體結構域的化學合成及應用

Country Status (7)

Country Link
EP (1) EP1159289A1 (fr)
JP (1) JP2002539136A (fr)
CN (1) CN1350544A (fr)
AU (1) AU768118B2 (fr)
CA (1) CA2372164A1 (fr)
HK (1) HK1046534A1 (fr)
WO (1) WO2000053624A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482425B2 (en) 1999-08-26 2009-01-27 Amylin Pharmaceuticals, Inc. Compositions for lipid matrix-assisted chemical ligation
EP1282699B1 (fr) 2000-05-04 2012-11-21 Sarepta Therapeutics, Inc. Composition anti-sens a region d'epissage et methode associee
US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
AU2006264567A1 (en) * 2005-05-05 2007-01-11 Valorisation Hsj, Societe En Commandite Cytokine receptor modulators and uses thereof
US7785834B2 (en) 2005-11-10 2010-08-31 Ercole Biotech, Inc. Soluble TNF receptors and their use in treatment of disease
WO2008051306A1 (fr) * 2006-10-20 2008-05-02 Ercole Biotech, Inc. Récepteurs de tnf solubles et leur utilisation pour le traitement de maladies
EP2709647B1 (fr) * 2011-02-23 2019-08-07 Massachusetts Institute Of Technology Protéines membranaires hydrosolubles et leurs procédés de préparation et d'utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7338294A (en) * 1993-07-20 1995-02-20 Bionebraska, Inc. Method for endomodification of proteins
ES2235336T3 (es) * 1997-06-13 2005-07-01 Gryphon Therapeutics, Inc. Ligacion quimica nativa en fase solida de peptidos desprotegidos o protegidos en la cisteina n-terminal en solucion acuosa.

Also Published As

Publication number Publication date
AU3874800A (en) 2000-09-28
EP1159289A1 (fr) 2001-12-05
WO2000053624A1 (fr) 2000-09-14
JP2002539136A (ja) 2002-11-19
CN1350544A (zh) 2002-05-22
CA2372164A1 (fr) 2000-09-14
AU768118B2 (en) 2003-12-04

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