HK1019043A1 - Colonic delivery of nicotine to treat inflammatory bowel disease - Google Patents

Colonic delivery of nicotine to treat inflammatory bowel disease

Info

Publication number
HK1019043A1
HK1019043A1 HK99102424A HK99102424A HK1019043A1 HK 1019043 A1 HK1019043 A1 HK 1019043A1 HK 99102424 A HK99102424 A HK 99102424A HK 99102424 A HK99102424 A HK 99102424A HK 1019043 A1 HK1019043 A1 HK 1019043A1
Authority
HK
Hong Kong
Prior art keywords
nicotine
inflammatory bowel
bowel disease
treat inflammatory
colonic delivery
Prior art date
Application number
HK99102424A
Other languages
English (en)
Inventor
William Sandborn
John Rhodes
Peter Rhodes
Brian Kenneth Evans
Original Assignee
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24423169&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1019043(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mayo Foundation filed Critical Mayo Foundation
Publication of HK1019043A1 publication Critical patent/HK1019043A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
HK99102424A 1996-02-09 1999-05-31 Colonic delivery of nicotine to treat inflammatory bowel disease HK1019043A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/605,319 US5846983A (en) 1996-02-09 1996-02-09 Colonic delivery of nicotine to treat inflammatory bowel disease
PCT/GB1997/000369 WO1997028801A1 (fr) 1996-02-09 1997-02-07 Administration de nicotine par le colon en vue de traiter les affections intestinales inflammatoires

Publications (1)

Publication Number Publication Date
HK1019043A1 true HK1019043A1 (en) 2000-01-21

Family

ID=24423169

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102424A HK1019043A1 (en) 1996-02-09 1999-05-31 Colonic delivery of nicotine to treat inflammatory bowel disease

Country Status (21)

