DE3770982D1
(de)
*
|
1986-04-24 |
1991-08-01 |
Fujisawa Pharmaceutical Co |
Diphosphonsaeure-verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel.
|
DE3770787D1
(en)
*
|
1986-11-21 |
1991-07-18 |
Ciba Geigy Ag |
Aromatisch substituierte azacyclo-alkylalkandiphosphonsaeuren.
|
DE3640938A1
(de)
*
|
1986-11-29 |
1988-06-01 |
Boehringer Mannheim Gmbh |
Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindung enthaltende arzneimittel
|
US5190930A
(en)
*
|
1987-12-11 |
1993-03-02 |
Ciba-Geigy Corporation |
Araliphatylaminoalkanediphosphonic acids
|
US5110807A
(en)
*
|
1988-12-01 |
1992-05-05 |
Ciba-Geigy Corporation |
Araliphatylaminoalkanediphosphonic acids
|
US7452359B1
(en)
*
|
1988-06-13 |
2008-11-18 |
Warsaw Orthopedic, Inc. |
Apparatus for inserting spinal implants
|
AU5185790A
(en)
*
|
1989-02-16 |
1990-09-05 |
University Of Georgia Research Foundation, Inc., The |
Treatment of tibial dyschondroplasia
|
US5316770A
(en)
*
|
1989-02-16 |
1994-05-31 |
University Of Georgia Research Foundation, Inc. |
Vitamin D derivative feed compositions and methods of use
|
US5366736A
(en)
*
|
1989-02-16 |
1994-11-22 |
University Of Georgia Research Foundation, Inc. |
Vitamin D derivative feed compositions and methods of use
|
MX21452A
(es)
*
|
1989-07-07 |
1994-01-31 |
Ciba Geigy Ag |
Preparaciones farmaceuticas que se administran en forma topica.
|
US5139786A
(en)
*
|
1989-07-07 |
1992-08-18 |
Ciba-Geigy Corporation |
Topical formulations
|
US5356887A
(en)
*
|
1990-01-31 |
1994-10-18 |
Merck & Co., Inc. |
Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids
|
US5204334A
(en)
*
|
1990-10-18 |
1993-04-20 |
Ciba-Geigy Corporation |
Benzoheterocyclylalkylaminoalkanediphosphonic acids, compositions thereof, and use thereof in the treatment of calcium metabolism disorders
|
ATE119777T1
(de)
|
1991-02-26 |
1995-04-15 |
Procter & Gamble Pharma |
Behandlungsmethoden für osteoporose.
|
DK0531253T3
(da)
*
|
1991-08-27 |
1997-01-27 |
Ciba Geigy Ag |
N-substituerede aminomethandiphosphonsyrer
|
WO1993011786A1
(en)
*
|
1991-12-17 |
1993-06-24 |
Procter & Gamble Pharmaceuticals, Inc. |
Methods for the treatment of osteoporosis using bisphosphonates and parathyroid hormone
|
US5382658A
(en)
*
|
1992-04-03 |
1995-01-17 |
Allelix Biopharmaceuticals Inc. |
Stability-enhanced variants of parathyroid hormone
|
JP4481368B2
(ja)
*
|
1992-06-30 |
2010-06-16 |
味の素株式会社 |
骨粗鬆症の治療用のためのホスホネート類の用途
|
US5409911A
(en)
*
|
1992-09-11 |
1995-04-25 |
Merck & Co., Inc. |
Prostaglandin analog for treating osteoporosis
|
US5366965A
(en)
*
|
1993-01-29 |
1994-11-22 |
Boehringer Mannheim Gmbh |
Regimen for treatment or prophylaxis of osteoporosis
|
US5449819A
(en)
*
|
1994-06-06 |
1995-09-12 |
Merck & Co., Inc. |
Process for removing waste pox, alendronate and its by products
|
FR2727629A1
(fr)
*
|
1994-12-06 |
1996-06-07 |
Sanofi Sa |
Trousse pour cycle de traitement de l'osteoporose
|
US20010051616A1
(en)
*
|
1995-02-17 |
2001-12-13 |
David B. Karpf |
Method of lessening the risk of vertebral fractures
|
EP0809502A4
(en)
*
|
1995-02-17 |
2001-12-05 |
Merck & Co Inc |
PROCESS FOR REDUCING THE RISK OF BONE FRACTURES OTHER THAN VERTEBRAL FRACTURES
