HK1043791A1 - Imidazole compounds and medicinal use thereof. - Google Patents
Imidazole compounds and medicinal use thereof.Info
- Publication number
- HK1043791A1 HK1043791A1 HK02105326A HK02105326A HK1043791A1 HK 1043791 A1 HK1043791 A1 HK 1043791A1 HK 02105326 A HK02105326 A HK 02105326A HK 02105326 A HK02105326 A HK 02105326A HK 1043791 A1 HK1043791 A1 HK 1043791A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- imidazole compounds
- medicinal use
- medicinal
- imidazole
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP36736298 | 1998-12-24 | ||
JP22883899 | 1999-08-12 | ||
PCT/JP1999/007160 WO2000039097A1 (fr) | 1998-12-24 | 1999-12-20 | Composes d'imidazole et utilisation medicinale de ces composes |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1043791A1 true HK1043791A1 (en) | 2002-09-27 |
Family
ID=26528483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02105326A HK1043791A1 (en) | 1998-12-24 | 2002-07-18 | Imidazole compounds and medicinal use thereof. |
Country Status (19)
Country | Link |
---|---|
US (1) | US7060721B1 (tr) |
EP (1) | EP1142879B1 (tr) |
KR (1) | KR20010094731A (tr) |
CN (1) | CN1170822C (tr) |
AR (1) | AR022019A1 (tr) |
AT (1) | ATE375332T1 (tr) |
AU (1) | AU758325C (tr) |
BR (1) | BR9917112A (tr) |
CA (1) | CA2356838A1 (tr) |
CZ (1) | CZ20012338A3 (tr) |
DE (1) | DE69937307T2 (tr) |
ES (1) | ES2292262T3 (tr) |
HK (1) | HK1043791A1 (tr) |
HU (1) | HUP0104657A3 (tr) |
IL (1) | IL143802A0 (tr) |
RU (1) | RU2238937C2 (tr) |
TR (1) | TR200101865T2 (tr) |
TW (1) | TWI239330B (tr) |
WO (1) | WO2000039097A1 (tr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0009037D0 (en) * | 2000-04-13 | 2000-05-31 | Novartis Ag | Organic compounds |
US20030181461A1 (en) * | 2002-01-25 | 2003-09-25 | Lautt Wilfred Wayne | Use of phosphodiesterase antagonists to treat insulin resistance |
AU2012200214B2 (en) * | 2004-05-14 | 2013-10-24 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
ES2249992B1 (es) * | 2004-09-13 | 2007-03-01 | Ferrer Internacional, S.A. | Un procedimiento para fabricar compuestos enantiomericos del imidazol. |
KR20080033524A (ko) * | 2005-08-10 | 2008-04-16 | 다케다 야쿠힌 고교 가부시키가이샤 | 당뇨병 치료제 |
US20090105324A1 (en) * | 2006-04-21 | 2009-04-23 | Astrazeneca Ab | Imidazole derivatives for use as edg-1 antagonists |
TW200838501A (en) | 2007-02-02 | 2008-10-01 | Theravance Inc | Dual-acting antihypertensive agents |
MX2009008103A (es) * | 2007-02-09 | 2009-08-18 | Takeda Pharmaceutical | Compuestos anulares fusionados como agonistas parciales de prar-gamma. |
TWI448284B (zh) | 2007-04-24 | 2014-08-11 | Theravance Inc | 雙效抗高血壓劑 |
TWI406850B (zh) | 2007-06-05 | 2013-09-01 | Theravance Inc | 雙效苯并咪唑抗高血壓劑 |
KR100868898B1 (ko) * | 2007-07-30 | 2008-11-14 | 한국기계연구원 | 적층형 pzt를 이용한 압전펌프 |
US7834041B2 (en) * | 2007-09-07 | 2010-11-16 | Theravance, Inc. | Dual-acting antihypertensive agents |
JP2011506459A (ja) | 2007-12-11 | 2011-03-03 | セラヴァンス, インコーポレーテッド | 抗高血圧剤としての二重作用性ベンゾイミダゾール誘導体およびその使用 |
EP2297113A1 (en) | 2008-04-29 | 2011-03-23 | Theravance, Inc. | Dual-acting antihypertensive agents |
US8124636B2 (en) * | 2008-04-30 | 2012-02-28 | Hoffmann-La Roche Inc. | Imidazolidinone derivatives as 11B-HSD1 inhibitors |
WO2010011821A2 (en) | 2008-07-24 | 2010-01-28 | Theravance, Inc. | Dual-acting antihypertensive agents |
CA2760748A1 (en) * | 2009-05-15 | 2010-11-18 | Kai Rossen | Process for the preparation of a compound useful as an inhibitor of tafia |
