HK1029921A1 - Stabilized composition of tetrahydropyrrolo Ä1,2-aÜpyrazine-4-spiro-3'-pyrrolidine. - Google Patents

Stabilized composition of tetrahydropyrrolo Ä1,2-aÜpyrazine-4-spiro-3'-pyrrolidine.

Info

Publication number
HK1029921A1
HK1029921A1 HK01100616A HK01100616A HK1029921A1 HK 1029921 A1 HK1029921 A1 HK 1029921A1 HK 01100616 A HK01100616 A HK 01100616A HK 01100616 A HK01100616 A HK 01100616A HK 1029921 A1 HK1029921 A1 HK 1029921A1
Authority
HK
Hong Kong
Prior art keywords
acid
tetrahydropyrrolo
spiro
pyrrolidine
aüpyrazine
Prior art date
Application number
HK01100616A
Other languages
English (en)
Inventor
Mamoru Ohashi
Kazuyoshi Ogasawara
Yoshimi Shirai
Hiroshi Fujioka
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of HK1029921A1 publication Critical patent/HK1029921A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/499—Spiro-condensed pyrazines or piperazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK01100616A 1997-10-20 2001-01-29 Stabilized composition of tetrahydropyrrolo Ä1,2-aÜpyrazine-4-spiro-3'-pyrrolidine. HK1029921A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30663497 1997-10-20
PCT/JP1998/004657 WO1999020276A1 (fr) 1997-10-20 1998-10-15 Composition medicamenteuse stable

Publications (1)

Publication Number Publication Date
HK1029921A1 true HK1029921A1 (en) 2001-04-20

Family

ID=17959466

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01100616A HK1029921A1 (en) 1997-10-20 2001-01-29 Stabilized composition of tetrahydropyrrolo Ä1,2-aÜpyrazine-4-spiro-3'-pyrrolidine.

Country Status (13)

Country Link
US (1) US6297244B1 (ko)
EP (1) EP1038525B1 (ko)
JP (1) JP3995414B2 (ko)
KR (1) KR100571613B1 (ko)
CN (1) CN1152686C (ko)
AT (1) ATE270552T1 (ko)
AU (1) AU9461898A (ko)
DE (1) DE69824971T2 (ko)
DK (1) DK1038525T3 (ko)
ES (1) ES2224436T3 (ko)
HK (1) HK1029921A1 (ko)
PT (1) PT1038525E (ko)
WO (1) WO1999020276A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69830333T2 (de) * 1997-10-20 2006-01-26 Dainippon Pharmaceutical Co., Ltd. SCHNELLÖSLICHE ARZNEIMITTELZUSAMMENSETZUNG ENTHALTEND MIKRONISiERTE AS-3201
AR034985A1 (es) 2001-08-08 2004-03-24 Takeda Chemical Industries Ltd Compuesto biciclico; produccion y uso del mismo
ZA200409537B (en) * 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
AU2003236156A1 (en) * 2003-04-24 2005-01-04 Shin-Jen Shiao Pharmaceutical compositions used for immune disease treatment and improvement
US20070111964A1 (en) * 2005-08-17 2007-05-17 Fleming And Company, Pharmaceuticals Vitamin B12 nasal spray and method of use
KR20110044780A (ko) * 2008-08-14 2011-04-29 교린 세이야꾸 가부시키 가이샤 안정화된 의약 조성물
KR20160013068A (ko) * 2013-05-15 2016-02-03 토비라 쎄라퓨틱스, 인크. 세니크리비록 조성물 및 이들을 만들고 이용하는 방법
US10034880B2 (en) 2014-09-11 2018-07-31 Sumitomo Dainippon Pharma Co., Ltd. Ophthalmic suspension formulation
EP3427724A4 (en) 2016-03-10 2019-11-13 Sumitomo Dainippon Pharma Co., Ltd. COMPOSITION CONTAINING FINE PARTICLES, AND PRODUCTION METHOD THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202450B (ko) * 1991-06-26 1993-03-21 Dainippon Pharmaceutical Co
JP3158128B2 (ja) * 1992-12-25 2001-04-23 大日本製薬株式会社 コハク酸イミド誘導体
JPH08176105A (ja) * 1994-12-27 1996-07-09 Dainippon Pharmaceut Co Ltd ２−カルボキシコハク酸イミド誘導体

Also Published As

Publication number Publication date
ES2224436T3 (es) 2005-03-01
JP3995414B2 (ja) 2007-10-24
KR100571613B1 (ko) 2006-04-17
KR20010015780A (ko) 2001-02-26
PT1038525E (pt) 2004-11-30
DK1038525T3 (da) 2004-08-02
AU9461898A (en) 1999-05-10
CN1152686C (zh) 2004-06-09
EP1038525A1 (en) 2000-09-27
EP1038525A4 (en) 2003-03-26
ATE270552T1 (de) 2004-07-15
US6297244B1 (en) 2001-10-02
DE69824971T2 (de) 2004-12-23
DE69824971D1 (de) 2004-08-12
WO1999020276A1 (fr) 1999-04-29
CN1282247A (zh) 2001-01-31
EP1038525B1 (en) 2004-07-07

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20141015