Country Link
US (1) US5846983A (fr)
EP (1) EP0893998B2 (fr)
JP (1) JP4283340B2 (fr)
KR (1) KR100458636B1 (fr)
CN (1) CN1127340C (fr)
AT (1) ATE237330T1 (fr)
AU (1) AU718971C (fr)
CA (1) CA2246235C (fr)
CZ (1) CZ293616B6 (fr)
DE (1) DE69720985T3 (fr)
DK (1) DK0893998T4 (fr)
ES (1) ES2196303T5 (fr)
HK (1) HK1019043A1 (fr)
HU (1) HUP9900950A3 (fr)
MX (1) MX9806354A (fr)
MY (1) MY122023A (fr)
PL (1) PL187914B1 (fr)
PT (1) PT893998E (fr)
SK (1) SK284539B6 (fr)
WO (1) WO1997028801A1 (fr)
ZA (1) ZA971020B (fr)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889028A (en) * 1996-02-09 1999-03-30 Mayo Foundation For Medical Education And Research Colonic delivery of nicotine to treat inflammatory bowel disease
GB9614902D0 (en) * 1996-07-16 1996-09-04 Rhodes John Sustained release composition
US6268386B1 (en) * 1998-06-25 2001-07-31 Marshall Anlauf Thompson Nicotine beverage
EP1105141B1 (fr) * 1998-08-06 2003-11-05 Wolfgang Stremmel Phosphatidylcholine en tant que medicament a action protectrice des muqueuses
JP2002536404A (ja) * 1999-02-12 2002-10-29 ワシントン ユニバーシティー 炎症性腸疾患を治療するための好中球機能の刺激
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
CA2389650C (fr) * 1999-11-01 2008-12-09 Rodeva Limited Composition destinee au traitement de la constipation et du syndrome du colon irritable
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
IT1318625B1 (it) 2000-07-14 2003-08-27 Roberto Valducci Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
AU2001282064B2 (en) * 2000-08-03 2007-02-01 Antares Pharma Ipl Ag Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
CA2341952A1 (fr) 2001-03-23 2002-09-23 Universite Laval Agonistes du recepteur de la nicotine pour le traitement des maladies pulmonaires inflammatoires
US20050130990A1 (en) * 2001-03-23 2005-06-16 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
US20060204598A1 (en) * 2001-12-10 2006-09-14 Thompson Marshall A Nicotine-alternative compositions and methods of producing such compositions
US20050131031A1 (en) * 2001-12-10 2005-06-16 Thompson Marshall A. Method of producing a nicotine composition
US20030108592A1 (en) * 2001-12-10 2003-06-12 Thompson Marshall Anlauf Method of producing a nicotine composition
US20100160376A1 (en) * 2001-12-10 2010-06-24 Marshall Anlauf Thompson Nicotine-alternative compositions and methods of producing such compositions
US7091357B2 (en) 2001-12-26 2006-08-15 University Of Kentucky Research Foundation Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies
US8557804B2 (en) 2002-03-25 2013-10-15 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
US8039459B2 (en) * 2004-07-15 2011-10-18 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
KR101108439B1 (ko) 2002-10-25 2012-01-31 포믹스 리미티드 화장료 및 약제용 거품제
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8084432B2 (en) * 2003-02-13 2011-12-27 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of pouchitis
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
JP5619337B2 (ja) 2003-10-10 2014-11-05 フェリング ビー．ブイ． 皮膚残渣を最小限に抑えるための経皮的医薬製剤
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
US7780981B2 (en) 2004-09-13 2010-08-24 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20100092616A1 (en) * 2005-01-27 2010-04-15 Marshall Anlauf Thompson Method of producing a nicotine composition
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
CN101426475A (zh) 2006-04-21 2009-05-06 安塔雷斯制药Ipl股份公司 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
WO2008103818A1 (fr) * 2007-02-21 2008-08-28 University Of Louisville Research Foundation Compositions thérapeutiques à base de cotinine
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (fr) 2007-11-30 2009-06-04 Foamix Ltd. Peroxyde de benzoyle contenant de la mousse
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (fr) 2007-12-07 2009-06-11 Foamix Ltd. Porteurs, formulations, procédés pour formuler des agents actifs instables pour application externe et utilisations associées
CA2712120A1 (fr) 2008-01-14 2009-07-23 Foamix Ltd. Compositions pharmaceutiques pouvant mousser de poloxamere avec des agents actifs et/ou des cellules therapeutiques, et utilisations
EP2100598A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100599A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
CA2760186C (fr) 2009-04-28 2019-10-29 Foamix Ltd. Vehicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
CA2769677A1 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes a base d'agents non tensioactifs non polymeres, mousses legeres, et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
EP2482788B1 (fr) 2009-10-02 2022-12-14 Journey Medical Corporation Compositions de tétracycline à usage topique
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
EP2510928A1 (fr) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
WO2013006643A1 (fr) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions et méthodes de traitement de symptômes chez des patients atteints de la maladie de parkinson
JP6855165B2 (ja) * 2012-06-15 2021-04-07 コナリス リサーチ インスティチュート アーゲー ニコチン酸および／もしくはニコチンアミドならびに／またはトリプトファンを含有する、腸内微生物叢によい影響を及ぼすための医薬組成物
EP3079675B1 (fr) 2013-12-13 2020-02-12 CONARIS research institute AG Composition pharmaceutique contenant de l'acide nicotinique et/ou de la nicotinamide et son utilisation destinée à influencer de manière bénéfique les taux de lipide dans le sang en modifiant la microbiote intestinale
MX2016007323A (es) 2013-12-13 2016-09-09 Conaris Res Inst Ag Una composicion farmaceutica que contiene combinaciones de nicotinamida y acido 5-aminosalicilico para influir beneficiosamente en la microflora intestinal y/o para tratar la inflamacion gastrointestinal.
GB201400442D0 (en) * 2014-01-10 2014-02-26 Sigmoid Pharma Ltd Compositions for use in the treatment of ulcerative colitis
CA2974324A1 (fr) 2015-01-28 2016-08-04 Zita S. Netzel Procedes et systemes d'administration de medicament
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
CA3049529A1 (fr) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Dispositifs et methodes d'administration transdermique de medicament
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
CN115089641B (zh) * 2022-05-25 2023-07-25 西安交通大学医学院第一附属医院 一种难治型溃疡性结肠炎灌肠剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3645036A1 (de) * 1986-11-18 1989-01-05 Forschungsgesellschaft Rauchen Nikotinhaltiges mittel
US4855142A (en) * 1987-02-27 1989-08-08 Ciba-Geigy Corporation Pharmaceutical plaster
IE62662B1 (en) * 1989-01-06 1995-02-22 Elan Corp Plc Use of nicotine in the treatment of conditions susceptible to said treatment
DE69117955T2 (de) * 1990-07-20 1996-09-19 Tillotts Pharma Ag, Ziefen Produkte und verfahren zur behandlung des verdauungskanals
GEP19971086B (en) * 1991-02-22 1997-12-02 Tillotts Pharma Ag Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
KR0121127B1 (ko) * 1994-05-09 1997-11-13 강박광 이온성 고분자 네트웍을 갖는 피부약물전달체계
US5604231A (en) * 1995-01-06 1997-02-18 Smith; Carr J. Pharmaceutical compositions for prevention and treatment of ulcerative colitis
US5532254A (en) † 1995-06-07 1996-07-02 Eli Lilly And Company Modulation of calcium channels using benzothiophenes
GB9614902D0 (en) * 1996-07-16 1996-09-04 Rhodes John Sustained release composition