JP5833000B2 (ja) | 2009-07-07 | 2015-12-16 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | 二重に作用するピラゾール抗高血圧症薬 |
WO2011011232A1 (en) | 2009-07-22 | 2011-01-27 | Theravance, Inc. | Dual-acting oxazole antihypertensive agents |
JP2013517295A (ja) | 2010-01-19 | 2013-05-16 | セラヴァンス, インコーポレーテッド | 二重に作用するチオフェン、ピロール、チアゾールおよびフラン抗高血圧症薬 |
SG11202100983XA (en) | 2018-09-04 | 2021-03-30 | Chugai Pharmaceutical Co Ltd | Method of producing tetracyclic compound |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215994A (en) | 1990-09-25 | 1993-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Angiotenin II antagonizing heterocyclic derivatives |
TW235963B (tr) | 1992-01-16 | 1994-12-11 | Shionogi & Co | |
BR9612434A (pt) | 1995-12-28 | 1999-12-28 | Fujiwasa Pharmaceutical Co Ltd | Derivados de benzimidazol |
KR20010014183A (ko) | 1997-06-27 | 2001-02-26 | Fujisawa Pharmaceutical Co | 술폰아미드 화합물 및 그의 의약 용도 |
EP1000932B9 (en) | 1997-06-27 | 2005-12-28 | Fujisawa Pharmaceutical Co., Ltd. | Aromatic ring derivatives |
-
1999
- 1999-12-20 CZ CZ20012338A patent/CZ20012338A3/cs unknown
- 1999-12-20 ES ES99959929T patent/ES2292262T3/es not_active Expired - Lifetime
- 1999-12-20 BR BR9917112-0A patent/BR9917112A/pt not_active IP Right Cessation
- 1999-12-20 HU HU0104657A patent/HUP0104657A3/hu unknown
- 1999-12-20 EP EP99959929A patent/EP1142879B1/en not_active Expired - Lifetime
- 1999-12-20 CA CA002356838A patent/CA2356838A1/en not_active Abandoned
- 1999-12-20 CN CNB998163600A patent/CN1170822C/zh not_active Expired - Fee Related
- 1999-12-20 RU RU2001120723A patent/RU2238937C2/ru not_active IP Right Cessation
- 1999-12-20 WO PCT/JP1999/007160 patent/WO2000039097A1/ja not_active Application Discontinuation
- 1999-12-20 DE DE69937307T patent/DE69937307T2/de not_active Expired - Fee Related
- 1999-12-20 AU AU16905/00A patent/AU758325C/en not_active Ceased
- 1999-12-20 US US09/869,135 patent/US7060721B1/en not_active Expired - Fee Related
- 1999-12-20 KR KR1020017008097A patent/KR20010094731A/ko not_active Application Discontinuation
- 1999-12-20 IL IL14380299A patent/IL143802A0/xx unknown
- 1999-12-20 TR TR2001/01865T patent/TR200101865T2/tr unknown
- 1999-12-20 AT AT99959929T patent/ATE375332T1/de not_active IP Right Cessation
- 1999-12-22 TW TW088122630A patent/TWI239330B/zh not_active IP Right Cessation
- 1999-12-23 AR ARP990106750A patent/AR022019A1/es unknown
-
2002
- 2002-07-18 HK HK02105326A patent/HK1043791A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL143802A0 (en) | 2002-04-21 |
BR9917112A (pt) | 2002-01-29 |
AU758325C (en) | 2004-10-07 |
AU1690500A (en) | 2000-07-31 |
CZ20012338A3 (cs) | 2001-12-12 |
CA2356838A1 (en) | 2000-07-06 |
TWI239330B (en) | 2005-09-11 |
AR022019A1 (es) | 2002-09-04 |
TR200101865T2 (tr) | 2001-12-21 |
RU2238937C2 (ru) | 2004-10-27 |
CN1335837A (zh) | 2002-02-13 |
CN1170822C (zh) | 2004-10-13 |
US7060721B1 (en) | 2006-06-13 |
DE69937307T2 (de) | 2008-02-07 |
EP1142879B1 (en) | 2007-10-10 |
WO2000039097A1 (fr) | 2000-07-06 |
HUP0104657A2 (hu) | 2002-05-29 |
DE69937307D1 (de) | 2007-11-22 |
EP1142879A4 (en) | 2002-02-06 |
KR20010094731A (ko) | 2001-11-01 |
ATE375332T1 (de) | 2007-10-15 |
EP1142879A1 (en) | 2001-10-10 |
HUP0104657A3 (en) | 2002-07-29 |
ES2292262T3 (es) | 2008-03-01 |
AU758325B2 (en) | 2003-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20081220 |