HK1029584A1 - New cyano-indole serotonin-reuptake inhibitor compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents
New cyano-indole serotonin-reuptake inhibitor compounds, a process for their preparation and pharmaceutical compositions containing them.Info
- Publication number
- HK1029584A1 HK1029584A1 HK01100310A HK01100310A HK1029584A1 HK 1029584 A1 HK1029584 A1 HK 1029584A1 HK 01100310 A HK01100310 A HK 01100310A HK 01100310 A HK01100310 A HK 01100310A HK 1029584 A1 HK1029584 A1 HK 1029584A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alkyl
- preparation
- pharmaceutical compositions
- cycloalkyl
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9900801A FR2788772B1 (fr) | 1999-01-26 | 1999-01-26 | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1029584A1 true HK1029584A1 (en) | 2001-04-06 |
Family
ID=9541208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK01100310A HK1029584A1 (en) | 1999-01-26 | 2001-01-12 | New cyano-indole serotonin-reuptake inhibitor compounds, a process for their preparation and pharmaceutical compositions containing them. |
Country Status (22)
Country | Link |
---|---|
US (1) | US6239129B1 (es) |
EP (1) | EP1023898B1 (es) |
JP (1) | JP2000212162A (es) |
KR (1) | KR100445389B1 (es) |
CN (1) | CN1155570C (es) |
AT (1) | ATE234093T1 (es) |
AU (1) | AU761084B2 (es) |
BR (1) | BR0000158A (es) |
CA (1) | CA2297279C (es) |
DE (1) | DE60001591T2 (es) |
DK (1) | DK1023898T3 (es) |
EA (1) | EA003146B1 (es) |
ES (1) | ES2193923T3 (es) |
FR (1) | FR2788772B1 (es) |
HK (1) | HK1029584A1 (es) |
HU (1) | HUP0000308A2 (es) |
MX (1) | MXPA00000856A (es) |
NO (1) | NO314801B1 (es) |
NZ (1) | NZ502494A (es) |
PL (1) | PL338027A1 (es) |
SI (1) | SI1023898T1 (es) |
ZA (1) | ZA200000336B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001247562A (ja) * | 2000-03-07 | 2001-09-11 | Daicel Chem Ind Ltd | アミド化合物及びその製造方法 |
SE0004245D0 (sv) | 2000-11-20 | 2000-11-20 | Pharmacia Ab | Novel compounds and their use |
AU2426602A (en) * | 2000-11-20 | 2002-05-27 | Biovitrum Ab | Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5ht-2 receptor |
HUP0400343A2 (hu) * | 2001-03-29 | 2004-09-28 | Bristol-Myers Squibb Co. | Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
RU2327685C2 (ru) * | 2002-09-17 | 2008-06-27 | Ф.Хоффманн-Ля Рош Аг | 2,7-замещенные индолы и фармацевтическая композиция, проявляющая антагонистическую активность по отношению к 5-гт6 рецептору |
US7129264B2 (en) * | 2003-04-16 | 2006-10-31 | Bristol-Myers Squibb Company | Biarylmethyl indolines and indoles as antithromboembolic agents |
EP1689389A4 (en) * | 2003-12-04 | 2009-06-17 | Nat Health Research Institutes | Indole compounds |
FR2884251B1 (fr) * | 2005-04-08 | 2007-07-13 | Servier Lab | Derives de piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK181190D0 (da) * | 1990-07-30 | 1990-07-30 | Lundbeck & Co As H | 3-aryl-indol- eller 3-aryl-indazolderivater |
TW270114B (es) * | 1993-10-22 | 1996-02-11 | Hoffmann La Roche | |
DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
