GR861357B - Improved method for the isolation and purification of hepatitis b surface antigen - Google Patents

Improved method for the isolation and purification of hepatitis b surface antigen

Info

Publication number
GR861357B
GR861357B GR861357A GR860101357A GR861357B GR 861357 B GR861357 B GR 861357B GR 861357 A GR861357 A GR 861357A GR 860101357 A GR860101357 A GR 860101357A GR 861357 B GR861357 B GR 861357B
Authority
GR
Greece
Prior art keywords
hepatitis
isolation
purification
improved method
surface antigen
Prior art date
Application number
GR861357A
Other languages
Greek (el)
English (en)
Inventor
Wijnendaele Van Frans
Simonet Guy
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of GR861357B publication Critical patent/GR861357B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/826Viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Magnetic Heads (AREA)
  • Adornments (AREA)
  • Insulated Conductors (AREA)
GR861357A 1985-05-30 1986-05-26 Improved method for the isolation and purification of hepatitis b surface antigen GR861357B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/739,415 US4649192A (en) 1985-05-30 1985-05-30 Method for the isolation and purification of hepatitis B surface antigen using polysorbate

Publications (1)

Publication Number Publication Date
GR861357B true GR861357B (en) 1986-09-25

Family

ID=24972199

Family Applications (1)

Application Number Title Priority Date Filing Date
GR861357A GR861357B (en) 1985-05-30 1986-05-26 Improved method for the isolation and purification of hepatitis b surface antigen

Country Status (12)

Country Link
US (1) US4649192A (cg-RX-API-DMAC7.html)
EP (1) EP0204680B1 (cg-RX-API-DMAC7.html)
JP (1) JPS61280438A (cg-RX-API-DMAC7.html)
AT (1) ATE42679T1 (cg-RX-API-DMAC7.html)
AU (1) AU589331B2 (cg-RX-API-DMAC7.html)
CA (1) CA1259922A (cg-RX-API-DMAC7.html)
DE (1) DE3663108D1 (cg-RX-API-DMAC7.html)
DK (1) DK247586A (cg-RX-API-DMAC7.html)
ES (1) ES8706444A1 (cg-RX-API-DMAC7.html)
GR (1) GR861357B (cg-RX-API-DMAC7.html)
PT (1) PT82644B (cg-RX-API-DMAC7.html)
ZA (1) ZA863935B (cg-RX-API-DMAC7.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
JPS63501121A (ja) * 1985-08-15 1988-04-28 アムジエン 酵母細胞からb型肝炎表面抗原を抽出するための細胞溶解法および緩衝液
US4742158A (en) * 1986-04-25 1988-05-03 Merck & Co., Inc. Purification of hepatitis pre-S antigens by polymerized serum albumin affinity binding
JPH0789951B2 (ja) * 1986-06-18 1995-10-04 財団法人阪大微生物病研究会 遺伝子発現産物の精製法
RU1389060C (ru) * 1986-08-13 1993-06-30 Институт иммунологии Способ получени рекомбинатной вакцины к гепатиту В
US4683293A (en) * 1986-10-20 1987-07-28 Phillips Petroleum Company Purification of pichia produced lipophilic proteins
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
ATE91304T1 (de) * 1987-02-27 1993-07-15 Merck & Co Inc Verfahren zur herstellung des pres 1/s2/shepatitis-b-antigens aus hefe.
IL86833A0 (en) * 1987-06-22 1988-11-30 Medico Labs Peptide containing immunogenic particles
US4883865A (en) * 1987-09-30 1989-11-28 Merck & Co. Inc. Recovery of pres2+s antigen
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
US5030720A (en) * 1988-09-01 1991-07-09 Merck & Co., Inc. Pres2+S hepatitis B vaccine derived from plasma
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
EP0533492A3 (en) * 1991-09-18 1994-08-10 Amgen Inc A hepatitis b vaccine formulation incorporating a bile acid salt
KR960023066A (ko) * 1994-12-10 1996-07-18 성재갑 전에스 (s) 2 펩티드 함유 비 (b) 형 간염 표면항원의 정제 방법
UA79735C2 (uk) 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
KR100401423B1 (ko) * 2001-01-10 2003-10-17 주식회사 엘지생명과학 혼합 백신의 제조 방법
US20040057969A1 (en) * 2002-09-20 2004-03-25 Smith Mark L Compositions containing stabilized hepatitis antigen and methods of their use
CA2617362A1 (en) * 2005-08-02 2007-02-08 Novartis Vaccines And Diagnostics S.R.L. Reducing interference between oil-containing adjuvants and surfactant-containing antigens
EP2024520B1 (en) 2006-05-11 2014-03-05 Becton, Dickinson and Company Method of protein extraction from cells
US9207240B2 (en) * 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
AU2018357917B2 (en) 2017-10-30 2024-08-01 Takeda Pharmaceutical Company Limited Environmentally compatible detergents for inactivation of lipid-enveloped viruses

