HK1035488A1 - Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof - Google Patents

Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof

Info

Publication number
HK1035488A1
HK1035488A1 HK01106008A HK01106008A HK1035488A1 HK 1035488 A1 HK1035488 A1 HK 1035488A1 HK 01106008 A HK01106008 A HK 01106008A HK 01106008 A HK01106008 A HK 01106008A HK 1035488 A1 HK1035488 A1 HK 1035488A1
Authority
HK
Hong Kong
Prior art keywords
fraction
mmp
preparation
kda
extracts
Prior art date
Application number
HK01106008A
Other languages
English (en)
Inventor
Eric Dupont
Yves Lachance
Denis Lessard
Serge Auger
Original Assignee
Aeterna Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Lab Inc filed Critical Aeterna Lab Inc
Publication of HK1035488A1 publication Critical patent/HK1035488A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK01106008A 1998-07-23 2001-08-27 Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof HK1035488A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/122,481 US6168807B1 (en) 1998-07-23 1998-07-23 Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
PCT/CA1999/000674 WO2000004910A2 (en) 1998-07-23 1999-07-23 Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
HK1035488A1 true HK1035488A1 (en) 2001-11-30

Family

ID=22402955

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01106008A HK1035488A1 (en) 1998-07-23 2001-08-27 Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof

Country Status (11)

Country Link
US (2) US6168807B1 (xx)
EP (1) EP1098656B1 (xx)
JP (1) JP2002521340A (xx)
CN (1) CN1314816A (xx)
AT (1) ATE250422T1 (xx)
AU (1) AU4893199A (xx)
CA (1) CA2338068A1 (xx)
DE (1) DE69911614T2 (xx)
ES (1) ES2207248T3 (xx)
HK (1) HK1035488A1 (xx)
WO (1) WO2000004910A2 (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6380366B1 (en) 1994-04-28 2002-04-30 Les Laboratoires Aeterna Inc. Shark cartilage extract:process of making, methods of using and compositions thereof
RU2195946C2 (ru) 1997-03-11 2003-01-10 Ле Лабораториз Аетерна Инк. Противоопухолевые терапевтические средства, включающие комбинацию экстракта хряща и антинеопластического агента, обеспечивающие высокую эффективность действия при низких токсических побочных эффектах
US20020009501A1 (en) * 1998-07-23 2002-01-24 Eric Dupont Preparation of cartilage extracts using organic solvents
US6168807B1 (en) 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
US20040009233A1 (en) * 2000-12-20 2004-01-15 Davis Paul Frank Shark meat extract
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
WO2003068249A1 (en) * 2002-02-15 2003-08-21 Ocean Nutrition Canada Limited Shark cartilage extracts and use thereof for immunomodulation
WO2004060425A2 (en) * 2002-12-27 2004-07-22 Angiotech International Ag Compositions and methods of using collagen and mmpi
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
EP1614697A4 (en) * 2003-03-20 2007-10-10 Hosokawa Micron Kk FROM CORTAR FISH ISOLATED PROTEOGLYKAN AND METHOD OF MANUFACTURING THEREOF
WO2006059236A2 (en) * 2004-11-16 2006-06-08 Aeterna Zentaris Inc. Method of using cartilage extract for increasing blood parameters
US20080014190A1 (en) * 2005-10-03 2008-01-17 Yong Qian Proteinases destroy cancer tumor's solid structure and kill cancer cells locally
US9072735B2 (en) 2005-10-03 2015-07-07 Yong Qian Proteinases destroy cancer tumor's solid structure and kill cancer cells locally
EP2323736A1 (en) * 2008-09-09 2011-05-25 University of East Anglia Treatment of fibrotic eye disorders using an mmp2 inhibitor
KR101539700B1 (ko) * 2012-09-05 2015-07-28 아주대학교산학협력단 연골세포 유래 세포외 기질막을 이용한 신생혈관질환 치료용 조성물 및 각막 또는 결막 이식재
CN104894200B (zh) * 2015-05-12 2020-10-30 浙江海洋学院 路氏双髻鲨软骨血管生成抑制因子的制备方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE28093E (en) 1962-02-28 1974-07-30 Wound-healing cartilage powder
US3478146A (en) 1965-02-26 1969-11-11 Leslie L Balassa Wound-healing cartilage powder extracting process
US3966908A (en) 1973-11-29 1976-06-29 Lescarden Ltd. Method of treating degenerative joint afflictions
US4042457A (en) 1975-11-10 1977-08-16 Rush-Presbyterian-St. Luke's Medical Center Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor
US4212857A (en) 1976-10-29 1980-07-15 Lescarden Ltd. Method for stimulating the production of immunoglobulin and total complement
US4822607A (en) 1976-10-29 1989-04-18 Lescarden Ltd. Anti-tumor agent and method
US4243582A (en) 1979-04-26 1981-01-06 Monsanto Company Novel glycoproteins from bovine cartilage
US4350682A (en) 1979-05-11 1982-09-21 Lescarden Ltd. Cartilage extraction processes and products
US4356261A (en) 1980-04-22 1982-10-26 Rush-Presbyterian-St. Luke's Medical Center Anti-invasion factor containing cultures
US4456589A (en) 1982-07-08 1984-06-26 Genetic Laboratories, Inc. Preparation of animal tissues for surgical implantation in human recipients
US4473551A (en) 1982-08-23 1984-09-25 Faxon Pharmaceuticals, Inc. Anti-inflammatory composition
JPS5939828A (ja) 1982-08-28 1984-03-05 Ajinomoto Co Inc 抗腫瘍活性物質の製造方法
US4444752A (en) 1982-09-13 1984-04-24 Lescarden Ltd. Method for treating progressive systemic sclerosis
US4469676A (en) 1983-06-21 1984-09-04 Michel Hecmati Method for eliminating wrinkles occurring in the human skin
JPS60178820A (ja) 1984-02-22 1985-09-12 Ajinomoto Co Inc 抗腫瘍活性物質の製造方法
US4656137A (en) 1985-09-12 1987-04-07 Lescarden Inc Method of processing animal cartilage
US4749522A (en) 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
US4746729A (en) 1986-07-30 1988-05-24 Kuettner Klaus E Cartilage-derived leukocyte elastase-inhibitor
US5075112A (en) 1990-02-12 1991-12-24 Cartilage Technologies Inc. Method of and dosage unit for inhibiting angiogenesis or vascularization in an animal using shark cartilage
US5260205A (en) * 1990-11-14 1993-11-09 Philip Morris Incorporated Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine
WO1993009766A1 (en) 1991-11-15 1993-05-27 Arthro Research And Development Corporation Method for treatment of acute and chronic painful arthropathic conditions in human and other mammals
WO1994012510A1 (en) 1992-11-30 1994-06-09 Lane I William Processing shark cartilage
DE69435342D1 (de) 1993-07-19 2011-05-05 Angiotech Pharm Inc Anti-Angiogene Mittel und Verfahren zu deren Verwendung
US6025334A (en) 1994-04-28 2000-02-15 Les Laboratoires Aeterna Inc. Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof
US6028118A (en) 1996-08-08 2000-02-22 Les Laboratoires Aeterna Inc. Methods of using extracts of shark cartilage
US5618925A (en) 1994-04-28 1997-04-08 Les Laboratories Aeterna Inc. Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
CZ292627B6 (cs) 1995-02-03 2003-11-12 Les Laboratoires Aeterna Inc. Léčivo pro léčení nemocí nebo poruch majících složku kolagenolytickou nebo zánětlivou
US5843920A (en) * 1996-09-16 1998-12-01 Biocell Technology, Llc Anionic saccharides for extraction of anti-angiogenic protein from cartilage
US6168807B1 (en) 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof

