HK1003435A1 - D4t polymorphic form i process d4t - Google Patents

D4t polymorphic form i process d4t

Info

Publication number
HK1003435A1
HK1003435A1 HK98102471A HK98102471A HK1003435A1 HK 1003435 A1 HK1003435 A1 HK 1003435A1 HK 98102471 A HK98102471 A HK 98102471A HK 98102471 A HK98102471 A HK 98102471A HK 1003435 A1 HK1003435 A1 HK 1003435A1
Authority
HK
Hong Kong
Prior art keywords
polymorphic form
polymorphic
approved
aids
iii
Prior art date
Application number
HK98102471A
Other languages
English (en)
Inventor
Rajesh Babulal Gandhi
Joseph Ballard Bogardus
Peter Michael Garofalo
Timothy Richard Marr
Robert Kevin Perrone
Murray Arthur Kaplan
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HK1003435A1 publication Critical patent/HK1003435A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK98102471A 1995-06-05 1998-03-24 D4t polymorphic form i process d4t HK1003435A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/465,208 US5608048A (en) 1995-06-05 1995-06-05 d4 T polymorphic Form 1 process

Publications (1)

Publication Number Publication Date
HK1003435A1 true HK1003435A1 (en) 1998-10-30

Family

ID=23846880

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98102471A HK1003435A1 (en) 1995-06-05 1998-03-24 D4t polymorphic form i process d4t

Country Status (19)

Country Link
US (1) US5608048A (ja)
EP (1) EP0749969B1 (ja)
JP (1) JP4208976B2 (ja)
KR (1) KR100375957B1 (ja)
CN (1) CN1058723C (ja)
AT (1) ATE205203T1 (ja)
AU (1) AU694653B2 (ja)
CA (1) CA2176181C (ja)
DE (1) DE69614936T2 (ja)
DK (1) DK0749969T3 (ja)
ES (1) ES2160768T3 (ja)
GR (1) GR3036768T3 (ja)
HK (1) HK1003435A1 (ja)
HU (1) HU222285B1 (ja)
IL (1) IL118527A (ja)
MX (1) MX9601957A (ja)
PT (1) PT749969E (ja)
SG (1) SG43372A1 (ja)
TW (1) TW336937B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001285197A1 (en) * 2000-09-06 2002-03-22 Bristol-Myers Squibb Company Stavudine polymorphic form 1 process
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) * 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
WO2007099389A1 (en) * 2005-07-11 2007-09-07 Aurobindo Pharma Limited A new improved process for the preparation of stavudine form i
ITMI20060360A1 (it) * 2006-02-28 2007-09-01 Clariant Lsm Italia Spa Novel method for the preparation of stavudine polymorphic form 1 and form ii
JP5966186B2 (ja) * 2011-02-08 2016-08-10 国立大学法人高知大学 カルサイト単結晶の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US5672698A (en) * 1993-11-15 1997-09-30 Bristol-Myers Squibb Co. Preparation of 2',3'-didehydro-3'-deoxythymidine from 5-methyluridine
US5539099A (en) * 1993-11-15 1996-07-23 Bristol-Myers Squibb Company Process for large-scale preparation of 2',3'-didehydro-2',3'-dideoxynucleosides
US5608049A (en) * 1995-03-10 1997-03-04 Bristol-Myers Squibb Company Preparation of d4T from 5-methyluridine

Also Published As

Publication number Publication date
AU694653B2 (en) 1998-07-23
HU222285B1 (hu) 2003-05-28
EP0749969B1 (en) 2001-09-05
PT749969E (pt) 2001-12-28
JPH08333364A (ja) 1996-12-17
KR970001369A (ko) 1997-01-24
CA2176181A1 (en) 1996-12-06
HU9601517D0 (en) 1996-07-29
TW336937B (en) 1998-07-21
KR100375957B1 (ko) 2003-12-31
IL118527A (en) 2000-07-16
CA2176181C (en) 2007-03-13
DE69614936T2 (de) 2002-04-25
AU5469296A (en) 1996-12-19
US5608048A (en) 1997-03-04
CN1058723C (zh) 2000-11-22
CN1145903A (zh) 1997-03-26
DE69614936D1 (de) 2001-10-11
ES2160768T3 (es) 2001-11-16
ATE205203T1 (de) 2001-09-15
HUP9601517A3 (en) 2000-03-28
SG43372A1 (en) 1997-10-17
EP0749969A3 (en) 1997-03-19
IL118527A0 (en) 1996-10-16
MX9601957A (es) 1997-08-30
EP0749969A2 (en) 1996-12-27
DK0749969T3 (da) 2001-11-26
HUP9601517A2 (en) 1997-05-28
GR3036768T3 (en) 2002-01-31
JP4208976B2 (ja) 2009-01-14

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110604