HK1015273A1 - Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral. - Google Patents

Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral.

Info

Publication number
HK1015273A1
HK1015273A1 HK99100417A HK99100417A HK1015273A1 HK 1015273 A1 HK1015273 A1 HK 1015273A1 HK 99100417 A HK99100417 A HK 99100417A HK 99100417 A HK99100417 A HK 99100417A HK 1015273 A1 HK1015273 A1 HK 1015273A1
Authority
HK
Hong Kong
Prior art keywords
antiretroviral
potentiating
carnitine
derivatives
ceramide levels
Prior art date
Application number
HK99100417A
Other languages
English (en)
Inventor
Sonia Moretti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of HK1015273A1 publication Critical patent/HK1015273A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK99100417A 1995-08-03 1999-02-02 Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral. HK1015273A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95RM000544A IT1277897B1 (it) 1995-08-03 1995-08-03 Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
PCT/IT1996/000146 WO1997005864A2 (en) 1995-08-03 1996-07-19 Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral drugs

Publications (1)

Publication Number Publication Date
HK1015273A1 true HK1015273A1 (en) 1999-10-15

Family

ID=11403512

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100417A HK1015273A1 (en) 1995-08-03 1999-02-02 Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral.

Country Status (19)

Country Link
US (2) US6040346A (ko)
EP (1) EP0839033B1 (ko)
JP (1) JPH11510181A (ko)
KR (1) KR100412532B1 (ko)
CN (1) CN1161116C (ko)
AR (1) AR004503A1 (ko)
AT (1) ATE260654T1 (ko)
AU (1) AU719906B2 (ko)
BR (1) BR9609947A (ko)
CA (1) CA2228266C (ko)
DE (1) DE69631768T2 (ko)
DK (1) DK0839033T3 (ko)
ES (1) ES2216050T3 (ko)
HK (1) HK1015273A1 (ko)
IT (1) IT1277897B1 (ko)
PT (1) PT839033E (ko)
RU (2) RU2203047C2 (ko)
TW (1) TW464493B (ko)
WO (1) WO1997005864A2 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
US20010025027A1 (en) * 2000-03-07 2001-09-27 Sonis Stephen T. Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation
IT1317938B1 (it) * 2000-11-17 2003-07-15 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento di alterazioni delmetabolismo lipidico, delle forme allergiche e per attivare le difese
EP2586438A1 (en) * 2011-10-28 2013-05-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Compound useful for preventing cognitive deficit disorders in a new born from HIV-seropositive pregnant female who is in treatment with azidothymidine
RU2559179C1 (ru) * 2014-03-24 2015-08-10 Илья Александрович Марков Фармацевтическая композиция для лечения тяжелых форм вирусных инфекций в виде таблеток
DE202017102551U1 (de) 2017-04-28 2017-06-01 E-Lead Electronic Co., Ltd. Verstellbares Allzeit-Head-Up-Displaysystem
WO2021221741A1 (en) * 2020-04-28 2021-11-04 Lonza Consumer Health Inc. Nutritional composition comprising carnitine and method for treating or preventing an infection in a mammal

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
IE903343A1 (en) * 1989-09-18 1991-04-10 Smithkline Beecham Corp FORMULATION FOR SOLUBLE sT4 FOR TREATMENT OF HIV INFECTION
DE69033521T2 (de) * 1989-12-29 2000-08-31 B. Braun Medical Inc., Bethlehem Verwendung von arginin als immunstimulator
IT1255039B (it) * 1992-03-11 1995-10-13 Sigma Tau Ind Farmaceuti Impiego di l-carnitina nel trattamento di pazienti hiv-sieropositivi presentanti deficit di carnitina.
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1277898B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1283951B1 (it) * 1996-03-15 1998-05-07 Mendes Srl Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di

Also Published As

Publication number Publication date
PT839033E (pt) 2004-07-30
KR100412532B1 (ko) 2004-06-10
CN1193912A (zh) 1998-09-23
EP0839033B1 (en) 2004-03-03
AU6469096A (en) 1997-03-05
JPH11510181A (ja) 1999-09-07
EP0839033A2 (en) 1998-05-06
TW464493B (en) 2001-11-21
ES2216050T3 (es) 2004-10-16
DE69631768T2 (de) 2005-01-13
BR9609947A (pt) 1999-02-02
ITRM950544A1 (it) 1997-02-03
US20040039054A1 (en) 2004-02-26
CA2228266C (en) 2009-05-12
ITRM950544A0 (it) 1995-08-03
US6040346A (en) 2000-03-21
AR004503A1 (es) 1998-12-16
AU719906B2 (en) 2000-05-18
ATE260654T1 (de) 2004-03-15
KR19990036149A (ko) 1999-05-25
RU2269340C2 (ru) 2006-02-10
IT1277897B1 (it) 1997-11-12
MX9800915A (es) 1998-10-31
DK0839033T3 (da) 2004-06-21
CN1161116C (zh) 2004-08-11
DE69631768D1 (de) 2004-04-08
WO1997005864A3 (en) 1997-04-17
WO1997005864A2 (en) 1997-02-20
CA2228266A1 (en) 1997-02-20
RU2203047C2 (ru) 2003-04-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110719