AU768118B2 - Chemical synthesis and use of soluble membrane protein receptor domains - Google Patents

Chemical synthesis and use of soluble membrane protein receptor domains Download PDF

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Publication number
AU768118B2
AU768118B2 AU38748/00A AU3874800A AU768118B2 AU 768118 B2 AU768118 B2 AU 768118B2 AU 38748/00 A AU38748/00 A AU 38748/00A AU 3874800 A AU3874800 A AU 3874800A AU 768118 B2 AU768118 B2 AU 768118B2
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AU
Australia
Prior art keywords
receptor
extramembranous
domain
ligand
ligation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU38748/00A
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English (en)
Other versions
AU3874800A (en
Inventor
Gerd G. Kochendoerfer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gryphon Therapeutics Inc
Original Assignee
Gryphon Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gryphon Sciences filed Critical Gryphon Sciences
Publication of AU3874800A publication Critical patent/AU3874800A/en
Application granted granted Critical
Publication of AU768118B2 publication Critical patent/AU768118B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
AU38748/00A 1999-03-11 2000-03-09 Chemical synthesis and use of soluble membrane protein receptor domains Ceased AU768118B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12427299P 1999-03-11 1999-03-11
US60/124272 1999-03-11
PCT/US2000/006297 WO2000053624A1 (fr) 1999-03-11 2000-03-09 Synthese chimique et utilisation de domaines de recepteurs de proteines membranaires solubles

Publications (2)

Publication Number Publication Date
AU3874800A AU3874800A (en) 2000-09-28
AU768118B2 true AU768118B2 (en) 2003-12-04

Family

ID=22413849

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38748/00A Ceased AU768118B2 (en) 1999-03-11 2000-03-09 Chemical synthesis and use of soluble membrane protein receptor domains

Country Status (7)

Country Link
EP (1) EP1159289A1 (fr)
JP (1) JP2002539136A (fr)
CN (1) CN1350544A (fr)
AU (1) AU768118B2 (fr)
CA (1) CA2372164A1 (fr)
HK (1) HK1046534A1 (fr)
WO (1) WO2000053624A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482425B2 (en) 1999-08-26 2009-01-27 Amylin Pharmaceuticals, Inc. Compositions for lipid matrix-assisted chemical ligation
US6784291B2 (en) 2000-05-04 2004-08-31 Avi Biopharma, Inc. Splice-region antisense composition and method
US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
JP2008542685A (ja) * 2005-05-05 2008-11-27 ヴァロリザーシヨン・アッシュエスジ，ソシエテ・アン・コマンディット サイトカイン受容体修飾因子及びその使用
US7785834B2 (en) 2005-11-10 2010-08-31 Ercole Biotech, Inc. Soluble TNF receptors and their use in treatment of disease
AU2007309650A1 (en) * 2006-02-08 2008-05-02 Ercole Biotech, Inc. Soluble TNF receptors and their use in treatment of disease
WO2012116203A1 (fr) * 2011-02-23 2012-08-30 Massachusetts Institute Of Technology Protéines membranaires hydrosolubles et leurs procédés de préparation et d'utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003321A1 (fr) * 1993-07-20 1995-02-02 Bionebraska, Inc. Procede d'endomodification de proteins
EP1001968B1 (fr) * 1997-06-13 2004-12-22 Gryphon Therapeutics, Inc. Ligation chimique native en phase solide de peptides non proteges ou proteges en cysteine n-terminale dans une solution aqueuse

Also Published As

Publication number Publication date
AU3874800A (en) 2000-09-28
CA2372164A1 (fr) 2000-09-14
CN1350544A (zh) 2002-05-22
JP2002539136A (ja) 2002-11-19
HK1046534A1 (zh) 2003-01-17
EP1159289A1 (fr) 2001-12-05
WO2000053624A1 (fr) 2000-09-14

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