DK421586A - Irreversible dopamin-beta-hydroxylaseinhibitorer - Google Patents
Irreversible dopamin-beta-hydroxylaseinhibitorer Download PDFInfo
- Publication number
- DK421586A DK421586A DK421586A DK421586A DK421586A DK 421586 A DK421586 A DK 421586A DK 421586 A DK421586 A DK 421586A DK 421586 A DK421586 A DK 421586A DK 421586 A DK421586 A DK 421586A
- Authority
- DK
- Denmark
- Prior art keywords
- dopamine
- beta
- irreversible
- hydroxylase inhibitors
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/773,694 US4760089A (en) | 1985-09-09 | 1985-09-09 | Irreversible dopamine-β-hydroxylase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK421586D0 DK421586D0 (da) | 1986-09-03 |
| DK421586A true DK421586A (da) | 1987-03-10 |
Family
ID=25099026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK421586A DK421586A (da) | 1985-09-09 | 1986-09-03 | Irreversible dopamin-beta-hydroxylaseinhibitorer |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4760089A (da) |
| EP (1) | EP0219961B1 (da) |
| JP (1) | JPS6261960A (da) |
| AT (1) | ATE41146T1 (da) |
| AU (1) | AU595232B2 (da) |
| DE (1) | DE3662265D1 (da) |
| DK (1) | DK421586A (da) |
| ES (1) | ES2001775A6 (da) |
| GR (1) | GR862290B (da) |
| PT (1) | PT83316B (da) |
| ZA (1) | ZA866808B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760089A (en) * | 1985-09-09 | 1988-07-26 | Smithkline Beckman Corporation | Irreversible dopamine-β-hydroxylase inhibitors |
| MTP1031B (en) * | 1987-12-24 | 1990-10-04 | Orion Yhtymae Oy | New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters |
| US5637767A (en) * | 1995-06-07 | 1997-06-10 | Warner-Lambert Company | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid |
| CA2558585C (en) * | 2004-02-27 | 2010-10-12 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| US7465804B2 (en) * | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| US7582803B2 (en) * | 2005-09-14 | 2009-09-01 | Amgen Inc. | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders |
| MX2008011615A (es) * | 2006-03-14 | 2008-09-22 | Amgen Inc | Derivados de acidos carboxilicos biciclicos utiles para tratar trastornos metabolicos. |
| WO2008030618A1 (en) * | 2006-09-07 | 2008-03-13 | Amgen Inc. | Benzo-fused compounds for use in treating metabolic disorders |
| EP2064193A1 (en) * | 2006-09-07 | 2009-06-03 | Amgen, Inc | Heterocyclic gpr40 modulators |
| US7572934B2 (en) * | 2007-04-16 | 2009-08-11 | Amgen Inc. | Substituted biphenyl GPR40 modulators |
| BRPI0818253A2 (pt) | 2007-10-10 | 2015-04-07 | Amgen Inc | Moduladores de gpr40 bifenil substituídos |
| JP2011515341A (ja) * | 2008-03-06 | 2011-05-19 | アムジエン・インコーポレーテツド | 代謝障害の治療に有用な立体配座的に制限されたカルボン酸誘導体 |
| CA2739888C (en) * | 2008-10-15 | 2013-11-19 | Amgen Inc. | Spirocyclic gpr40 modulators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2757031C2 (de) * | 1976-12-27 | 1981-11-26 | Agency Of Industrial Science And Technology | Verfahren zur Herstellung von Aldehyden und/oder Alkoholen aus einem Toluolderivat mit Ätherbindungen |
| DE2950608A1 (de) * | 1978-12-29 | 1980-07-10 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur herstellung von 2-(3-phenoxy-phenyl)-propionsaeure |
| DE3144150A1 (de) * | 1981-04-10 | 1982-12-09 | Basf Ag, 6700 Ludwigshafen | (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel |
| US4496757A (en) * | 1981-11-05 | 1985-01-29 | Ciba-Geigy Corporation | Ultraviolet-absorbing stabilizers substituted an aliphatic hydroxyl group |
| US4760089A (en) * | 1985-09-09 | 1988-07-26 | Smithkline Beckman Corporation | Irreversible dopamine-β-hydroxylase inhibitors |
-
1985
- 1985-09-09 US US06/773,694 patent/US4760089A/en not_active Expired - Fee Related
-
1986
- 1986-09-02 AU AU62168/86A patent/AU595232B2/en not_active Ceased
- 1986-09-03 DK DK421586A patent/DK421586A/da unknown
- 1986-09-05 ES ES8601668A patent/ES2001775A6/es not_active Expired
- 1986-09-05 PT PT83316A patent/PT83316B/pt unknown
- 1986-09-08 GR GR862290A patent/GR862290B/el unknown
- 1986-09-08 EP EP86306923A patent/EP0219961B1/en not_active Expired
- 1986-09-08 JP JP61212537A patent/JPS6261960A/ja active Pending
- 1986-09-08 DE DE8686306923T patent/DE3662265D1/de not_active Expired
- 1986-09-08 ZA ZA866808A patent/ZA866808B/xx unknown
- 1986-09-08 AT AT86306923T patent/ATE41146T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6261960A (ja) | 1987-03-18 |
| AU595232B2 (en) | 1990-03-29 |
| DK421586D0 (da) | 1986-09-03 |
| EP0219961B1 (en) | 1989-03-08 |
| PT83316B (en) | 1988-10-07 |
| ZA866808B (en) | 1987-08-26 |
| DE3662265D1 (en) | 1989-04-13 |
| ES2001775A6 (es) | 1988-06-16 |
| EP0219961A1 (en) | 1987-04-29 |
| GR862290B (en) | 1987-01-02 |
| ATE41146T1 (de) | 1989-03-15 |
| AU6216886A (en) | 1987-03-12 |
| PT83316A (en) | 1986-10-01 |
| US4760089A (en) | 1988-07-26 |
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