HK1000541A1 - Benzene derivates, their preparation and pharmaceutical compositions containing them - Google Patents

Benzene derivates, their preparation and pharmaceutical compositions containing them Download PDF

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Publication number
HK1000541A1
HK1000541A1 HK97102146A HK97102146A HK1000541A1 HK 1000541 A1 HK1000541 A1 HK 1000541A1 HK 97102146 A HK97102146 A HK 97102146A HK 97102146 A HK97102146 A HK 97102146A HK 1000541 A1 HK1000541 A1 HK 1000541A1
Authority
HK
Hong Kong
Prior art keywords
compound
group
formula
cyclohexyl
prepare
Prior art date
Application number
HK97102146A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1000541B (en
Inventor
Breliere Jean-Claude
Casellas Pierre
Lavastre Serge
Paul Raymond
Original Assignee
赛诺菲 安万特
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 赛诺菲 安万特 filed Critical 赛诺菲 安万特
Publication of HK1000541A1 publication Critical patent/HK1000541A1/xx
Publication of HK1000541B publication Critical patent/HK1000541B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/38—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK97102146.3A 1988-12-30 1997-11-10 Benzene derivates, their preparation and pharmaceutical compositions containing them HK1000541B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8817538A FR2641276B1 (fr) 1988-12-30 1988-12-30 Derives du benzene, leur preparation et les compositions pharmaceutiques en contenant
FR8817538 1988-12-30

Publications (2)

Publication Number Publication Date
HK1000541A1 true HK1000541A1 (en) 1998-04-03
HK1000541B HK1000541B (en) 1998-04-03

Family

ID=

Also Published As

Publication number Publication date
DK674589A (da) 1990-07-01
CA2006896A1 (en) 1990-06-30
CZ419291A3 (en) 1993-05-12
FI98811C (fi) 1997-08-25
DK674589D0 (da) 1989-12-29
IL92889A0 (en) 1990-09-17
AU4737989A (en) 1990-07-05
NO895220L (no) 1990-07-02
US5354781A (en) 1994-10-11
EP0376850A1 (fr) 1990-07-04
IE894209L (en) 1990-06-30
JP2588977B2 (ja) 1997-03-12
HU211155A9 (en) 1995-10-30
AU618439B2 (en) 1991-12-19
AR247548A1 (es) 1995-01-31
US5449693A (en) 1995-09-12
DK174505B1 (da) 2003-04-28
KR900009580A (ko) 1990-07-04
ES2055138T3 (es) 1994-08-16
FR2641276B1 (fr) 1991-07-12
NO171847C (no) 1993-05-12
CA2006896C (en) 1998-06-02
EP0376850B1 (fr) 1993-03-03
DE68905171T2 (de) 1993-06-17
JPH032116A (ja) 1991-01-08
KR0178366B1 (ko) 1999-05-15
FI896342A0 (fi) 1989-12-29
ZA899955B (en) 1990-09-26
NO171847B (no) 1993-02-01
FI98811B (fi) 1997-05-15
IL92889A (en) 1994-02-27
PT92761A (pt) 1990-06-29
IE63689B1 (en) 1995-05-31
NO895220D0 (no) 1989-12-22
DE68905171D1 (de) 1993-04-08
PT92761B (pt) 1996-01-31
FR2641276A1 (fr) 1990-07-06
GR3007357T3 (cs) 1993-07-30
NZ232010A (en) 1992-03-26

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Legal Events

Date Code Title Description
PF Patent in force
CHPA Change of a particular in the register (except of change of ownership)
PE Patent expired

Effective date: 20091227