HK1017380A1 - Method of purifying thrombin-like protease enzymesobtained from snake venom. - Google Patents

Method of purifying thrombin-like protease enzymesobtained from snake venom.

Info

Publication number
HK1017380A1
HK1017380A1 HK99102524A HK99102524A HK1017380A1 HK 1017380 A1 HK1017380 A1 HK 1017380A1 HK 99102524 A HK99102524 A HK 99102524A HK 99102524 A HK99102524 A HK 99102524A HK 1017380 A1 HK1017380 A1 HK 1017380A1
Authority
HK
Hong Kong
Prior art keywords
enzymesobtained
protease
snake venom
purifying thrombin
thrombin
Prior art date
Application number
HK99102524A
Other languages
English (en)
Inventor
Margarete Schwarz
Wolfgang Zahn
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of HK1017380A1 publication Critical patent/HK1017380A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6418—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals from snakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK99102524A 1996-02-26 1999-06-10 Method of purifying thrombin-like protease enzymesobtained from snake venom. HK1017380A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19607210A DE19607210A1 (de) 1996-02-26 1996-02-26 Verfahren zur Reinigung von thrombinähnlichen Proteasen aus Schlangengiften
PCT/EP1997/000755 WO1997032015A1 (de) 1996-02-26 1997-02-18 Verfahren zur reinigung von thrombinähnlichen proteasen aus schlangengiften

Publications (1)

Publication Number Publication Date
HK1017380A1 true HK1017380A1 (en) 1999-11-19

Family

ID=7786490

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102524A HK1017380A1 (en) 1996-02-26 1999-06-10 Method of purifying thrombin-like protease enzymesobtained from snake venom.

Country Status (32)

Country Link
US (1) US6200791B1 (ru)
EP (1) EP0883684B1 (ru)
JP (1) JP3817269B2 (ru)
KR (1) KR100493835B1 (ru)
CN (1) CN1188517C (ru)
AR (1) AR005995A1 (ru)
AT (1) ATE283350T1 (ru)
AU (1) AU711650B2 (ru)
BG (1) BG64875B1 (ru)
BR (1) BR9707738A (ru)
CO (1) CO4771158A1 (ru)
CZ (1) CZ292482B6 (ru)
DE (2) DE19607210A1 (ru)
ES (1) ES2233997T3 (ru)
HK (1) HK1017380A1 (ru)
HR (1) HRP970108B1 (ru)
HU (1) HU225489B1 (ru)
ID (1) ID16046A (ru)
IL (1) IL125395A (ru)
MX (1) MX9806304A (ru)
MY (1) MY130458A (ru)
NO (1) NO319561B1 (ru)
NZ (1) NZ331120A (ru)
PL (1) PL186211B1 (ru)
PT (1) PT883684E (ru)
RU (1) RU2186849C2 (ru)
SK (1) SK284874B6 (ru)
TR (1) TR199801668T2 (ru)
TW (1) TW505696B (ru)
UA (1) UA46831C2 (ru)
WO (1) WO1997032015A1 (ru)
ZA (1) ZA971597B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102173C (zh) * 1999-03-26 2003-02-26 福建医科大学 蕲蛇酶及其生产工艺
US20030219431A1 (en) * 2002-05-24 2003-11-27 Empire Pharmaceuticals, Inc. Treatment of neuronal and neurological damage associated with spinal cord injury
EP2043767B1 (en) 2006-07-14 2020-03-25 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses
CN103160486A (zh) * 2013-04-02 2013-06-19 黑龙江迪龙制药有限公司 一种猪凝血酶的制备方法
CN109929020A (zh) * 2017-12-15 2019-06-25 浙江京新药业股份有限公司 一种眼镜蛇毒的纯化方法及其产品
CN108559740B (zh) * 2018-05-12 2021-05-18 吉林天衡康泰生物技术有限公司 重组安克洛酶及工业规模制备方法和治疗急性脑梗的应用
CN109652398B (zh) * 2018-12-29 2021-07-20 上海太阳生物技术有限公司 凝血因子ⅹ激活剂rvv-ⅹ的制备方法及制得的rvv-ⅹ
CN110016471B (zh) * 2019-04-10 2020-10-02 北京博康宁生物医药科技有限公司 重组安克洛酶及工业规模制备和纯化方法及其组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094301A (en) * 1964-02-21 1967-12-06 Nat Res Dev Improvements relating to anticoagulants
GB1177506A (en) * 1964-02-21 1970-01-14 Nat Res Dev Improvements relating to Anticoagulants.
GB1293793A (en) 1969-04-28 1972-10-25 Chrysler United Kingdom Ltd Fo Improvements in or relating to valves
US3743722A (en) * 1971-07-14 1973-07-03 Abbott Lab Anti-coagulant isolation
US3879369A (en) 1972-05-12 1975-04-22 Abbott Lab Anti-coagulant isolation from malayan pit viper using affinity chromatography
GB1472574A (en) 1973-09-03 1977-05-04 Biochimici Fargal Pharmasint S Process for the extraction of components having anticoagulant activity -in vivo- from snake venoms and related products
NL7605805A (nl) * 1976-05-28 1977-11-30 Stichting Rega V Z W Werkwijze voor het zuiveren van interferon.
CH626917A5 (ru) 1976-08-17 1981-12-15 Pentapharm Ag
JPS5569595A (en) * 1978-11-20 1980-05-26 Suguru Abe Novel substance having fibrinolytic activity, remedy for thrombotic embolic disease comprising it, and its preparation
EP0328256A1 (en) * 1988-01-21 1989-08-16 Owens-Corning Fiberglas Corporation Glass fibers coated with agarose for use as column packing or chromatographic media for bioseparations
US5712117A (en) * 1995-02-08 1998-01-27 Zymogenetics, Inc. Cytoplasmic antiproteinase-2 and coding sequences

