HK1011973A1 - Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-n-oxides process for their preparation and their use as medicaments - Google Patents

Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-n-oxides process for their preparation and their use as medicaments

Info

Publication number
HK1011973A1
HK1011973A1 HK98113073A HK98113073A HK1011973A1 HK 1011973 A1 HK1011973 A1 HK 1011973A1 HK 98113073 A HK98113073 A HK 98113073A HK 98113073 A HK98113073 A HK 98113073A HK 1011973 A1 HK1011973 A1 HK 1011973A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
pyridine
bond
opt
sic
Prior art date
Application number
HK98113073A
Other languages
English (en)
Inventor
Klaus Weidmann
Martin Bickel
Volkmar Gunzler-Pukall
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HK1011973A1 publication Critical patent/HK1011973A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK98113073A 1994-03-25 1998-12-10 Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-n-oxides process for their preparation and their use as medicaments HK1011973A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410480A DE4410480A1 (de) 1994-03-25 1994-03-25 Sulfonamidocarbonylpyridin-2-carbonsäureesteramide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
HK1011973A1 true HK1011973A1 (en) 1999-07-23

Family

ID=6513896

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113073A HK1011973A1 (en) 1994-03-25 1998-12-10 Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-n-oxides process for their preparation and their use as medicaments

Country Status (20)

Country Link
US (1) US5620996A (ko)
EP (1) EP0673932B1 (ko)
JP (1) JPH07278110A (ko)
KR (1) KR950032126A (ko)
AT (1) ATE193702T1 (ko)
AU (1) AU688450B2 (ko)
CA (1) CA2145475A1 (ko)
CZ (1) CZ289536B6 (ko)
DE (2) DE4410480A1 (ko)
DK (1) DK0673932T3 (ko)
ES (1) ES2146676T3 (ko)
FI (1) FI951387A (ko)
GR (1) GR3033706T3 (ko)
HK (1) HK1011973A1 (ko)
HU (1) HUT72598A (ko)
NO (1) NO304265B1 (ko)
NZ (1) NZ270784A (ko)
PL (1) PL180678B1 (ko)
PT (1) PT673932E (ko)
ZA (1) ZA952409B (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE256113T1 (de) * 1996-03-21 2003-12-15 Lonza Ag Verfahren zur herstellung von arylamiden heteroaromatischer carbonsäuren
SK283920B6 (sk) 1996-03-28 2004-05-04 Lonza Ag Spôsob výroby arylamidov heteroaromatických karboxylových kyselín
DK0806415T3 (da) * 1996-05-09 2000-06-05 Lonza Ag Fremgangsmåde til fremstilling af arylamider af heteroaromatiske carboxylsyrer
US6169183B1 (en) 1996-07-23 2001-01-02 Lonza, Ltd. Process for preparing pyridinecarboxylic esters
CA2209392C (en) * 1996-07-23 2007-02-20 Yves Bessard Process for preparing pyridinecarboxylic esters
DE19742951A1 (de) 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
EP2295060B1 (en) 2001-12-06 2018-10-31 Fibrogen, Inc. Treatment or prevention of ischemic or hypoxic conditions
US20030153503A1 (en) 2001-12-06 2003-08-14 Klaus Stephen J. Methods of increasing endogenous erythropoietin (EPO)
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8124582B2 (en) 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
EP1491527A1 (en) * 2003-06-25 2004-12-29 Bayer CropScience GmbH Process for preparing acylsulfamoylbenzamides
KR20080028918A (ko) 2005-06-15 2008-04-02 피브로겐, 인크. 암의 치료를 위한 화합물과 방법
EP2008461B1 (en) * 2006-03-30 2015-09-16 LG Electronics Inc. A method and apparatus for decoding/encoding a multi-view video signal
ES2705587T3 (es) 2006-06-26 2019-03-26 Akebia Therapeutics Inc Inhibidores de prolil hidroxilasa y métodos de uso
WO2009002533A1 (en) * 2007-06-27 2008-12-31 The Brigham And Women's Hospital, Inc. Inflammatory bowel disease therapies
NO2686520T3 (ko) 2011-06-06 2018-03-17
ES2974273T3 (es) 2013-06-13 2024-06-26 Akebia Therapeutics Inc Composiciones y métodos para tratar la anemia
TWI665190B (zh) 2013-11-15 2019-07-11 阿克比治療有限公司 {[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基}乙酸之固體型式,其組合物及用途
WO2016118858A1 (en) 2015-01-23 2016-07-28 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
HUE056958T2 (hu) 2015-04-01 2022-04-28 Akebia Therapeutics Inc Készítmények és eljárások vérszegénység kezelésére
CN105130888A (zh) * 2015-10-09 2015-12-09 中国药科大学 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途
US11713298B2 (en) 2018-05-09 2023-08-01 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
HUT72598A (en) 1996-05-28
GR3033706T3 (en) 2000-10-31
FI951387A0 (fi) 1995-03-23
NO951149D0 (no) 1995-03-24
FI951387A (fi) 1995-09-26
NZ270784A (en) 1997-02-24
CA2145475A1 (en) 1995-09-26
EP0673932B1 (de) 2000-06-07
AU688450B2 (en) 1998-03-12
PL307847A1 (en) 1995-10-02
ZA952409B (en) 1995-11-28
NO304265B1 (no) 1998-11-23
DE59508440D1 (de) 2000-07-13
DK0673932T3 (da) 2000-09-18
EP0673932A1 (de) 1995-09-27
ES2146676T3 (es) 2000-08-16
AU1504395A (en) 1995-10-05
ATE193702T1 (de) 2000-06-15
KR950032126A (ko) 1995-12-20
CZ289536B6 (cs) 2002-02-13
JPH07278110A (ja) 1995-10-24
US5620996A (en) 1997-04-15
PT673932E (pt) 2000-09-29
PL180678B1 (pl) 2001-03-30
NO951149L (no) 1995-09-26
CZ73495A3 (en) 1995-11-15
DE4410480A1 (de) 1995-09-28

Similar Documents

Publication Publication Date Title
HK1011973A1 (en) Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-n-oxides process for their preparation and their use as medicaments
FI951386A (fi) Sulfanamidokarbonyylipyridiini-2-karboksyylihappoamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
ATE164846T1 (de) Neue siliciumhaltige salicylsäurederivate mit abschuppenden eigenschaften
CA2174033A1 (fr) Nouveaux composes pyridiniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
IL109397A0 (en) Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
HUT49349A (en) Process for producing substituted 6-phenyldihydro-3-/2h/-pyridazinone derivatives and pharmaceutical compositions comprising such compounds
HU9802645D0 (en) New metalloproteinase inhibitors, process for producing them, and pharmaceutical compositions containing them
IL119054A0 (en) Substituted 4H-pyrans their preparation and pharmaceutical compositions containing them
HUT40090A (en) New process for production of derivatives of hh-1,2,4-triasole
HUT50469A (en) Process for producing quinolinecarboxylic acids substituted by heterocyclic group
IL115028A0 (en) Cyclohexadiene derivatives their pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20040313

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)