Also Published As

Publication number Publication date
AU4893199A (en) 2000-02-14
WO2000004910A2 (en) 2000-02-03
WO2000004910A3 (en) 2000-05-04
US6168807B1 (en) 2001-01-02
US20010001041A1 (en) 2001-05-10
DE69911614T2 (de) 2004-06-03
CA2338068A1 (en) 2000-02-03
ATE250422T1 (de) 2003-10-15
US6506414B2 (en) 2003-01-14
DE69911614D1 (de) 2003-10-30
CN1314816A (zh) 2001-09-26
EP1098656A2 (en) 2001-05-16
ES2207248T3 (es) 2004-05-16
EP1098656B1 (en) 2003-09-24
JP2002521340A (ja) 2002-07-16

Similar Documents

Publication Publication Date Title
HK1035488A1 (en) Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
ZA942967B (en) Rigid-rod polymer based on pyridobisimidazole.
DE69324006D1 (de) Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung
BR9407910A (pt) Composto composiçao farmacêutica uso do composto processo de tratamento de distúrbios no sistema nervoso central e processo de preparaçao do composto
DE60135024D1 (de) Körperreinigungsmittel
ATE196089T1 (de) Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen
ATE247666T1 (de) Wasserlöslische prodrugs von 2,6- diisopropylphenol-analoga
ATE245416T1 (de) Neue fettanaloge zur behandlung von diabetes
MD1838F2 (en) 5,6-dichlorbenzimidazole derivatives, process for obtaining thereof, pharmaceutical composition and method of treatment or prevention of herpetic viral infections
WO1987004426A3 (fr) Compositions de vinyle
EP0896533A4 (en) PENTAFLUOROBENZEN SULPHONAMIDES AND ANALOGS
SE9804000D0 (sv) New composition of matter
ATE292976T1 (de) Verwendung von angiotensin analogen zur herstellung eines arzneimittels zur steigerung des ueberlebens der weissen blutzellen und mobilisierung von haematopoietischen stammzellen nach einer chemotherapeutischen behandlung
GB2334446A (en) Aqueous compositions compromising a lipid and a lanolin-derived surfactant,and their use
NO954957D0 (no) Synergistisk stabiliserte flytende enzymatiske blandinger
UA66861C2 (uk) 2-феніл-1-[4-(2-аміноетокси)бензил]індол в комбінації з естрогенами, способи лікування та продукт для лікування
AU2101800A (en) Skin protection agents containing a fragment mixture produced from hyaluronic acid by hydrolysis
FR2861731B1 (fr) Nouvelle proteine de fixation du phosphate, compositions pharmaceutiques la contenant et ses utilisations
WO2004000045A3 (en) Liquid compositions comprising non-digestible oligosaccharides and green tea catechins, method and uses thereof
AU6415994A (en) Substituted caprolactams and derivatives thereof useful for treatment of hiv disease
WO2002005801A3 (en) Compositions containing diacyltartaric salts of (e)-metanicotine
TNSN99083A1 (fr) Derives d'hygromycine a et leur procede de preparation.
FR2800073B1 (fr) Nouveaux composes silicies derives de l'acide ascorbique, procede de preparation, compositions les comprenant et utilisations
FR2768145B1 (fr) Nouveaux composes derives d'acide alkylene diamine di- ou tri-acetique, leur procede de preparation, leur utilisation dans des compositions cosmetiques et pharmaceutiques, et compositions les comprenant
EP0393636A3 (en) Liquid crystal composition and liquid crystal display using said composition

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070723