GT201100321A - "acido trans-4-[[(5s)-5-[[[3,5-bis (trifluorometil)fenil]metil](2-metil-2h-tetrazol- -5-il)amino]-2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il] metil] -ciclohexan carboxilico" - Google Patents
"acido trans-4-[[(5s)-5-[[[3,5-bis (trifluorometil)fenil]metil](2-metil-2h-tetrazol- -5-il)amino]-2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il] metil] -ciclohexan carboxilico"Info
- Publication number
- GT201100321A GT201100321A GT201100321A GT201100321A GT201100321A GT 201100321 A GT201100321 A GT 201100321A GT 201100321 A GT201100321 A GT 201100321A GT 201100321 A GT201100321 A GT 201100321A GT 201100321 A GT201100321 A GT 201100321A
- Authority
- GT
- Guatemala
- Prior art keywords
- methyl
- trifluorometil
- benzazepin
- tetrazol
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22170809P | 2009-06-30 | 2009-06-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT201100321A true GT201100321A (es) | 2012-11-15 |
Family
ID=42352717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT201100321A GT201100321A (es) | 2009-06-30 | 2011-12-13 | "acido trans-4-[[(5s)-5-[[[3,5-bis (trifluorometil)fenil]metil](2-metil-2h-tetrazol- -5-il)amino]-2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il] metil] -ciclohexan carboxilico" |
Country Status (37)
Country | Link |
---|---|
US (2) | US8329688B2 (zh) |
EP (1) | EP2448933B1 (zh) |
JP (1) | JP5689875B2 (zh) |
KR (1) | KR101404893B1 (zh) |
CN (1) | CN102639528B (zh) |
AR (1) | AR077208A1 (zh) |
AU (1) | AU2010266537B2 (zh) |
BR (1) | BRPI1011931A2 (zh) |
CA (1) | CA2764425C (zh) |
CL (1) | CL2011003263A1 (zh) |
CO (1) | CO6480934A2 (zh) |
CR (1) | CR20110669A (zh) |
DK (1) | DK2448933T3 (zh) |
DO (1) | DOP2011000405A (zh) |
EA (1) | EA020600B1 (zh) |
EC (1) | ECSP11011551A (zh) |
ES (1) | ES2435293T3 (zh) |
GT (1) | GT201100321A (zh) |
HR (1) | HRP20130950T1 (zh) |
IL (1) | IL216655A (zh) |
JO (1) | JO2867B1 (zh) |
MA (1) | MA33385B1 (zh) |
ME (1) | ME01606B (zh) |
MX (1) | MX2011014024A (zh) |
MY (1) | MY157121A (zh) |
NZ (1) | NZ596820A (zh) |
PE (1) | PE20120538A1 (zh) |
PL (1) | PL2448933T3 (zh) |
PT (1) | PT2448933E (zh) |
RS (1) | RS52988B (zh) |
SG (1) | SG177413A1 (zh) |
SI (1) | SI2448933T1 (zh) |
TN (1) | TN2011000638A1 (zh) |
TW (1) | TWI450896B (zh) |
UA (1) | UA109409C2 (zh) |
WO (1) | WO2011002696A1 (zh) |
ZA (1) | ZA201108707B (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20070041452A (ko) * | 2004-06-24 | 2007-04-18 | 일라이 릴리 앤드 캄파니 | 이상지혈증 치료를 위한 화합물 및 방법 |
AR077208A1 (es) * | 2009-06-30 | 2011-08-10 | Lilly Co Eli | Derivados del acido trans-4-[[(5s)-5-[[[3,5-bis(trifluorometil) fenil] metil] (2-metil-2h-tetrazol-5-il) amino) -2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il) metil)-ciclohexancarboxilico y sus formas cristalinas, composiciones farmaceuticas que los comprenden, su uso para preparar un medicam |
ES2683350T3 (es) * | 2011-07-08 | 2018-09-26 | Novartis Ag | Método para tratar la aterosclerosis en sujetos con alto nivel de triglicéridos |
CN103958501B (zh) * | 2012-07-16 | 2016-08-17 | 上海恒瑞医药有限公司 | 苯并七元杂环类衍生物、其制备方法及其在医药上的应用 |
DK2943474T3 (en) | 2013-01-31 | 2017-08-21 | Chong Kun Dang Pharmaceutical Corp | BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXE DERIVATE COMPOUNDS AS CETP INHIBITORS |
CN105017085B (zh) * | 2014-04-28 | 2018-06-29 | 中国科学院上海药物研究所 | 一类kcnq钾通道激动剂、其制备方法和用途 |
RU2703192C2 (ru) | 2014-07-30 | 2019-10-15 | Ф. Хоффманн-Ля Рош Аг | Генетические маркеры для прогнозирования ответа на терапию поднимающими уровень hdl или имитирующими hdl агентами |
TWI691331B (zh) | 2014-09-26 | 2020-04-21 | 日商興和股份有限公司 | 脂質異常症治療劑 |
CN108456213B (zh) * | 2017-02-22 | 2021-01-15 | 浙江九洲药业股份有限公司 | 一种3-氟-4-羟基环己烷羧酸酯的制备方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4948639B1 (zh) | 1970-12-15 | 1974-12-23 | ||
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
GT199900147A (es) | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
HN2000000203A (es) | 1999-11-30 | 2001-06-13 | Pfizer Prod Inc | Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas. |
CO5271716A1 (es) | 1999-11-30 | 2003-04-30 | Pfizer Prod Inc | Cristales de 4- carboxamino 1,2,3,4-tetrahidroquinolina 2- sustituida |
