GT200200075A - Nuevas arilsulfonamidas como agentes antivirales - Google Patents

Nuevas arilsulfonamidas como agentes antivirales

Info

Publication number
GT200200075A
GT200200075A GT200200075A GT200200075A GT200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A
Authority
GT
Guatemala
Prior art keywords
hcmv
patients
new
arilsulphonamids
antiviral agents
Prior art date
Application number
GT200200075A
Other languages
English (en)
Inventor
Tobias Wunberg
Wolfang Bender
Peter Eckenberg
Sabine Hallenberger
Kerstin Henninger
Jorg Keldenich
Armin Kern
Siegfried Raddatz
Jurgen Reefschlager
Gunter Schmidt
Holger Zimmermann
Franz Zumpe
Martin Radtke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200200075A publication Critical patent/GT200200075A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVAS ARILSULFONAMIDAS DE FORMULA GENERAL (I) EN DONDE X,A,R1,R2,R3,R4, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS MUESTRAN UNA ACTIVIDAD ANTIVIRAL FRENTE A REPRESENTANTES DEL GRUPO DE HERPES VIRIDAE, ESPECIALMENTE FRENTE AL CITOMEGALOVIRUS HUMANO (HCMV) POR LO QUE SON UTILES EN LA PREVENCION Y ESTADOS INFECCIOSOS CAUSADOS POR HCMV EN PACIENTES CON SIDA, EN PACIENTES DE TRANSPLANTE DE MEDULA OSEA Y ORGANOS, EN RECIEN NACIDOS Y NIÑOS PEQUEÑOS, EN PACIENTES INMUNOSUPRIMIDOS POR CANCER, EN EMBARAZADAS POR INFECCION AGUDA CAUSADA POR HCMV.
GT200200075A 2001-04-19 2002-04-18 Nuevas arilsulfonamidas como agentes antivirales GT200200075A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19

Publications (1)

Publication Number Publication Date
GT200200075A true GT200200075A (es) 2002-12-24

Family

ID=7681939

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200200075A GT200200075A (es) 2001-04-19 2002-04-18 Nuevas arilsulfonamidas como agentes antivirales

Country Status (9)

Country Link
KR (1) KR20030088509A (es)
AR (1) AR034309A1 (es)
CO (1) CO5540388A2 (es)
DE (1) DE10148598A1 (es)
EC (1) ECSP034813A (es)
GT (1) GT200200075A (es)
PE (1) PE20021061A1 (es)
SV (1) SV2003000995A (es)
ZA (1) ZA200307892B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482366B2 (en) * 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
CA2494164A1 (en) * 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
US7144876B2 (en) * 2002-12-18 2006-12-05 Cytovia, Inc. 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
DE10300109A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Methode zur Inhibition der Replikation von Herpesviren
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
WO2007027230A2 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (es) 2006-12-30 2008-07-31 Abbott Gmbh & Amp Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
US8703774B2 (en) 2007-12-07 2014-04-22 AbbVie Deutschland GmbH & Co. KG Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
EP2231643B1 (de) 2007-12-07 2012-10-31 Abbott GmbH & Co. KG Amidomethyl-substitutierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen
MX2010006204A (es) 2007-12-07 2011-03-16 Abbott Gmbh & Co Kg Derivados de oxindol 5,6-disubstituidos y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.
RU2484090C2 (ru) 2007-12-07 2013-06-10 Эбботт Гмбх Унд Ко.Кг 5-галогензамещенные производные оксиндола и их применение для лечения вазопрессинзависимых заболеваний
EP2435080A2 (en) 2009-05-29 2012-04-04 Abbott Laboratories Pharmaceutical compositions for the treatment of pain

Also Published As

Publication number Publication date
PE20021061A1 (es) 2002-12-12
DE10148598A1 (de) 2002-10-24
AR034309A1 (es) 2004-02-18
ZA200307892B (en) 2004-10-11
KR20030088509A (ko) 2003-11-19
CO5540388A2 (es) 2005-07-29
SV2003000995A (es) 2003-03-18
ECSP034813A (es) 2003-12-01

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