HK1020756A1 - Use of angiogenic factor vegf145 in treating cardiovascular disease - Google Patents

Use of angiogenic factor vegf145 in treating cardiovascular disease

Info

Publication number
HK1020756A1
HK1020756A1 HK99105958A HK99105958A HK1020756A1 HK 1020756 A1 HK1020756 A1 HK 1020756A1 HK 99105958 A HK99105958 A HK 99105958A HK 99105958 A HK99105958 A HK 99105958A HK 1020756 A1 HK1020756 A1 HK 1020756A1
Authority
HK
Hong Kong
Prior art keywords
vegf145
derivatives
novel
protein products
vegf
Prior art date
Application number
HK99105958A
Other languages
English (en)
Inventor
Gera Neufeld
Eli Keshet
Israel Vlodavsky
Zoya Poltorak
Original Assignee
Technion Res & Dev Co Ltd
Collateral Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Res & Dev Co Ltd, Collateral Therapeutics filed Critical Technion Res & Dev Co Ltd
Publication of HK1020756A1 publication Critical patent/HK1020756A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
HK99105958A 1996-09-06 1999-12-17 Use of angiogenic factor vegf145 in treating cardiovascular disease HK1020756A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2553796P 1996-09-06 1996-09-06
US08/784,551 US6013780A (en) 1996-09-06 1997-01-21 VEGF145 expression vectors
PCT/US1997/015471 WO1998010071A1 (fr) 1996-09-06 1997-09-04 Facteur angiogenique et utilisation de celui-ci dans le traitement de maladies cardiovasculaires

Publications (1)

Publication Number Publication Date
HK1020756A1 true HK1020756A1 (en) 2000-05-19

Family

ID=26699889

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99105958A HK1020756A1 (en) 1996-09-06 1999-12-17 Use of angiogenic factor vegf145 in treating cardiovascular disease

Country Status (15)

Country Link
US (3) US6013780A (fr)
EP (1) EP0925360B1 (fr)
JP (1) JP2001500728A (fr)
KR (1) KR20000068506A (fr)
CN (1) CN1236390A (fr)
AT (1) ATE256186T1 (fr)
AU (1) AU737898B2 (fr)
CA (1) CA2265252C (fr)
DE (1) DE69726741T2 (fr)
EA (1) EA004646B1 (fr)
ES (1) ES2212127T3 (fr)
HK (1) HK1020756A1 (fr)
IL (1) IL128727A (fr)
NZ (1) NZ334508A (fr)
WO (1) WO1998010071A1 (fr)