CZ20032898A3 (cs) * | 2001-04-30 | 2004-07-14 | Pfizer Products Inc. | Způsob výroby inhibitorů CETP |
EP1533292B1 (en) * | 2002-08-30 | 2007-02-14 | Japan Tobacco Inc. | Dibenzylamine compound and medicinal use thereof |
KR20050055747A (ko) * | 2002-10-04 | 2005-06-13 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 염증 질환 치료용의 pgd2 수용체 길항제 |
JP2006523218A (ja) * | 2003-03-04 | 2006-10-12 | 高砂香料工業株式会社 | 光学活性アミン類の製造方法 |
US20040204450A1 (en) * | 2003-03-28 | 2004-10-14 | Pfizer Inc | Quinoline and quinoxaline compounds |
PL1670768T3 (pl) | 2003-10-08 | 2010-01-29 | Lilly Co Eli | Związki i sposoby leczenia dyslipidemii |
ES2308477T3 (es) | 2004-03-26 | 2008-12-01 | Eli Lilly And Company | Compuestos para el tratamiento de la dislipidemia. |
CN1972927A (zh) * | 2004-06-24 | 2007-05-30 | 伊莱利利公司 | 用于治疗血脂障碍的化合物和方法 |
KR20070041452A (ko) * | 2004-06-24 | 2007-04-18 | 일라이 릴리 앤드 캄파니 | 이상지혈증 치료를 위한 화합물 및 방법 |
US7700774B2 (en) * | 2004-12-20 | 2010-04-20 | Dr. Reddy's Laboratories Ltd. | Heterocyclic compounds and their pharmaceutical compositions |
AR077208A1 (es) * | 2009-06-30 | 2011-08-10 | Lilly Co Eli | Derivados del acido trans-4-[[(5s)-5-[[[3,5-bis(trifluorometil) fenil] metil] (2-metil-2h-tetrazol-5-il) amino) -2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il) metil)-ciclohexancarboxilico y sus formas cristalinas, composiciones farmaceuticas que los comprenden, su uso para preparar un medicam |
-
2010
- 2010-06-23 AR ARP100102219A patent/AR077208A1/es unknown
- 2010-06-23 TW TW099120507A patent/TWI450896B/zh not_active IP Right Cessation
- 2010-06-24 JO JO2010211A patent/JO2867B1/en active
- 2010-06-28 JP JP2012517814A patent/JP5689875B2/ja not_active Expired - Fee Related
- 2010-06-28 US US12/824,355 patent/US8329688B2/en not_active Expired - Fee Related
- 2010-06-28 MY MYPI2011006319A patent/MY157121A/en unknown
- 2010-06-28 ES ES10728558T patent/ES2435293T3/es active Active
- 2010-06-28 PE PE2011002156A patent/PE20120538A1/es not_active Application Discontinuation
- 2010-06-28 PL PL10728558T patent/PL2448933T3/pl unknown
- 2010-06-28 UA UAA201115555A patent/UA109409C2/ru unknown
- 2010-06-28 ME MEP-2013-114A patent/ME01606B/me unknown
- 2010-06-28 NZ NZ596820A patent/NZ596820A/xx not_active IP Right Cessation
- 2010-06-28 SG SG2011097128A patent/SG177413A1/en unknown
- 2010-06-28 DK DK10728558.7T patent/DK2448933T3/da active
- 2010-06-28 EA EA201270099A patent/EA020600B1/ru not_active IP Right Cessation
- 2010-06-28 RS RS20130453A patent/RS52988B/en unknown
- 2010-06-28 SI SI201030386T patent/SI2448933T1/sl unknown
- 2010-06-28 AU AU2010266537A patent/AU2010266537B2/en not_active Ceased
- 2010-06-28 BR BRPI1011931A patent/BRPI1011931A2/pt not_active IP Right Cessation
- 2010-06-28 KR KR1020117031449A patent/KR101404893B1/ko not_active IP Right Cessation
- 2010-06-28 EP EP10728558.7A patent/EP2448933B1/en active Active
- 2010-06-28 MX MX2011014024A patent/MX2011014024A/es active IP Right Grant
- 2010-06-28 PT PT107285587T patent/PT2448933E/pt unknown
- 2010-06-28 CN CN201080029957.9A patent/CN102639528B/zh not_active Expired - Fee Related
- 2010-06-28 WO PCT/US2010/040125 patent/WO2011002696A1/en active Application Filing
- 2010-06-28 MA MA34490A patent/MA33385B1/fr unknown
- 2010-06-28 US US13/318,874 patent/US8299060B2/en not_active Expired - Fee Related
- 2010-06-28 CA CA2764425A patent/CA2764425C/en not_active Expired - Fee Related
-
2011
- 2011-11-25 ZA ZA2011/08707A patent/ZA201108707B/en unknown
- 2011-11-28 IL IL216655A patent/IL216655A/en not_active IP Right Cessation
- 2011-12-12 CR CR20110669A patent/CR20110669A/es not_active Application Discontinuation
- 2011-12-13 TN TNP2011000638A patent/TN2011000638A1/en unknown
- 2011-12-13 GT GT201100321A patent/GT201100321A/es unknown
- 2011-12-22 CO CO11177215A patent/CO6480934A2/es active IP Right Grant
- 2011-12-22 CL CL2011003263A patent/CL2011003263A1/es unknown
- 2011-12-23 EC EC2011011551A patent/ECSP11011551A/es unknown
- 2011-12-26 DO DO2011000405A patent/DOP2011000405A/es unknown
-
2013
- 2013-10-07 HR HRP20130950AT patent/HRP20130950T1/hr unknown
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