|
EP0831756A1
(en)
|
1995-06-06 |
1998-04-01 |
Merck & Co., Inc. |
Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
|
US20010031244A1
(en)
*
|
1997-06-13 |
2001-10-18 |
Chiesi Farmaceutici S.P.A. |
Pharmaceutical aerosol composition
|
US6432932B1
(en)
|
1997-07-22 |
2002-08-13 |
Merck & Co., Inc. |
Method for inhibiting bone resorption
|
US5994329A
(en)
|
1997-07-22 |
1999-11-30 |
Merck & Co., Inc. |
Method for inhibiting bone resorption
|
IT1303672B1
(it)
*
|
1998-07-28 |
2001-02-23 |
Nicox Sa |
Sali nitrati di farmaci attivi nei disordini ossei
|
WO2000023594A1
(en)
|
1998-10-22 |
2000-04-27 |
The General Hospital Corporation |
BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP)
|
US6121253A
(en)
*
|
1998-11-20 |
2000-09-19 |
Merck Frosst Canada & Co. |
Prostaglandin conjugates for treating or preventing bone disease
|
US7057012B1
(en)
*
|
1998-12-31 |
2006-06-06 |
The General Hospital Corporation |
PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules
|
JP2002533115A
(ja)
*
|
1998-12-31 |
2002-10-08 |
ザ ジェネラル ホスピタル コーポレーション |
Pth機能的ドメイン結合体ペプチド、それらの誘導体、および新規係留リガンド−レセプター分子
|
US7534605B2
(en)
|
1999-06-08 |
2009-05-19 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
|
EP1222208B1
(en)
|
1999-09-29 |
2008-10-29 |
The General Hospital Corporation |
Polypeptide derivatives of parathyroid hormone (pth)
|
AU7734800A
(en)
*
|
1999-09-29 |
2001-04-30 |
General Hospital Corporation, The |
Polypeptide derivatives of parathyroid hormone (pth)
|
US7022815B1
(en)
|
1999-09-29 |
2006-04-04 |
The General Hospital Corporation |
Polypeptide derivatives of parathyroid hormone (PTH)
|
FR2801218B1
(fr)
*
|
1999-11-23 |
2001-12-28 |
Hoechst Marion Roussel Inc |
Compositions pharmaceutiques comprenant de la trimegestone, leurs procedes de preparation ainsi que le conditionnement primaire les renfermant
|
WO2001046040A1
(en)
|
1999-12-20 |
2001-06-28 |
Merck & Co., Inc. |
Blister package for pharmaceutical treatment card
|
US6677320B2
(en)
|
2000-01-20 |
2004-01-13 |
Hoffmann-La Roches Inc. |
Parenteral bisphosphonate composition with improved local tolerance
|
US6833357B2
(en)
*
|
2000-06-20 |
2004-12-21 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for modulating muscle cell and tissue contractility
|
NZ523086A
(en)
*
|
2000-06-20 |
2007-07-27 |
Novartis Ag |
Method of administering bisphosphonates
|
US20050147602A1
(en)
*
|
2000-10-19 |
2005-07-07 |
Maine Medical Center Research Institute |
Compositions, methods and kits relating to CTHRC1, a novel modulator of collagen matrix
|
US6630325B1
(en)
*
|
2000-10-19 |
2003-10-07 |
Maine Medical Center Research Institute |
Compositions, methods and kits relating to remodel
|
AU2002339843B2
(en)
*
|
2001-07-23 |
2007-12-06 |
The General Hospital Corporation |
Conformationally constrained parathyroid hormone (PTH) analogs
|
US20030119771A1
(en)
*
|
2001-08-22 |
2003-06-26 |
Rompaey Luc Van |
Modulators of bone homeostasis identified in a high-throughput screen
|
US20080057059A1
(en)
*
|
2001-11-09 |
2008-03-06 |
Novo Nordisk Healthcare A/G |
Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors
|
