HK1005735A1 - Perhydrothiazepine and perhydroazepine derivatives their preparation and their therapeutic use - Google Patents

Perhydrothiazepine and perhydroazepine derivatives their preparation and their therapeutic use

Info

Publication number
HK1005735A1
HK1005735A1 HK98104837A HK98104837A HK1005735A1 HK 1005735 A1 HK1005735 A1 HK 1005735A1 HK 98104837 A HK98104837 A HK 98104837A HK 98104837 A HK98104837 A HK 98104837A HK 1005735 A1 HK1005735 A1 HK 1005735A1
Authority
HK
Hong Kong
Prior art keywords
perhydrothiazepine
preparation
therapeutic use
perhydroazepine
derivatives
Prior art date
Application number
HK98104837A
Other languages
English (en)
Inventor
Hiroaki Yanagisawa
Sadao Ishihara
Akiko Ando
Hiroyuki Koike
Yasuteru Iijima
Original Assignee
Sankyo Corp Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Corp Limited filed Critical Sankyo Corp Limited
Publication of HK1005735A1 publication Critical patent/HK1005735A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
HK98104837A 1986-04-04 1998-06-03 Perhydrothiazepine and perhydroazepine derivatives their preparation and their therapeutic use HK1005735A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7790486 1986-04-04
JP18357686 1986-08-05

Publications (1)

Publication Number Publication Date
HK1005735A1 true HK1005735A1 (en) 1999-01-22

Family

ID=26418950

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104837A HK1005735A1 (en) 1986-04-04 1998-06-03 Perhydrothiazepine and perhydroazepine derivatives their preparation and their therapeutic use

Country Status (15)

Country Link
US (1) US4778790A (fi)
EP (1) EP0240366B1 (fi)
KR (1) KR930002508B1 (fi)
CN (1) CN1015260B (fi)
AU (1) AU599642B2 (fi)
CA (1) CA1336774C (fi)
DE (1) DE3788888T2 (fi)
DK (1) DK173287A (fi)
ES (1) ES2061490T3 (fi)
FI (1) FI90418C (fi)
HK (1) HK1005735A1 (fi)
HU (1) HU208121B (fi)
IE (1) IE61433B1 (fi)
NZ (1) NZ219884A (fi)
SU (1) SU1598876A3 (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959359A (en) * 1989-10-06 1990-09-25 Hoffmann-La Roche Inc. Phenyl-thiazepinones as calcium regulating agents
CA2146238C (en) * 1992-10-30 2001-03-13 Gary A. Flynn Novel mercaptoacetylamide bicyclic lactam derivatives useful as inhibitors of enkephalinase and ace
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680392A (en) * 1980-08-18 1987-07-14 Merck & Co., Inc. Substituted caprolactam derivatives as antihypertensives
US4629787A (en) * 1980-08-18 1986-12-16 Merck & Co., Inc. Substituted caprolactam derivatives as antihypertensives
GR74635B (fi) * 1980-08-18 1984-06-29 Merck & Co Inc
US4587050A (en) * 1980-08-18 1986-05-06 Merck & Co., Inc. Substituted enantholactam derivatives as antihypertensives
DE3260831D1 (en) * 1981-06-05 1984-10-31 Merck & Co Inc Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
US4512988A (en) * 1984-03-01 1985-04-23 E. R. Squibb & Sons, Inc. Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines
SU1435151A3 (ru) * 1984-04-10 1988-10-30 Санкио Компани Лимитед (Фирма) Способ получени производных пергидротиазепина или их кислотно-аддитивных фармацевтически приемлемых солей
US4666901A (en) * 1984-05-17 1987-05-19 Merck & Co., Inc. Substituted lactams useful as angiotensin converting enzyme inhibitors
JPH0637473B2 (ja) * 1985-10-11 1994-05-18 三共株式会社 ラクタム化合物

Also Published As

Publication number Publication date
DE3788888D1 (de) 1994-03-10
NZ219884A (en) 1989-06-28
FI90418B (fi) 1993-10-29
EP0240366B1 (en) 1994-01-26
EP0240366A3 (en) 1989-05-10
DK173287A (da) 1987-10-05
IE870861L (en) 1987-10-04
AU599642B2 (en) 1990-07-26
US4778790A (en) 1988-10-18
DK173287D0 (da) 1987-04-03
CA1336774C (en) 1995-08-22
EP0240366A2 (en) 1987-10-07
CN1015260B (zh) 1992-01-01
ES2061490T3 (es) 1994-12-16
FI871479A (fi) 1987-10-05
HU208121B (en) 1993-08-30
DE3788888T2 (de) 1994-06-23
FI90418C (fi) 1994-02-10
CN87103684A (zh) 1987-12-09
IE61433B1 (en) 1994-11-02
FI871479A0 (fi) 1987-04-03
HUT47569A (en) 1989-03-28
AU7111587A (en) 1987-10-08
SU1598876A3 (ru) 1990-10-07
KR870010042A (ko) 1987-11-30
KR930002508B1 (ko) 1993-04-03

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)