US5912256A (en) * | 1996-06-20 | 1999-06-15 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
AU5343298A (en) * | 1997-01-13 | 1998-08-03 | Yamanouchi Pharmaceutical Co., Ltd. | 5-ht2c receptor agonists and aminoalkylindazole derivatives |
-
1999
- 1999-01-26 FR FR9900801A patent/FR2788772B1/fr not_active Expired - Fee Related
-
2000
- 2000-01-24 CA CA002297279A patent/CA2297279C/fr not_active Expired - Fee Related
- 2000-01-24 JP JP14544A patent/JP2000212162A/ja active Pending
- 2000-01-25 KR KR10-2000-0003388A patent/KR100445389B1/ko not_active IP Right Cessation
- 2000-01-25 EA EA200000068A patent/EA003146B1/ru not_active IP Right Cessation
- 2000-01-25 MX MXPA00000856A patent/MXPA00000856A/es not_active IP Right Cessation
- 2000-01-25 PL PL00338027A patent/PL338027A1/xx not_active Application Discontinuation
- 2000-01-25 US US09/490,909 patent/US6239129B1/en not_active Expired - Fee Related
- 2000-01-25 BR BR0000158-9A patent/BR0000158A/pt not_active Withdrawn
- 2000-01-25 NO NO20000373A patent/NO314801B1/no unknown
- 2000-01-25 AU AU13553/00A patent/AU761084B2/en not_active Ceased
- 2000-01-25 NZ NZ502494A patent/NZ502494A/en unknown
- 2000-01-26 AT AT00400193T patent/ATE234093T1/de not_active IP Right Cessation
- 2000-01-26 DE DE60001591T patent/DE60001591T2/de not_active Expired - Fee Related
- 2000-01-26 CN CNB001011561A patent/CN1155570C/zh not_active Expired - Fee Related
- 2000-01-26 EP EP00400193A patent/EP1023898B1/fr not_active Expired - Lifetime
- 2000-01-26 DK DK00400193T patent/DK1023898T3/da active
- 2000-01-26 HU HU0000308A patent/HUP0000308A2/hu unknown
- 2000-01-26 ZA ZA200000336A patent/ZA200000336B/xx unknown
- 2000-01-26 ES ES00400193T patent/ES2193923T3/es not_active Expired - Lifetime
- 2000-01-26 SI SI200030063T patent/SI1023898T1/xx unknown
-
2001
- 2001-01-12 HK HK01100310A patent/HK1029584A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU761084B2 (en) | 2003-05-29 |
JP2000212162A (ja) | 2000-08-02 |
HUP0000308A2 (en) | 2002-06-29 |
DK1023898T3 (da) | 2003-06-10 |
FR2788772A1 (fr) | 2000-07-28 |
ES2193923T3 (es) | 2003-11-16 |
DE60001591D1 (de) | 2003-04-17 |
KR20010006587A (ko) | 2001-01-26 |
NO20000373L (no) | 2000-07-27 |
DE60001591T2 (de) | 2003-12-24 |
NO20000373D0 (no) | 2000-01-25 |
BR0000158A (pt) | 2000-09-19 |
EA003146B1 (ru) | 2003-02-27 |
ZA200000336B (en) | 2000-08-15 |
EP1023898A1 (fr) | 2000-08-02 |
EA200000068A2 (ru) | 2000-08-28 |
US6239129B1 (en) | 2001-05-29 |
SI1023898T1 (en) | 2003-06-30 |
HU0000308D0 (en) | 2000-03-28 |
FR2788772B1 (fr) | 2001-03-02 |
CN1266057A (zh) | 2000-09-13 |
ATE234093T1 (de) | 2003-03-15 |
NO314801B1 (no) | 2003-05-26 |
PL338027A1 (en) | 2000-07-31 |
NZ502494A (en) | 2001-06-29 |
CA2297279A1 (fr) | 2000-07-26 |
CN1155570C (zh) | 2004-06-30 |
KR100445389B1 (ko) | 2004-08-25 |
MXPA00000856A (es) | 2002-03-08 |
CA2297279C (fr) | 2004-05-18 |
EA200000068A3 (ru) | 2000-10-30 |
EP1023898B1 (fr) | 2003-03-12 |
AU1355300A (en) | 2000-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20080126 |