GT200200075A - NEW ARILSULPHONAMIDS AS ANTIVIRAL AGENTS - Google Patents
NEW ARILSULPHONAMIDS AS ANTIVIRAL AGENTSInfo
- Publication number
- GT200200075A GT200200075A GT200200075A GT200200075A GT200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A GT 200200075 A GT200200075 A GT 200200075A
- Authority
- GT
- Guatemala
- Prior art keywords
- hcmv
- patients
- new
- arilsulphonamids
- antiviral agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A NUEVAS ARILSULFONAMIDAS DE FORMULA GENERAL (I) EN DONDE X,A,R1,R2,R3,R4, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS MUESTRAN UNA ACTIVIDAD ANTIVIRAL FRENTE A REPRESENTANTES DEL GRUPO DE HERPES VIRIDAE, ESPECIALMENTE FRENTE AL CITOMEGALOVIRUS HUMANO (HCMV) POR LO QUE SON UTILES EN LA PREVENCION Y ESTADOS INFECCIOSOS CAUSADOS POR HCMV EN PACIENTES CON SIDA, EN PACIENTES DE TRANSPLANTE DE MEDULA OSEA Y ORGANOS, EN RECIEN NACIDOS Y NIÑOS PEQUEÑOS, EN PACIENTES INMUNOSUPRIMIDOS POR CANCER, EN EMBARAZADAS POR INFECCION AGUDA CAUSADA POR HCMV.THE PRESENT INVENTION REFERS TO NEW ARILSULFONAMIDS OF GENERAL FORMULA (I) WHERE X, A, R1, R2, R3, R4, ARE FUNCTIONAL GROUPS DESCRIBED IN THE RECORD. THESE COMPOUNDS SHOW AN ANTIVIRAL ACTIVITY AGAINST REPRESENTATIVES OF THE HERPES VIRIDAE GROUP, ESPECIALLY AGAINST THE HUMAN CITOMEGALOVIRUS (HCMV), SO THAT THEY ARE USEFUL IN THE PREVENTION AND INFECTIVE STATES CAUSED BY HCMV IN PATIENTS WITH AIDS, IN PATIENTS ORGANS, IN NEWLY BORN AND SMALL CHILDREN, IN IMMUNE SUPPRESSED PATIENTS BY CANCER, IN PREGNANT BY ACUTE INFECTION CAUSED BY HCMV.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10119137 | 2001-04-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200200075A true GT200200075A (en) | 2002-12-24 |
Family
ID=7681939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200200075A GT200200075A (en) | 2001-04-19 | 2002-04-18 | NEW ARILSULPHONAMIDS AS ANTIVIRAL AGENTS |
Country Status (9)
Country | Link |
---|---|
KR (1) | KR20030088509A (en) |
AR (1) | AR034309A1 (en) |
CO (1) | CO5540388A2 (en) |
DE (1) | DE10148598A1 (en) |
EC (1) | ECSP034813A (en) |
GT (1) | GT200200075A (en) |
PE (1) | PE20021061A1 (en) |
SV (1) | SV2003000995A (en) |
ZA (1) | ZA200307892B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7482366B2 (en) * | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
CA2494164A1 (en) | 2002-08-23 | 2004-03-04 | Rigel Pharmaceuticals, Inc. | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
WO2004058253A1 (en) * | 2002-12-18 | 2004-07-15 | Cytovia, Inc. | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof |
DE10300109A1 (en) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Method for inhibiting replication of herpes viruses |
US7326790B2 (en) | 2003-05-02 | 2008-02-05 | Rigel Pharmaceuticals, Inc. | Diphenylisoxazole compounds and hydro isomers thereof |
US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
WO2005049065A2 (en) | 2003-11-19 | 2005-06-02 | Rigel Pharmaceuticals, Inc. | Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections |
US7514434B2 (en) | 2004-02-23 | 2009-04-07 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof |
CN101203498A (en) | 2005-05-02 | 2008-06-18 | 里格尔药品股份有限公司 | Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses |
US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
UY30846A1 (en) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | OXINDOL DERIVATIVES REPLACED, MEDICINES THAT UNDERSTAND AND USE THEMSELVES |
US20080255203A1 (en) * | 2007-04-12 | 2008-10-16 | Abbott Laboratories | Heterocyclic compounds and their methods of use |
CA2707671C (en) | 2007-12-07 | 2016-02-02 | Abbott Gmbh & Co. Kg | 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressine-dependent diseases |
BRPI0820668A2 (en) | 2007-12-07 | 2017-08-22 | Abbott Gmbh & Co Kg | 5-HALOGEN SUBSTITUTED OXINDOL DERIVATIVES AND THEIR USE TO TREAT VASOPRESSIN DEPENDENT DISEASES |
WO2010009775A1 (en) | 2007-12-07 | 2010-01-28 | Abbott Gmbh & Co. Kg | Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases |
MX2010006202A (en) | 2007-12-07 | 2011-03-04 | Abbott Gmbh & Co Kg | Amidomethyl-substituted oxindole derivatives and the use thereof for the treatment of vasopressin-dependent illnesses. |
WO2010138600A2 (en) | 2009-05-29 | 2010-12-02 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
-
2001
- 2001-10-02 DE DE10148598A patent/DE10148598A1/en not_active Withdrawn
-
2002
- 2002-04-08 KR KR10-2003-7013617A patent/KR20030088509A/en not_active Application Discontinuation
- 2002-04-17 AR ARP020101392A patent/AR034309A1/en unknown
- 2002-04-18 SV SV2002000995A patent/SV2003000995A/en not_active Application Discontinuation
- 2002-04-18 PE PE2002000323A patent/PE20021061A1/en not_active Application Discontinuation
- 2002-04-18 GT GT200200075A patent/GT200200075A/en unknown
-
2003
- 2003-10-09 ZA ZA200307892A patent/ZA200307892B/en unknown
- 2003-10-17 EC EC2003004813A patent/ECSP034813A/en unknown
- 2003-11-19 CO CO03102172A patent/CO5540388A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA200307892B (en) | 2004-10-11 |
KR20030088509A (en) | 2003-11-19 |
DE10148598A1 (en) | 2002-10-24 |
AR034309A1 (en) | 2004-02-18 |
CO5540388A2 (en) | 2005-07-29 |
PE20021061A1 (en) | 2002-12-12 |
ECSP034813A (en) | 2003-12-01 |
SV2003000995A (en) | 2003-03-18 |
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