Also Published As

Publication number Publication date
KR100493835B1 (ko) 2005-12-21
ES2233997T3 (es) 2005-06-16
DE59712093D1 (de) 2004-12-30
IL125395A0 (en) 1999-03-12
EP0883684A1 (de) 1998-12-16
US6200791B1 (en) 2001-03-13
SK284874B6 (sk) 2006-01-05
CN1188517C (zh) 2005-02-09
CN1212013A (zh) 1999-03-24
BG102663A (en) 1999-04-30
KR19990087247A (ko) 1999-12-15
MX9806304A (es) 1998-11-30
BR9707738A (pt) 1999-07-27
CZ269798A3 (cs) 1999-01-13
MY130458A (en) 2007-06-29
SK113298A3 (en) 1999-01-11
ATE283350T1 (de) 2004-12-15
WO1997032015A1 (de) 1997-09-04
IL125395A (en) 2001-04-30
AR005995A1 (es) 1999-07-21
NZ331120A (en) 2000-01-28
TR199801668T2 (xx) 1999-02-22
ID16046A (id) 1997-08-28
TW505696B (en) 2002-10-11
NO983893L (no) 1998-08-25
CZ292482B6 (cs) 2003-09-17
AU1791397A (en) 1997-09-16
HUP9900505A3 (en) 2001-03-28
HRP970108A2 (en) 1998-04-30
JP2000505304A (ja) 2000-05-09
BG64875B1 (bg) 2006-07-31
EP0883684B1 (de) 2004-11-24
PL186211B1 (pl) 2003-11-28
HRP970108B1 (en) 2002-02-28
UA46831C2 (uk) 2002-06-17
RU2186849C2 (ru) 2002-08-10
CO4771158A1 (es) 1999-04-30
DE19607210A1 (de) 1997-08-28
PL328568A1 (en) 1999-02-01
NO983893D0 (no) 1998-08-25
HU225489B1 (en) 2006-12-28
PT883684E (pt) 2005-04-29
AU711650B2 (en) 1999-10-21
JP3817269B2 (ja) 2006-09-06
HUP9900505A2 (hu) 1999-06-28
NO319561B1 (no) 2005-08-29
ZA971597B (en) 1998-08-25

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Legal Events

Date Code Title Description
AS Change of ownership

Owner name: KNOLL GMBH

Free format text: FORMER OWNER(S): KNOLL AKTIENGESELLSCHAFT

Owner name: ABBOTT GMBH

Free format text: FORMER OWNER(S): KNOLL GMBH

Owner name: ABBOTT GMBH & CO. KG

Free format text: FORMER OWNER(S): ABBOTT GMBH

AS Change of ownership

Owner name: ABBOTT GMBH

Free format text: FORMER OWNER(S): KNOLL GMBH

Owner name: ABBOTT GMBH & CO. KG

Free format text: FORMER OWNER(S): ABBOTT GMBH

Owner name: KNOLL GMBH

Free format text: FORMER OWNER(S): KNOLL AG

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20120218