Also Published As

Publication number Publication date
DE69720985D1 (de) 2003-05-22
ZA971020B (en) 1997-11-05
ATE237330T1 (de) 2003-05-15
AU718971B2 (en) 2000-05-04
KR19990082429A (ko) 1999-11-25
MY122023A (en) 2006-03-31
CZ245198A3 (cs) 1999-05-12
CA2246235A1 (fr) 1997-08-14
SK106898A3 (en) 2000-12-11
SK284539B6 (sk) 2005-06-02
CA2246235C (fr) 2007-06-12
CN1210466A (zh) 1999-03-10
AU1729497A (en) 1997-08-28
PT893998E (pt) 2003-07-31
CN1127340C (zh) 2003-11-12
PL187914B1 (pl) 2004-10-29
CZ293616B6 (cs) 2004-06-16
AU718971C (en) 2008-01-31
EP0893998B2 (fr) 2007-12-12
HUP9900950A2 (hu) 1999-08-30
JP2000505430A (ja) 2000-05-09
JP4283340B2 (ja) 2009-06-24
DE69720985T2 (de) 2004-02-05
DK0893998T3 (da) 2003-08-11
DE69720985T3 (de) 2008-05-29
US5846983A (en) 1998-12-08
KR100458636B1 (ko) 2005-01-15
ES2196303T3 (es) 2003-12-16
EP0893998B1 (fr) 2003-04-16
DK0893998T4 (da) 2008-05-05
ES2196303T5 (es) 2008-05-01
HUP9900950A3 (en) 2000-01-28
EP0893998A1 (fr) 1999-02-03
WO1997028801A1 (fr) 1997-08-14
MX9806354A (es) 1998-10-31
PL328430A1 (en) 1999-02-01

Similar Documents

Publication Publication Date Title
ZA971020B (en) Colonic delivery of nicotine to treat inflammatory bowel disease.
IL209703A0 (en) Controlled release hydrocodone formulations
AU1079701A (en) Oral transmucosal drug dosage using solid solution
WO2002045703A3 (fr) Composes organiques
NZ516347A (en) Indanyl-substituted benzenecarboxamides, process for their preparation, their use as a medicament and pharmaceutical formulations containing them
EP0966966A3 (fr) Forme posologique de néfadozone
NZ524138A (en) Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents
GR1003658B (el) Δισκιο μητρας που καθιστα δυνατη την παρατεταμενη απελευθερωση της τριμεταζιδινης μετα χορηγηση δια της στοματικης οδου
PL1608349T3 (pl) Układ do ustnego dostarczania zawierający środek przeciwbakteryjny i środek przeciwzapalny
HK1045464A1 (en) Use of sulfodehydroabietic acid for the treatment of inflammatory bowel disease
IL143985A0 (en) New use of melagatran
WO2000069520A3 (fr) Utilisation d'azathioprine topique pour le traitement de maladies intestinales inflammatoires
BG106180A (en) Pharmaceutical composition containing sibutramine and orlistat
GB9924636D0 (en) Laxative preparation
BG104692A (en) Extended release tiagabine formulation
MX9707391A (es) Composiciones de azatioprina para administracion colonica.
WO2001007013A3 (fr) Substances et procedes de liberation controlee d'agents therapeutiques contenant des fractions thioamide par liaison a des polymeres contenant des thiols
CO4910116A1 (es) Formulacion de liberacion controlada para farmacos basicos escasamente solubles
AU4918900A (en) Interferon-beta use in the treatment of ewing's family of tumors
RU2003115800A (ru) Способ интраоперационной профилактики гнойно-воспалительных осложнений трансуретральных манипуляций и операций

Legal Events

Date Code Title Description
PF Patent in force
AM Amended specification (according sect 146 of patent law)

Free format text: AMEND JOURNAL DATED 01-02-2008 73] MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 54] COLONIC DELIVERY OF NICOTINE TO TREAT INFLAMMATORY BOWEL DISEASE

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080207