HK1030937A1 - New substituted dimeric compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents
New substituted dimeric compounds, a process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HK1030937A1 HK1030937A1 HK01101746A HK01101746A HK1030937A1 HK 1030937 A1 HK1030937 A1 HK 1030937A1 HK 01101746 A HK01101746 A HK 01101746A HK 01101746 A HK01101746 A HK 01101746A HK 1030937 A1 HK1030937 A1 HK 1030937A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nr1c
- nr2r3
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9906331A FR2793793B1 (fr) | 1999-05-19 | 1999-05-19 | Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1030937A1 true HK1030937A1 (en) | 2001-05-25 |
Family
ID=9545746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK01101746A HK1030937A1 (en) | 1999-05-19 | 2001-03-12 | New substituted dimeric compounds, a process for their preparation and pharmaceutical compositions containing them |
Country Status (21)
Country | Link |
---|---|
US (1) | US6310074B1 (hu) |
EP (1) | EP1057826B1 (hu) |
JP (1) | JP3688552B2 (hu) |
KR (1) | KR100472520B1 (hu) |
CN (1) | CN1128142C (hu) |
AT (1) | ATE237610T1 (hu) |
AU (1) | AU766322B2 (hu) |
BR (1) | BR0003313A (hu) |
DE (1) | DE60002126T2 (hu) |
DK (1) | DK1057826T3 (hu) |
EA (1) | EA003391B1 (hu) |
ES (1) | ES2197062T3 (hu) |
FR (1) | FR2793793B1 (hu) |
HK (1) | HK1030937A1 (hu) |
HU (1) | HUP0001961A3 (hu) |
NO (1) | NO20002548L (hu) |
NZ (1) | NZ504613A (hu) |
PL (1) | PL340165A1 (hu) |
PT (1) | PT1057826E (hu) |
SI (1) | SI1057826T1 (hu) |
ZA (1) | ZA200002490B (hu) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1713908B (zh) * | 2002-12-03 | 2010-05-12 | 弗·哈夫曼-拉罗切有限公司 | 作为5-ht6-受体配体用于治疗中枢神经系统病症的氨基烷氧基吲哚 |
DK1696920T3 (en) | 2003-12-19 | 2015-01-19 | Plexxikon Inc | RELATIONS AND PROCEDURES FOR THE DEVELOPMENT OF LAW MODULATORS |
US7498342B2 (en) * | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
JP2008545652A (ja) * | 2005-05-17 | 2008-12-18 | プレキシコン,インコーポレーテッド | c−kitおよびc−fms活性を調節する化合物およびその用途 |
MY153898A (en) * | 2005-06-22 | 2015-04-15 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
PE20081581A1 (es) * | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
WO2008079909A1 (en) * | 2006-12-21 | 2008-07-03 | Plexxikon, Inc. | Pyrrolo [2,3-b] pyridines as kinase modulators |
RU2009122670A (ru) | 2006-12-21 | 2011-01-27 | Плекссикон, Инк. (Us) | Соединения и способы для модуляции киназ и показания к их применению |
MX2010000617A (es) | 2007-07-17 | 2010-05-17 | Plexxikon Inc | Compuestos y metodos para modulacion de cinasa, e indicaciones de estos. |
CN102112480A (zh) * | 2008-07-30 | 2011-06-29 | 菲尔若国际公司 | 1,6-二氢-2h-3-氧杂-6-氮杂-不对称引达省化合物 |
NZ594398A (en) | 2009-04-03 | 2014-03-28 | Plexxikon Inc | Propane-1-sulfonic acid (3-[5-(4-chloro-phenyl)-1h-pyrrol [2, 3-b] pyridine-3-carbonyl]-2,4-difluoro-phenyl} -amide compositions and uses thereof |
US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
KR20120102669A (ko) | 2009-11-06 | 2012-09-18 | 플렉시콘, 인코퍼레이티드 | 키나제 조정을 위한 화합물 및 방법, 및 이를 위한 적응증 |
US9624213B2 (en) | 2011-02-07 | 2017-04-18 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1639427A3 (ru) * | 1987-07-03 | 1991-03-30 | Глэксо Груп Лимитед (Фирма) | Способ получени производных индола или их фармацевтически приемлемых солей |
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
ATE138374T1 (de) * | 1991-11-18 | 1996-06-15 | Lilly Industries Ltd | Benzo(b)thiophen-2-carboxamide zur behandlung von krankheiten des zentralnervensystems |