US20030124118A1
(en)
*
|
2001-11-27 |
2003-07-03 |
Rasmus Rojkjaer |
Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors
|
US20050070504A1
(en)
*
|
2001-12-21 |
2005-03-31 |
The Procter & Gamble Co. |
Risedronate compositions and their methods of use
|
WO2003055496A1
(en)
*
|
2001-12-21 |
2003-07-10 |
The Procter & Gamble Company |
Method for the treatment of bone disorders
|
CA2472578A1
(en)
*
|
2002-01-24 |
2003-07-31 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Anti-cancer combination and use thereof
|
WO2003086415A1
(en)
*
|
2002-04-05 |
2003-10-23 |
Merck & Co., Inc. |
Method for inhibiting bone resorption with an alendronate and vitamin d formulation
|
KR20120065435A
(ko)
|
2002-05-10 |
2012-06-20 |
에프. 호프만-라 로슈 아게 |
골다공증 치료 및 예방용 비스포스폰산
|
JP2005534653A
(ja)
*
|
2002-06-06 |
2005-11-17 |
メルク フロスト カナダ アンド カンパニー |
眼及び骨疾患の治療に於いてep4受容体作動薬として使用するための1,5−二置換イミダゾリジン−2−オン誘導体
|
FR2841472B1
(fr)
|
2002-06-28 |
2006-02-24 |
Agronomique Inst Nat Rech |
Composition nutritionnelle ou therapeutique contenant le compose hesperidine ou l'un de ses derives
|
US20050031610A1
(en)
*
|
2002-07-19 |
2005-02-10 |
Tae-Wan Kim |
CD44-related fragments, compositions and methods
|
US20040138180A1
(en)
*
|
2002-10-03 |
2004-07-15 |
Barr Laboratories, Inc. |
Bisphosphonate composition and process for the preparation thereof
|
BE1015150A3
(nl)
*
|
2002-10-21 |
2004-10-05 |
Sonitron Nv |
Verbeterde transducent
|
BR0309691A
(pt)
*
|
2002-12-20 |
2005-08-02 |
Hoffmann La Roche |
Formulação de ibandronato em alta dose
|
WO2004067021A1
(en)
*
|
2003-01-24 |
2004-08-12 |
Gardella Thomas J |
Conformationally constrained parathyroid hormone (pth) analogs with lactam bridges
|
US7795220B2
(en)
*
|
2003-03-19 |
2010-09-14 |
The General Hospital Corporation |
Conformationally constrained parathyroid hormones with alpha-helix stabilizers
|
FR2853549B1
(fr)
|
2003-04-11 |
2007-11-09 |
Agronomique Inst Nat Rech |
Composition nutritionnelle ou therapeutique contenant le compose oleuropeine ou l'un de ses derives
|
EP1653985A4
(en)
|
2003-07-17 |
2009-08-05 |
Gen Hospital Corp |
CONSTRAINTS CONTAINING CONTAINING HORMONE PARATHYROID (PTH) ANALOGUES
|
US20050043359A1
(en)
*
|
2003-08-20 |
2005-02-24 |
The Procter & Gamble Company |
Kit for treatment of upper gastrointestinal tract conditions
|
EP1673336B1
(en)
|
2003-08-21 |
2014-06-04 |
Merck Canada Inc. |
Cathepsin cysteine protease inhibitors
|
CA2539359A1
(en)
*
|
2003-09-19 |
2005-03-31 |
Pfizer Products Inc. |
Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a bisphosphonate
|
US20050261250A1
(en)
*
|
2004-05-19 |
2005-11-24 |
Merck & Co., Inc., |
Compositions and methods for inhibiting bone resorption
|
KR20080083068A
(ko)
|
2004-05-24 |
2008-09-12 |
더 프록터 앤드 갬블 캄파니 |
킬레이팅제를 함유하는 비스포스포네이트의 고형의 장용 경구 투여 형태
|
UA87854C2
(en)
|
2004-06-07 |
2009-08-25 |
Мерк Энд Ко., Инк. |
N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
|
EP1855674B1
(en)
|
2005-03-02 |
2014-07-16 |
Merck Sharp & Dohme Corp. |
Composition for inhibition of cathepsin k
|
BRPI0606280A2
(pt)
*
|
2005-03-17 |
2009-06-09 |
Elan Pharma Int Ltd |
composições de bisfosfonato nanoparticulado
