GR78733B - - Google Patents

Info

Publication number
GR78733B
GR78733B GR72936A GR830172936A GR78733B GR 78733 B GR78733 B GR 78733B GR 72936 A GR72936 A GR 72936A GR 830172936 A GR830172936 A GR 830172936A GR 78733 B GR78733 B GR 78733B
Authority
GR
Greece
Application number
GR72936A
Other languages
Greek (el)
Inventor
Michael G Goodman
William O Weigle
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/439,846 external-priority patent/US4539205A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of GR78733B publication Critical patent/GR78733B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR72936A 1982-11-09 1983-11-09 GR78733B (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/439,846 US4539205A (en) 1982-11-09 1982-11-09 Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US06/546,679 US4643992A (en) 1982-11-09 1983-11-01 Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives

Publications (1)

Publication Number Publication Date
GR78733B true GR78733B (enExample) 1984-10-02

Family

ID=27032191

Family Applications (1)

Application Number Title Priority Date Filing Date
GR72936A GR78733B (enExample) 1982-11-09 1983-11-09

Country Status (15)

Country Link
US (1) US4643992A (enExample)
EP (1) EP0112632B1 (enExample)
AU (1) AU568325B2 (enExample)
CA (1) CA1236401A (enExample)
DE (1) DE3382156D1 (enExample)
DK (1) DK167898B1 (enExample)
ES (1) ES527138A0 (enExample)
FI (1) FI87733C (enExample)
GR (1) GR78733B (enExample)
IE (1) IE56701B1 (enExample)
IL (1) IL70164A (enExample)
NO (1) NO174215C (enExample)
NZ (1) NZ206208A (enExample)
PT (1) PT77636B (enExample)
WO (1) WO1984001898A1 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476659A (en) * 1982-11-09 1995-12-19 The Scripps Research Institute Cancerous B cell treatment using substituted nucleoside derivatives
US4849411A (en) * 1982-11-09 1989-07-18 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US4900675A (en) * 1983-11-01 1990-02-13 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-β-aldoglycosidyl) derivatives
US5093318A (en) * 1983-11-01 1992-03-03 Scripps Clinic And Research Foundation Immunostimulating guanosine derivatives and their pharmaceutical compositions
US5166141A (en) * 1983-11-01 1992-11-24 Scripps Clinic And Research Foundation Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals
FR2560212B1 (fr) * 1984-02-24 1989-12-29 Unicet Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
US5011828A (en) * 1985-11-15 1991-04-30 Michael Goodman Immunostimulating guanine derivatives, compositions and methods
ZA869297B (en) * 1985-12-13 1987-11-25 Scripps Clinic Res Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl)derivatives
US6060459A (en) * 1987-10-28 2000-05-09 Pro-Neuron, Inc. Enhancing blood cell count with oxypurine nucleosides
US4880784A (en) * 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
US4902985A (en) * 1988-02-25 1990-02-20 Raytheon Company Microwave reflectiion amplifiers having increased bandwidth
GB2216416B (en) * 1988-03-11 1992-06-24 Sandoz Ltd Nucleobase source for the stimulation of the immune system
AU3578189A (en) * 1988-04-27 1989-11-24 Immunomedics Inc. Improved radiotherapy
WO1994011003A1 (en) * 1992-11-13 1994-05-26 The Scripps Research Institute Cancerous b cell treatment using substituted nucleoside derivatives
US5441942A (en) * 1994-05-27 1995-08-15 The Scripps Research Institute 2'3'-dideoxy-2',3'-didehydro-7,8-disubstituted guanosines and their immunostimulative effect
US5786359A (en) * 1994-05-27 1998-07-28 The Scripps Research Institute N9 alkyl or aralkyl derivatives of 7, 8-disubstituted guanines
US6338963B1 (en) 1994-07-25 2002-01-15 Neotherapeutics, Inc. Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US20030100520A1 (en) * 1997-01-21 2003-05-29 Philip Needleman Immunological process and constructs for increasing the hdl cholesterol concentration by dna vaccination
US6303617B1 (en) 1998-05-04 2001-10-16 Neotherapeutics, Inc. Serotonin-like 9-substituted hypoxanthine and methods of use
WO2000062803A2 (en) * 1999-04-15 2000-10-26 Board Of Regents, The University Of Texas System ppGpp AND pppGpp AS IMMUNOMODULATORY AGENTS
