HK1046133B - 藥物化合物 - Google Patents

藥物化合物

Info

Publication number
HK1046133B
HK1046133B HK02107392.7A HK02107392A HK1046133B HK 1046133 B HK1046133 B HK 1046133B HK 02107392 A HK02107392 A HK 02107392A HK 1046133 B HK1046133 B HK 1046133B
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Application number
HK02107392.7A
Other languages
English (en)
Chinese (zh)
Other versions
HK1046133A1 (en
Inventor
Milton John
Vicker Nigel
John Folkes Adrian
Wang Shouming
Alexander Denny William
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of HK1046133A1 publication Critical patent/HK1046133A1/xx
Publication of HK1046133B publication Critical patent/HK1046133B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46—Phenazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK02107392.7A 1999-12-02 2002-10-10 藥物化合物 HK1046133B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9928542.1A GB9928542D0 (en) 1999-12-02 1999-12-02 Pharmaceutical compounds
PCT/GB2000/004609 WO2001046157A1 (fr) 1999-12-02 2000-12-01 Derives de benzo[a]phenazine-11-carboxamide et leur utilisation comme inhibiteurs communs de la topomerase i et ii

Publications (2)

Publication Number Publication Date
HK1046133A1 HK1046133A1 (en) 2002-12-27
HK1046133B true HK1046133B (zh) 2005-04-15

Family

ID=10865607

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107392.7A HK1046133B (zh) 1999-12-02 2002-10-10 藥物化合物

Country Status (16)

Country Link
EP (1) EP1240148A1 (fr)
JP (1) JP2003518103A (fr)
KR (1) KR100767613B1 (fr)
CN (1) CN1304380C (fr)
AU (1) AU784397B2 (fr)
BR (1) BR0016093A (fr)
CA (1) CA2392873A1 (fr)
GB (2) GB9928542D0 (fr)
HK (1) HK1046133B (fr)
HU (1) HUP0300392A3 (fr)
MX (1) MXPA02005476A (fr)
MY (1) MY136029A (fr)
PL (1) PL356482A1 (fr)
TW (1) TWI280242B (fr)
WO (1) WO2001046157A1 (fr)
ZA (1) ZA200204296B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2433071A (en) * 2005-12-05 2007-06-13 Kontrakt Technology Ltd Organic acids comprising planar conjugated heterocyclic molecular system, & photoelectric layer thereof with rodlike supramolecules for use in solar cell
CN102898388B (zh) * 2012-09-26 2014-12-03 浙江工业大学 一种合成取代苯并[α]吩嗪类化合物的方法
CN103360329B (zh) * 2013-07-18 2015-11-18 中国科学院南海海洋研究所 一类吩嗪化合物及其在制备抗肿瘤药物中的应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
CN113461623A (zh) * 2021-07-14 2021-10-01 长江大学 一种抗病毒化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE195869T1 (de) * 1992-05-28 2000-09-15 Xenova Ltd Acridin carboxamide zur behandlung von krebs
US5696131A (en) * 1993-01-22 1997-12-09 Xenova Limited Treatment of cancers
TR199900636T2 (xx) * 1996-09-23 1999-10-21 Rutgers, The State University Of New Jersey Anti-t�m�r ajanlar� olarak ikameli/katk�l� heterosayk�llar.
WO1998045272A1 (fr) * 1997-04-07 1998-10-15 Latrobe University Inhibiteurs de la topoisomerase

Also Published As

Publication number Publication date
GB2373499A (en) 2002-09-25
GB2373499B (en) 2004-11-17
KR20020070305A (ko) 2002-09-05
HUP0300392A2 (hu) 2003-07-28
BR0016093A (pt) 2002-08-20
CA2392873A1 (fr) 2001-06-28
TWI280242B (en) 2007-05-01
CN1433406A (zh) 2003-07-30
CN1304380C (zh) 2007-03-14
KR100767613B1 (ko) 2007-10-19
JP2003518103A (ja) 2003-06-03
MY136029A (en) 2008-07-31
AU1718401A (en) 2001-07-03
GB9928542D0 (en) 2000-02-02
HK1046133A1 (en) 2002-12-27
GB0215275D0 (en) 2002-08-14
EP1240148A1 (fr) 2002-09-18
ZA200204296B (en) 2003-05-29
MXPA02005476A (es) 2003-09-22
WO2001046157A1 (fr) 2001-06-28
HUP0300392A3 (en) 2003-09-29
AU784397B2 (en) 2006-03-23
PL356482A1 (en) 2004-06-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081201