HK1024695A1 - Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing them - Google Patents
Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing themInfo
- Publication number
- HK1024695A1 HK1024695A1 HK00104036A HK00104036A HK1024695A1 HK 1024695 A1 HK1024695 A1 HK 1024695A1 HK 00104036 A HK00104036 A HK 00104036A HK 00104036 A HK00104036 A HK 00104036A HK 1024695 A1 HK1024695 A1 HK 1024695A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- camptothecin
- counterparts
- medicine
- novel
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9615774A FR2757514B1 (fr) | 1996-12-20 | 1996-12-20 | Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant |
PCT/FR1997/002218 WO1998028305A1 (fr) | 1996-12-20 | 1997-12-05 | Nouveaux analogues de la camptothecine, leur application comme medicaments et les compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1024695A1 true HK1024695A1 (en) | 2000-10-20 |
Family
ID=9498938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK00104036A HK1024695A1 (en) | 1996-12-20 | 2000-07-04 | Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing them |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0946567B1 (de) |
JP (2) | JP3576175B2 (de) |
KR (1) | KR100516874B1 (de) |
CN (1) | CN1097056C (de) |
AR (1) | AR008543A1 (de) |
AT (1) | ATE248177T1 (de) |
AU (1) | AU734485B2 (de) |
BR (1) | BR9714170A (de) |
CA (1) | CA2275351C (de) |
CZ (1) | CZ299795B6 (de) |
DE (1) | DE69724453T2 (de) |
DK (1) | DK0946567T3 (de) |
ES (1) | ES2206761T3 (de) |
FR (1) | FR2757514B1 (de) |
HK (1) | HK1024695A1 (de) |
HU (1) | HUP9904210A3 (de) |
MX (1) | MXPA99005776A (de) |
MY (1) | MY119473A (de) |
NO (1) | NO326464B1 (de) |
NZ (1) | NZ335939A (de) |
PL (1) | PL188181B1 (de) |
PT (1) | PT946567E (de) |
RU (1) | RU2194051C2 (de) |
UA (1) | UA57758C2 (de) |
WO (1) | WO1998028305A1 (de) |
ZA (1) | ZA9711129B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790261B1 (fr) | 1999-02-26 | 2004-09-10 | Sod Conseils Rech Applic | Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation |
US6291676B1 (en) * | 1999-03-03 | 2001-09-18 | University Of Kentucky Research Foundation | Water-soluble derivatives of camptothecin/homocamptothecin |
US6207832B1 (en) | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
AU3455100A (en) * | 1999-05-28 | 2000-12-18 | Nippon Chemiphar Co. Ltd. | Process for the preparation of 2-halo-3-(3-quinolyl)propionic acid derivatives |
US6372906B1 (en) | 2001-04-12 | 2002-04-16 | University Of Pittsburgh | Synthesis of silyl camptothecins and silyl homocamptothecins |
US6723853B2 (en) | 2001-08-27 | 2004-04-20 | University Of Pittsburgh | Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins |
WO2003074524A2 (en) * | 2002-03-01 | 2003-09-12 | University Of Pittsburgh | Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs |
ITRM20040288A1 (it) * | 2004-06-11 | 2004-09-11 | Sigma Tau Ind Farmaceuti | Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero. |
WO2006033011A1 (en) * | 2004-09-21 | 2006-03-30 | Societe De Conseils De Recherches Et D'applications Scientifique (S.C.R.A.S.) | Novel processes for the production of useful intermediates |
CN102746314B (zh) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
WO2023232145A1 (zh) * | 2022-06-02 | 2023-12-07 | 华东师范大学 | 一种高喜树碱类小分子及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5391745A (en) * | 1992-07-23 | 1995-02-21 | Sloan-Kettering Institute For Cancer Research | Methods of preparation of camptothecin analogs |
DK1251125T3 (da) * | 1995-06-21 | 2006-04-18 | Sod Conseils Rech Applic | Hidtil ukendte camptothecin-analoger, fremgangsmåde til fremstilling heraf, anvendelse heraf som lægemidler og farmaceutiske præparater indeholdende disse |
-
1996
- 1996-12-20 FR FR9615774A patent/FR2757514B1/fr not_active Expired - Fee Related
-
1997
- 1997-05-12 UA UA99063449A patent/UA57758C2/uk unknown
- 1997-12-05 PL PL97334125A patent/PL188181B1/pl not_active IP Right Cessation
- 1997-12-05 AT AT97950236T patent/ATE248177T1/de active
- 1997-12-05 KR KR10-1999-7005603A patent/KR100516874B1/ko not_active IP Right Cessation
- 1997-12-05 BR BR9714170-4A patent/BR9714170A/pt not_active Application Discontinuation
- 1997-12-05 PT PT97950236T patent/PT946567E/pt unknown
- 1997-12-05 RU RU99115829/04A patent/RU2194051C2/ru not_active IP Right Cessation
- 1997-12-05 WO PCT/FR1997/002218 patent/WO1998028305A1/fr active IP Right Grant
- 1997-12-05 EP EP97950236A patent/EP0946567B1/de not_active Expired - Lifetime
- 1997-12-05 AU AU53265/98A patent/AU734485B2/en not_active Ceased
- 1997-12-05 DE DE69724453T patent/DE69724453T2/de not_active Expired - Lifetime
- 1997-12-05 ES ES97950236T patent/ES2206761T3/es not_active Expired - Lifetime
- 1997-12-05 NZ NZ335939A patent/NZ335939A/xx not_active IP Right Cessation
- 1997-12-05 HU HU9904210A patent/HUP9904210A3/hu unknown
- 1997-12-05 CA CA002275351A patent/CA2275351C/fr not_active Expired - Fee Related
- 1997-12-05 JP JP52844898A patent/JP3576175B2/ja not_active Expired - Fee Related
- 1997-12-05 CZ CZ0220599A patent/CZ299795B6/cs not_active IP Right Cessation
- 1997-12-05 MX MXPA99005776A patent/MXPA99005776A/es not_active IP Right Cessation
- 1997-12-05 CN CN97180815A patent/CN1097056C/zh not_active Expired - Fee Related
- 1997-12-05 DK DK97950236T patent/DK0946567T3/da active
- 1997-12-10 ZA ZA9711129A patent/ZA9711129B/xx unknown
- 1997-12-17 MY MYPI97006088A patent/MY119473A/en unknown
- 1997-12-19 AR ARP970106043A patent/AR008543A1/es active IP Right Grant
-
1999
- 1999-06-18 NO NO19992998A patent/NO326464B1/no not_active IP Right Cessation
-
2000
- 2000-07-04 HK HK00104036A patent/HK1024695A1/xx not_active IP Right Cessation
-
2003
- 2003-11-26 JP JP2003395513A patent/JP2004115535A/ja not_active Withdrawn
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20111205 |