ES2061770T3 - Antibioticos tan-1057. - Google Patents

Antibioticos tan-1057.

Info

Publication number
ES2061770T3
ES2061770T3 ES89107527T ES89107527T ES2061770T3 ES 2061770 T3 ES2061770 T3 ES 2061770T3 ES 89107527 T ES89107527 T ES 89107527T ES 89107527 T ES89107527 T ES 89107527T ES 2061770 T3 ES2061770 T3 ES 2061770T3
Authority
ES
Spain
Prior art keywords
hydrogen
tan
microorganisms
antibiotics
flexibacter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89107527T
Other languages
English (en)
Inventor
Hideo Ono
Yasunori Funabashi
Setsuo Harada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ES2061770T3 publication Critical patent/ES2061770T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

NUEVOS ANTIBIOTICOS TAN - 1057 REPRESENTADOS POR LA FORMULA (I), DONDE LA CONFIGURACION ABSOLUTA EN (A) ES R O S, CADA R1 Y R3 ES UN PUNTO DE ENLACE O HIDROGENO, Y R2 ES UN PUNTO DE ENLACE, SE PREVEE QUE CUANDO R2 ENLAZA CON R1 O R3 EL OTRO ES HIDROGENO, CUANDO SE PRODUCE POR MICROORGANISMOS QUE PERTENECEN AL GENERO FLEXIBACTER. TAN - 1057 INHIBEN FUERTEMENTE EL CRECIMIENTO DE MICROORGANISMOS PATOGENOS Y TUMORES MALIGNOS, POR LO QUE SON UTILES COMO AGENTES TERAPEUTICOS DE ENFERMEDADES INFECCIOSAS O AGENTES ANTITUMOR.
ES89107527T 1988-04-29 1989-04-26 Antibioticos tan-1057. Expired - Lifetime ES2061770T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10673388 1988-04-29
JP1051099A JP2873340B2 (ja) 1988-04-29 1989-03-02 抗生物質ｔａｎ―１０５７，その製造法および用途

Publications (1)

Publication Number Publication Date
ES2061770T3 true ES2061770T3 (es) 1994-12-16

Family

ID=26391630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89107527T Expired - Lifetime ES2061770T3 (es) 1988-04-29 1989-04-26 Antibioticos tan-1057.

Country Status (7)

Country Link
US (1) US4971965A (es)
EP (1) EP0339596B1 (es)
JP (1) JP2873340B2 (es)
KR (1) KR970009293B1 (es)
CA (1) CA1337802C (es)
DE (1) DE68914021T2 (es)
ES (1) ES2061770T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9115811D0 (en) * 1991-07-22 1991-09-04 Fujisawa Pharmaceutical Co Fr901451 substance,process for preparation thereof and use thereof
CA2297055A1 (en) * 1997-08-07 1999-02-18 Research Corporation Technologies, Inc. Antibiotic for methicillin resistant bacteria
AU736951C (en) 1998-03-19 2003-02-20 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
DE19838998A1 (de) * 1998-08-27 2000-03-09 Bayer Ag Neue Naturstoffderivate
EP1113008A1 (en) * 1999-12-29 2001-07-04 Pfizer Products Inc. 4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives useful as antibacterial and antiprotozoal agents
CA2635354C (en) * 2005-12-29 2012-07-10 Immupharma France Sa Compositions and methods for the inhibition of phospholipase a2
CA2635359A1 (en) * 2005-12-29 2007-07-05 Immupharma France Sa Compositions and methods for synthesizing heterocyclic therapeutic compounds
CN102712657A (zh) 2009-10-16 2012-10-03 Rib-X制药公司 抗微生物化合物和其制备和使用方法
CA2777741A1 (en) 2009-10-16 2011-04-21 Rib-X Pharmaceuticals, Inc. Antimicrobial compounds and methods of making and using the same
MX2012004340A (es) 2009-10-16 2012-11-23 Rib X Pharmaceuticals Inc Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.
JP6042330B2 (ja) 2010-07-09 2016-12-14 ビーエイチヴィ ファーマ、インコーポレイテッド レモグリフロジンを含めた半減期が短い医薬品のための組合せ即時／遅延放出送達システム
PT2697229T (pt) 2011-04-15 2018-04-13 Melinta Therapeutics Inc Compostos antimicrobianos e seus métodos de fabrico e de utilização
JP2016529325A (ja) 2013-09-09 2016-09-23 メリンタ セラピューティクス，インコーポレイテッド 抗微生物化合物ならびにそれの製造方法および使用方法
JP2016536338A (ja) 2013-09-09 2016-11-24 メリンタ セラピューティクス，インコーポレイテッド 抗微生物化合物ならびにそれの製造方法および使用方法
CA2979342A1 (en) 2015-03-11 2016-09-15 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
CA3023317A1 (en) 2016-05-06 2017-11-09 Melinta Therapeutics, Inc. Antimicrobials and methods of making and using same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440765A (en) * 1979-07-23 1984-04-03 William H. Rorer, Inc. Amidinoureas
US4258045A (en) * 1979-11-30 1981-03-24 Merck & Co., Inc. Inhibitor of dihydrofolate reductase
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
DK404982A (da) * 1981-09-11 1983-03-12 Nyegaard & Co As Fremgangsmaade til fremstilling af substituerede pyrimid-2-oner eller salte deraf
JPS5913780A (ja) * 1982-07-13 1984-01-24 Takeda Chem Ind Ltd フルオロウラシル誘導体および抗腫瘍剤
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity

Also Published As

Publication number Publication date
US4971965A (en) 1990-11-20
DE68914021D1 (de) 1994-04-28
DE68914021T2 (de) 1994-07-28
CA1337802C (en) 1995-12-26
JPH02117666A (ja) 1990-05-02
KR970009293B1 (ko) 1997-06-10
EP0339596A3 (en) 1990-11-28
EP0339596B1 (en) 1994-03-23
JP2873340B2 (ja) 1999-03-24
EP0339596A2 (en) 1989-11-02
KR900016264A (ko) 1990-11-13

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