|
EP1888037A2
(en)
*
|
2005-05-10 |
2008-02-20 |
Elan Pharma International Limited |
Nanoparticulate clopidogrel formulations
|
RU2437565C2
(ru)
*
|
2005-06-02 |
2011-12-27 |
Ю. Эс. Боракс Инк. |
Композиция кормового продукта для профилактики или лечения остеохондроза (варианты), способ профилактики или лечения остеохондроза
|
US20080293677A1
(en)
*
|
2005-06-06 |
2008-11-27 |
Brookler Kenneth H |
Use of Alternating Amine and Non-Amine Bisphosphonate Combinations For Treating Osteoporosis
|
JP2009545320A
(ja)
*
|
2006-08-04 |
2009-12-24 |
ザ ジェネラル ホスピタル コーポレイション |
副甲状腺ホルモン(pth)のポリペプチド誘導体
|
US7781418B2
(en)
|
2006-12-14 |
2010-08-24 |
Isis Innovation Ltd. |
Composition for treating bone disorders
|
AU2008282805B2
(en)
|
2007-08-01 |
2014-05-01 |
Chugai Pharmaceutical Co., Ltd. |
Screening methods using G-protein coupled receptors and related compositions
|
EP2489656A1
(en)
|
2007-12-21 |
2012-08-22 |
Ligand Pharmaceuticals Inc. |
Selective androgen receptor modulators (sarms) and uses thereof
|
US20100068211A1
(en)
*
|
2008-02-08 |
2010-03-18 |
Bateman Ted A |
Use of antiresorptive compounds to prevent ionizing radiation-induced activation of osteoclasts and resulting bone loss
|
US20120100206A1
(en)
|
2009-06-11 |
2012-04-26 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Targeted liposomes comprising n-containing bisphosphonates and uses thereof
|
US8882740B2
(en)
*
|
2009-12-23 |
2014-11-11 |
Stryker Trauma Gmbh |
Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
|
RU2604809C2
(ru)
|
2010-05-13 |
2016-12-10 |
Дзе Дженерал Хоспитал Корпорейшн |
Аналоги паратиреоидного гормона и их применение
|
CN102372773B
(zh)
*
|
2010-08-11 |
2013-06-05 |
中国科学院生物物理研究所 |
人膀胱癌肿瘤标志物及其抗体和应用
|
EP2675440B1
(en)
|
2011-02-14 |
2020-03-25 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
EP2716297B1
(en)
*
|
2011-03-11 |
2017-09-27 |
Tokyo University of Science Foundation |
D-glu-fniii14 polypeptide for use in treating cancer
|
PL2731591T3
(pl)
|
2011-07-13 |
2021-05-17 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Liposomy zawierające bisfosfonian i środek amfipatyczny w wyniku ko-enkapsulacji
|
FR3005419B1
(fr)
|
2013-05-13 |
2015-09-04 |
Agronomique Inst Nat Rech |
Utilisation d'une association de deux composes pour le traitement et/ou la prevention de troubles osseux
|
CN105593230B
(zh)
|
2013-10-08 |
2018-07-06 |
默沙东公司 |
组织蛋白酶半胱氨酸蛋白酶抑制剂
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
PL407922A1
(pl)
|
2014-04-16 |
2015-10-26 |
Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością |
Nowe bisfosfoniany i ich zastosowanie
|
KR20160147007A
(ko)
|
2014-05-30 |
2016-12-21 |
화이자 인코포레이티드 |
선택적인 안드로겐 수용체 조절제로서의 카보니트릴 유도체
|
HUE049261T2
(hu)
|
2014-07-15 |
2020-09-28 |
Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd |
CD44 izolált polipeptidek és alkalmazásaik
|
FR3066919B1
(fr)
|
2017-06-06 |
2019-08-02 |
Institut National De La Recherche Agronomique (Inra) |
Composition de phycocyanine pour son utilisation pour inhiber la resorption osseuse.
|
WO2023275715A1
(en)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Metabolites of selective androgen receptor modulators
|