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US7097832B1 (en) * 1999-03-30 2006-08-29 Myocardial Therapeutics, Inc. Intramyocardial injection of autologous bone marrow
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AU5023300A (en) 1999-05-20 2000-12-12 Scios Inc. Vascular endothelial growth factor variants
EP1183357A2 (fr) * 1999-05-20 2002-03-06 Scios Inc. Dimeres, facteurs de croissance de l'endothelium vasculaire
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US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US7037332B2 (en) * 2000-03-15 2006-05-02 Orbus Medical Technologies, Inc. Medical device with coating that promotes endothelial cell adherence
US8460367B2 (en) 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
CA2404616C (fr) 2000-04-12 2009-08-18 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Utilisation de vegf et d'homologues pour traiter des troubles du neurone
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CA2419245A1 (fr) * 2000-08-17 2002-02-21 Keiya Ozawa Distribution de facteurs angiogeniques a mediation assuree par virus associe aux adenovirus
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
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US7067317B2 (en) 2000-12-07 2006-06-27 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US7026462B2 (en) 2000-12-07 2006-04-11 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US20050142130A1 (en) * 2001-01-04 2005-06-30 Roks Antonius J.M. Use of angiotensin-(1-7) for preventing and/or reducing the formation of neointima
EP1399484B1 (fr) * 2001-06-28 2010-08-11 Domantis Limited Ligand a double specificite et son utilisation
WO2004003019A2 (fr) * 2002-06-28 2004-01-08 Domantis Limited Ligand
US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
NZ543755A (en) 2001-08-29 2008-04-30 Genentech Inc Bv8 nucleic acids and polypeptides with mitogenic activity
JP2005502672A (ja) 2001-08-29 2005-01-27 リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド サイモシンβ４、類似体、アイソフォームおよびその他の誘導体を用いて心筋障害の発生前、発生中または発生後に発生する炎症、損傷およびその他の変化を治癒または予防する方法
US6753071B1 (en) * 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
US20040009937A1 (en) * 2002-01-31 2004-01-15 Wei Chen Methods and composition for delivering nucleic acids and/or proteins to the respiratory system
US20050075298A1 (en) * 2002-01-31 2005-04-07 Wei Chen Methods and composition for delivering nucleic acids and/or proteins to the intestinal mucosa
US20040043003A1 (en) * 2002-01-31 2004-03-04 Wei Chen Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions
AU2003232152A1 (en) * 2002-05-30 2003-12-19 Myocardial Therapeutics, Inc. Intramyocardial injection of autologous bone marrow
US7696320B2 (en) 2004-08-24 2010-04-13 Domantis Limited Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
US9321832B2 (en) * 2002-06-28 2016-04-26 Domantis Limited Ligand
CN100398652C (zh) * 2002-12-09 2008-07-02 图尔金株式会社 调节性锌指蛋白
WO2004055156A2 (fr) * 2002-12-17 2004-07-01 Technion Research And Development Foundation Ltd. Variante de facteur de croissance endotheliale vasculaire (vegf) manquant d'activite de liaison du vegfr-1 et son utilisation dans l'activation de l'endothelisation et la prevention de la restenose intra-stent
JP2006523090A (ja) * 2002-12-27 2006-10-12 ドマンティス リミテッド リガンドに、そしてリガンド受容体に特異的な二重特異性単一ドメイン抗体
EP1615659B1 (fr) 2003-03-12 2014-04-16 Genentech, Inc. Utilisation de bv8 et/ou de eg-vegf pour promouvoir l'hématopoièse
BRPI0610499A2 (pt) * 2005-04-12 2010-06-22 Intradigm Corp moléculas de ácido nucléico , composições e usos das referidas moléculas
US7893244B2 (en) * 2005-04-12 2011-02-22 Intradigm Corporation Composition and methods of RNAi therapeutics for treatment of cancer and other neovascularization diseases
KR100772424B1 (ko) * 2005-08-05 2007-11-01 박기랑 ⅤＥＧＦ－Ａ，ⅤＥＧＦ－Ｂ，및 ⅤＥＧＦ－Ｃ의 안티센스 ｃＤＮＡ를 함유하는 재조합 아데노-연관 바이러스 및 ⅤＥＧＦＲ 트렁케이티드 솔루블 ｃＤＮＡ를 함유하는 재조합 아데노-연관 바이러스를 포함하는 암의 유전자 치료제
EP1957536A2 (fr) * 2005-12-01 2008-08-20 Domantis Limited Formats d'anticorps a domaine non competitif qui lient le recepteur type 1 d'interleukine 1
MX2009012968A (es) * 2007-06-06 2010-04-01 Domantis Ltd Polipeptidos, dominios variables de anticuerpo y antagonistas.
ES2440751T3 (es) * 2008-10-07 2014-01-30 Boston Scientific Scimed, Inc. Dispositivos médicos para administración de agentes terapéuticos a los lúmenes corporales
CN110760542B (zh) * 2019-11-18 2022-07-26 天津大学 一种共表达znf580和vegf165双基因的质粒及应用

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US5288846A (en) * 1990-10-19 1994-02-22 The General Hospital Corporation Cell specific gene regulators
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US5652225A (en) * 1994-10-04 1997-07-29 St. Elizabeth's Medical Center Of Boston, Inc. Methods and products for nucleic acid delivery
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
US6013780A (en) * 1996-09-06 2000-01-11 Technion Research & Development Co. Ltd. VEGF145 expression vectors

Also Published As

Publication number Publication date
US6013780A (en) 2000-01-11
CA2265252A1 (fr) 1998-03-12
NZ334508A (en) 2001-03-30
EA199900262A1 (ru) 1999-10-28
AU4247197A (en) 1998-03-26
DE69726741D1 (de) 2004-01-22
US6589782B1 (en) 2003-07-08
IL128727A0 (en) 2005-11-20
JP2001500728A (ja) 2001-01-23
EA004646B1 (ru) 2004-06-24
IL128727A (en) 2007-06-17
CN1236390A (zh) 1999-11-24
ATE256186T1 (de) 2003-12-15
WO1998010071A1 (fr) 1998-03-12
EP0925360A1 (fr) 1999-06-30
CA2265252C (fr) 2005-04-19
KR20000068506A (ko) 2000-11-25
ES2212127T3 (es) 2004-07-16
US6583276B1 (en) 2003-06-24
AU737898B2 (en) 2001-09-06
DE69726741T2 (de) 2004-09-30
EP0925360B1 (fr) 2003-12-10

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070904