HK1000801A1 - Compounds having antitumor and antibacterial properties - Google Patents

Compounds having antitumor and antibacterial properties

Info

Publication number
HK1000801A1
HK1000801A1 HK97102378A HK97102378A HK1000801A1 HK 1000801 A1 HK1000801 A1 HK 1000801A1 HK 97102378 A HK97102378 A HK 97102378A HK 97102378 A HK97102378 A HK 97102378A HK 1000801 A1 HK1000801 A1 HK 1000801A1
Authority
HK
Hong Kong
Prior art keywords
antibacterial properties
represent
lower alkyl
groups
antitumor
Prior art date
Application number
HK97102378A
Other languages
English (en)
Inventor
William Alexander Denny
Bruce Charles Baguley
Graham John Atwell
Gordon William Rewcastle
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HK1000801A1 publication Critical patent/HK1000801A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • C07D311/84Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK97102378A 1986-12-23 1997-12-10 Compounds having antitumor and antibacterial properties HK1000801A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NZ21878186 1986-12-23

Publications (1)

Publication Number Publication Date
HK1000801A1 true HK1000801A1 (en) 1998-05-01

Family

ID=19921928

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97102378A HK1000801A1 (en) 1986-12-23 1997-12-10 Compounds having antitumor and antibacterial properties

Country Status (6)

Country Link
EP (1) EP0278176B1 (es)
JP (1) JP2672101B2 (es)
AT (1) ATE102616T1 (es)
DE (1) DE3789299T2 (es)
ES (1) ES2061518T3 (es)
HK (1) HK1000801A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USH1427H (en) * 1988-04-06 1995-04-04 Briet; Phillipe Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
US5238954A (en) * 1989-01-19 1993-08-24 The Upjohn Company Fluorinated flavone acetic acid
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
JP2554447B2 (ja) * 1993-09-14 1996-11-13 ナショナル・サイエンス・カウンシル 新規キサントン化合物
ES2265948T3 (es) * 1999-06-14 2007-03-01 Cancer Research Technology Limited Terapia para el cancer.
JP2001247459A (ja) * 2000-03-03 2001-09-11 Oakland Uniservices Ltd 癌の組み合わせ療法
EP1311262A4 (en) 2000-07-28 2005-06-01 Cancer Rec Tech Ltd COMBINED TREATMENT AGAINST CANCER
KR20030018214A (ko) * 2001-08-27 2003-03-06 한국생명공학연구원 혈관 신생 저해제용 잔테논계 유도체 및 그를 포함하는혈관 신생 저해 조성물
GB0121285D0 (en) 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
GB2386836B (en) 2002-03-22 2006-07-26 Cancer Res Ventures Ltd Anti-cancer combinations
GB2394658A (en) * 2002-11-01 2004-05-05 Cancer Rec Tech Ltd Oral anti-cancer composition
WO2008048117A2 (en) * 2006-10-17 2008-04-24 Auckland Uniservices Limited Synthesis of 5,6-dimethyl-9-oxo-9h-xanthen-4-yl- acetic acid (dmxaa)
CN101195609B (zh) * 2007-09-28 2011-04-20 武汉远大制药集团有限公司 5,6-二甲基呫吨酮-4-乙酸的制备方法及由此方法制备的衍生物和药物制剂
CN101914084B (zh) * 2010-07-30 2012-10-17 中国人民解放军第二军医大学 双苯吡喃酮氮杂环衍生物及其制备方法与应用
CN105906602B (zh) * 2011-05-16 2018-07-10 杭州民生药物研究院有限公司 2-(5,6-二甲基呫吨酮-4-基)-乙酸衍生物的制备方法
JP7096817B2 (ja) 2016-11-04 2022-07-06 オークランド ユニサービシーズ リミティド 三環式複素環式誘導体及びその使用
CN106977489B (zh) * 2017-04-20 2019-05-31 清华大学 一种制备多取代占吨酮类衍生物的方法

Also Published As

Publication number Publication date
ES2061518T3 (es) 1994-12-16
JP2672101B2 (ja) 1997-11-05
EP0278176A2 (en) 1988-08-17
JPS63295570A (ja) 1988-12-01
EP0278176B1 (en) 1994-03-09
ATE102616T1 (de) 1994-03-15
EP0278176A3 (en) 1990-03-28
DE3789299T2 (de) 1994-08-04
DE3789299D1 (de) 1994-04-14

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20071221