GR862290B - Irreversible dopamine-b-hydroxylase inhibitors - Google Patents
Irreversible dopamine-b-hydroxylase inhibitorsInfo
- Publication number
- GR862290B GR862290B GR862290A GR860102290A GR862290B GR 862290 B GR862290 B GR 862290B GR 862290 A GR862290 A GR 862290A GR 860102290 A GR860102290 A GR 860102290A GR 862290 B GR862290 B GR 862290B
- Authority
- GR
- Greece
- Prior art keywords
- dopamine
- irreversible
- hydroxylase inhibitors
- preparation
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/773,694 US4760089A (en) | 1985-09-09 | 1985-09-09 | Irreversible dopamine-β-hydroxylase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR862290B true GR862290B (en) | 1987-01-02 |
Family
ID=25099026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR862290A GR862290B (en) | 1985-09-09 | 1986-09-08 | Irreversible dopamine-b-hydroxylase inhibitors |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4760089A (el) |
| EP (1) | EP0219961B1 (el) |
| JP (1) | JPS6261960A (el) |
| AT (1) | ATE41146T1 (el) |
| AU (1) | AU595232B2 (el) |
| DE (1) | DE3662265D1 (el) |
| DK (1) | DK421586A (el) |
| ES (1) | ES2001775A6 (el) |
| GR (1) | GR862290B (el) |
| PT (1) | PT83316B (el) |
| ZA (1) | ZA866808B (el) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760089A (en) * | 1985-09-09 | 1988-07-26 | Smithkline Beckman Corporation | Irreversible dopamine-β-hydroxylase inhibitors |
| MTP1031B (en) * | 1987-12-24 | 1990-10-04 | Orion Yhtymae Oy | New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters |
| US5637767A (en) * | 1995-06-07 | 1997-06-10 | Warner-Lambert Company | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid |
| EP1737809B1 (en) * | 2004-02-27 | 2013-09-18 | Amgen, Inc | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| US7465804B2 (en) * | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| US7582803B2 (en) * | 2005-09-14 | 2009-09-01 | Amgen Inc. | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders |
| WO2007106469A2 (en) * | 2006-03-14 | 2007-09-20 | Amgen Inc. | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders |
| US7687526B2 (en) * | 2006-09-07 | 2010-03-30 | Amgen Inc. | Benzo-fused compounds for use in treating metabolic disorders |
| CA2662305C (en) * | 2006-09-07 | 2012-04-17 | Amgen Inc. | Heterocyclic gpr40 modulators |
| JP2010524932A (ja) * | 2007-04-16 | 2010-07-22 | アムジエン・インコーポレーテツド | 置換ビフェニルフェノキシ−、チオフェニル−及びアミノフェニルプロパン酸ｇｐｒ４０調節物質 |
| WO2009048527A1 (en) | 2007-10-10 | 2009-04-16 | Amgen Inc. | Substituted biphenyl gpr40 modulators |
| CA2716352C (en) * | 2008-03-06 | 2013-05-28 | Amgen Inc. | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| US8748462B2 (en) * | 2008-10-15 | 2014-06-10 | Amgen Inc. | Spirocyclic GPR40 modulators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2757031C2 (de) * | 1976-12-27 | 1981-11-26 | Agency Of Industrial Science And Technology | Verfahren zur Herstellung von Aldehyden und/oder Alkoholen aus einem Toluolderivat mit Ätherbindungen |
| DE2950608A1 (de) * | 1978-12-29 | 1980-07-10 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur herstellung von 2-(3-phenoxy-phenyl)-propionsaeure |
| DE3144150A1 (de) * | 1981-04-10 | 1982-12-09 | Basf Ag, 6700 Ludwigshafen | (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel |
| US4496757A (en) * | 1981-11-05 | 1985-01-29 | Ciba-Geigy Corporation | Ultraviolet-absorbing stabilizers substituted an aliphatic hydroxyl group |
| US4760089A (en) * | 1985-09-09 | 1988-07-26 | Smithkline Beckman Corporation | Irreversible dopamine-β-hydroxylase inhibitors |
-
1985
- 1985-09-09 US US06/773,694 patent/US4760089A/en not_active Expired - Fee Related
-
1986
- 1986-09-02 AU AU62168/86A patent/AU595232B2/en not_active Ceased
- 1986-09-03 DK DK421586A patent/DK421586A/da unknown
- 1986-09-05 ES ES8601668A patent/ES2001775A6/es not_active Expired
- 1986-09-05 PT PT83316A patent/PT83316B/pt unknown
- 1986-09-08 EP EP86306923A patent/EP0219961B1/en not_active Expired
- 1986-09-08 ZA ZA866808A patent/ZA866808B/xx unknown
- 1986-09-08 GR GR862290A patent/GR862290B/el unknown
- 1986-09-08 AT AT86306923T patent/ATE41146T1/de not_active IP Right Cessation
- 1986-09-08 JP JP61212537A patent/JPS6261960A/ja active Pending
- 1986-09-08 DE DE8686306923T patent/DE3662265D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT83316A (en) | 1986-10-01 |
| PT83316B (en) | 1988-10-07 |
| ATE41146T1 (de) | 1989-03-15 |
| EP0219961B1 (en) | 1989-03-08 |
| DE3662265D1 (en) | 1989-04-13 |
| EP0219961A1 (en) | 1987-04-29 |
| AU6216886A (en) | 1987-03-12 |
| DK421586D0 (da) | 1986-09-03 |
| ZA866808B (en) | 1987-08-26 |
| DK421586A (da) | 1987-03-10 |
| JPS6261960A (ja) | 1987-03-18 |
| ES2001775A6 (es) | 1988-06-16 |
| US4760089A (en) | 1988-07-26 |
| AU595232B2 (en) | 1990-03-29 |
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