FR2689124A1 (fr) * | 1992-03-27 | 1993-10-01 | Adir | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
FR2696453B1 (fr) * | 1992-10-02 | 1994-12-23 | Adir | Nouveaux arylalkyl(thio)amides, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent. |
WO1994014769A1 (en) * | 1992-12-21 | 1994-07-07 | Taisho Pharmaceutical Co., Ltd. | N-substituted indole derivative |
PT767782E (pt) * | 1994-06-29 | 2002-03-28 | Pfizer | Derivados arilo e heteroarilo de alcoxinaftalenos |
FR2731223A1 (fr) * | 1995-03-02 | 1996-09-06 | Pf Medicament | Nouveaux derives bi-tryptaminiques, leur procede de preparation et leur utilisation a titre de medicaments |
-
1999
- 1999-05-19 FR FR9906331A patent/FR2793793B1/fr not_active Expired - Fee Related
-
2000
- 2000-05-18 NZ NZ504613A patent/NZ504613A/en unknown
- 2000-05-18 US US09/573,704 patent/US6310074B1/en not_active Expired - Fee Related
- 2000-05-18 HU HU0001961A patent/HUP0001961A3/hu unknown
- 2000-05-18 EA EA200000431A patent/EA003391B1/ru not_active IP Right Cessation
- 2000-05-18 PL PL00340165A patent/PL340165A1/xx not_active Application Discontinuation
- 2000-05-18 NO NO20002548A patent/NO20002548L/no not_active Application Discontinuation
- 2000-05-19 AU AU35420/00A patent/AU766322B2/en not_active Ceased
- 2000-05-19 KR KR10-2000-0026963A patent/KR100472520B1/ko not_active IP Right Cessation
- 2000-05-19 BR BR0003313-8A patent/BR0003313A/pt not_active Application Discontinuation
- 2000-05-19 JP JP2000147379A patent/JP3688552B2/ja not_active Expired - Fee Related
- 2000-05-19 CN CN00120095A patent/CN1128142C/zh not_active Expired - Fee Related
- 2000-05-19 ZA ZA200002490A patent/ZA200002490B/xx unknown
- 2000-05-22 DK DK00610050T patent/DK1057826T3/da active
- 2000-05-22 AT AT00610050T patent/ATE237610T1/de not_active IP Right Cessation
- 2000-05-22 DE DE60002126T patent/DE60002126T2/de not_active Expired - Fee Related
- 2000-05-22 PT PT00610050T patent/PT1057826E/pt unknown
- 2000-05-22 EP EP00610050A patent/EP1057826B1/fr not_active Expired - Lifetime
- 2000-05-22 ES ES00610050T patent/ES2197062T3/es not_active Expired - Lifetime
- 2000-05-22 SI SI200030081T patent/SI1057826T1/xx unknown
-
2001
- 2001-03-12 HK HK01101746A patent/HK1030937A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1057826A1 (fr) | 2000-12-06 |
NZ504613A (en) | 2001-06-29 |
US6310074B1 (en) | 2001-10-30 |
DE60002126T2 (de) | 2004-03-18 |
BR0003313A (pt) | 2001-03-13 |
PT1057826E (pt) | 2003-08-29 |
CN1128142C (zh) | 2003-11-19 |
EA200000431A3 (ru) | 2001-02-26 |
KR20010029729A (ko) | 2001-04-16 |
HU0001961D0 (en) | 2000-07-28 |
JP2001011035A (ja) | 2001-01-16 |
HUP0001961A3 (en) | 2002-10-28 |
PL340165A1 (en) | 2000-11-20 |
NO20002548L (no) | 2000-11-20 |
CN1277962A (zh) | 2000-12-27 |
DK1057826T3 (da) | 2003-07-21 |
ES2197062T3 (es) | 2004-01-01 |
SI1057826T1 (en) | 2003-08-31 |
FR2793793A1 (fr) | 2000-11-24 |
HUP0001961A2 (hu) | 2001-08-28 |
EA200000431A2 (ru) | 2000-12-25 |
FR2793793B1 (fr) | 2004-02-27 |
DE60002126D1 (de) | 2003-05-22 |
NO20002548D0 (no) | 2000-05-18 |
ZA200002490B (en) | 2000-11-20 |
AU766322B2 (en) | 2003-10-16 |
EA003391B1 (ru) | 2003-04-24 |
EP1057826B1 (fr) | 2003-04-16 |
KR100472520B1 (ko) | 2005-03-07 |
ATE237610T1 (de) | 2003-05-15 |
JP3688552B2 (ja) | 2005-08-31 |
AU3542000A (en) | 2000-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20090519 |