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2303562A1 (fr) * 1975-03-14 1976-10-08 Community Blood Council Greate Nouvelle preparation d'antigene utilisable comme vaccin
US4113712A (en) * 1976-03-08 1978-09-12 The Green Cross Corporation HBsAG Particle composed of single polypeptide subunits and the preparation procedure
US4102996A (en) * 1977-04-20 1978-07-25 Merck & Co., Inc. Method of preparing hepatitis B core antigen
US4136094A (en) * 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin
US4234564A (en) * 1977-12-19 1980-11-18 Merck & Co., Inc. Hepatitis B core antigen composition
US4315919A (en) * 1980-10-06 1982-02-16 Edward Shanbrom Depyrogenation process
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
JPH0625069B2 (ja) * 1981-01-29 1994-04-06 ブリティッシュ・テクノロジー・グループ・リミテッド B型肝炎ワクチン製造方法
GR76274B (cg-RX-API-DMAC7.html) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
JPS59101426A (ja) * 1982-11-29 1984-06-12 Green Cross Corp:The B型肝炎感染予防用ワクチンの製造方法
EP0135435A3 (en) * 1983-08-22 1987-03-25 Merck & Co. Inc. Immunogenic hbsag derived from transformed yeast
JPS60197629A (ja) * 1984-03-16 1985-10-07 Chemo Sero Therapeut Res Inst HBs抗原の精製方法

Also Published As

Publication number Publication date
JPS61280438A (ja) 1986-12-11
EP0204680B1 (fr) 1989-05-03
DK247586A (da) 1986-12-01
ES555442A0 (es) 1987-07-01
AU5790686A (en) 1986-12-04
ZA863935B (en) 1987-03-25
US4649192A (en) 1987-03-10
PT82644A (en) 1986-06-01
JPH0450294B2 (cg-RX-API-DMAC7.html) 1992-08-13
ES8706444A1 (es) 1987-07-01
DE3663108D1 (en) 1989-06-08
EP0204680A2 (fr) 1986-12-10
CA1259922A (en) 1989-09-26
AU589331B2 (en) 1989-10-05
EP0204680A3 (en) 1987-01-14
PT82644B (pt) 1988-03-03
DK247586D0 (da) 1986-05-27
ATE42679T1 (de) 1989-05-15

Similar Documents

Publication Publication Date Title
GR861357B (en) Improved method for the isolation and purification of hepatitis b surface antigen
MY102936A (en) Process for the extraction and purification of proteins from culture media producing them.
AU1093088A (en) Hepatitis b virus surface antigens and hybrid antigens containing them
AU7466887A (en) Method for modifying the surface of finely divided silica
WO1999062526A3 (en) Use of genetically engineered antibodies to cd38 to treat multiple myeloma
PT82345A (en) Process for the reduction of nitrogen oxides
EP0027262A3 (en) Purification of interferon
DE3470463D1 (en) Process for the conversion of nitrogen oxides in flue gases
AU6663990A (en) Chimeric mouse-human antibodies with specificity to hiv antigens
AU1493995A (en) Monoclonal antibody
DE3470747D1 (en) Immune interferon and method for its purification
AU1516988A (en) Method of preparing highly purified alpha-1-proteinase inhibitor
GB2143613B (en) Hydraulic buffer for elevators with air flow to remove contaminants
AU1439195A (en) Monoclonal antibodies to hepatitis e virus and methods for using same
FI823476A7 (fi) Menetelmä ja laitteisto energiakulutuksen minimoimiseksi pelkistettäessä rautaoksidia pelkistäpelkistävillä kaasuilla.
KR970061272A (ko) B형 간염 표면 항원의 정제방법
ZA945696B (en) Novel Eimeria antibodies and antigens and methods of using the same
AU530850B3 (en) Method for purifying or concentrating antigens
AT385005B (de) Verfahren zur justierung und montage von streckentrennern mit unbeschliffenem isolator und schleifkufen sowie zur durchfuehrung des verfahrens besonders geeigneter streckentrenner
SE8904092L (en) Fillet arrangement for holding glass panes in window - is made of composite material with low through passage coefficient and density
IE880667L (en) Purification of recombinant hepatitis b surface antigen
CU21511A1 (en) Procedure for the antigen purification of behepatitis surfaces