US6288069B1 (en) 1999-11-16 2001-09-11 Neotherapeutics, Inc. Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en) 2001-02-21 2002-06-18 Neotherapeutics, Inc. Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en) 2000-06-23 2005-02-01 Merck Eprova Ag Methods of synthesis for 9-substituted hypoxanthine derivatives
ATE499103T1 (de) 2000-07-07 2011-03-15 Spectrum Pharmaceuticals Inc Verfahren zur behandlung von arzneimittelinduzierter peripherer neuropathie und verwandten krankheitsformen
US20030138769A1 (en) * 2000-08-16 2003-07-24 Birkett Ashley J. Immunogenic HBc chimer particles having enhanced stability
US6759427B2 (en) 2001-04-20 2004-07-06 Spectrum Pharmaceuticals, Inc. Synthesis and methods of use of tetrahydroindolone analogues and derivatives
AU2002312487A1 (en) * 2001-06-15 2003-01-02 Ribapharm Nucleoside vaccine adjuvants
US20030055249A1 (en) * 2001-07-17 2003-03-20 Fick David B. Synthesis and methods of use of pyrimidine analogues and derivatives
US20030175863A1 (en) * 2001-08-15 2003-09-18 Birkett Ashley J. Influenza immunogen and vaccine
US7361352B2 (en) * 2001-08-15 2008-04-22 Acambis, Inc. Influenza immunogen and vaccine
US7321033B2 (en) * 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
US7351413B2 (en) * 2002-02-21 2008-04-01 Lorantis, Limited Stabilized HBc chimer particles as immunogens for chronic hepatitis
OA13310A (en) 2003-09-05 2007-04-13 Anadys Pharmaceuticals Inc TLR7 ligands for the treatment of hepatitis C.
DK2561872T3 (en) 2004-12-17 2014-12-08 Anadys Pharmaceuticals Inc 3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED 3H-OXAZOLO- [4,5-d] PYRIMIDIN-2-ON COMPOUNDS AND PRODRUGS THEREOF
EP1973920B1 (en) 2005-11-21 2010-07-21 Anadys Pharmaceuticals, Inc. Process for the preparation of 5-amino-3h-thiazolo [4,5-d] pyrimidin-2-one
KR101461604B1 (ko) * 2006-06-22 2014-11-18 애나디스 파마슈티칼스, 인코포레이티드 5-아미노-3-(3''-데옥시-β-Ｄ-리보퓨라노실)-티아졸로［4,5-ｄ］파이리미딘-2,7-다이온의 프로드럭
BRPI0714831A2 (pt) 2006-07-18 2013-04-02 Anadys Pharmaceuticals Inc composto, composiÇço farmacÊutica e mÉtodos de modulaÇço de atividades imuno da citoquina em paciente, de tratamento de infecÇço de vÍrus c da hepatite em paciente e de desordem relacionada com proliferaÇço em mamÍfero necessitado do mesmo
WO2009016639A2 (en) 2007-08-02 2009-02-05 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope influenza vaccines
WO2009073179A2 (en) 2007-12-03 2009-06-11 President And Fellows Of Harvard College Chlamydia antigens
KR20110091560A (ko) 2008-12-03 2011-08-11 프로테아 벡신 테크놀로지스 엘티디. 글루타밀 ｔＲＮＡ 합성효소(ＧｔＳ) 단편들
CN103497192B (zh) 2008-12-09 2015-09-23 吉里德科学公司 Toll样受体调节剂
WO2011067758A2 (en) 2009-12-02 2011-06-09 Protea Vaccine Technologies Ltd. Immunogenic fragments and multimers from streptococcus pneumoniae proteins
US9303070B2 (en) 2011-02-22 2016-04-05 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
ES2702278T3 (es) 2012-04-01 2019-02-28 Technion Res & Dev Foundation Péptidos de inductor de metaloproteinasa de matriz extracelular (emmprin) y anticuerpos de unión
CA2944768C (en) 2014-04-03 2022-08-30 Biondvax Pharmaceuticals Ltd. Compositions of multimeric-multiepitope influenza polypeptides and their production
JP6522732B2 (ja) 2014-07-11 2019-05-29 ギリアード サイエンシーズ， インコーポレイテッド Ｈｉｖを治療するためのトール様受容体の調節因子
KR20190125537A (ko) 2014-09-16 2019-11-06 길리애드 사이언시즈, 인코포레이티드 톨-유사 수용체 조정제의 고체 형태

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174077A (en) * 1967-02-18 1969-12-10 Ajinomoto Kk Process for Preparing 8-Mercaptopurine Derivatives

Also Published As

Publication number Publication date
FI842748A0 (fi) 1984-07-09
IE56701B1 (en) 1991-11-06
ES8601301A1 (es) 1985-11-01
AU568325B2 (en) 1987-12-24
AU2330284A (en) 1984-06-04
NO174215B (no) 1993-12-20
DK167898B1 (da) 1994-01-03
CA1236401A (en) 1988-05-10
NO842765L (no) 1984-07-06
US4643992A (en) 1987-02-17
NO174215C (no) 1994-03-30
FI842748L (fi) 1984-07-09
ES527138A0 (es) 1985-11-01
IL70164A0 (en) 1984-02-29
IE832605L (en) 1984-05-09
DK334884A (da) 1984-07-06
IL70164A (en) 1988-06-30
WO1984001898A1 (en) 1984-05-24
NZ206208A (en) 1987-03-31
FI87733C (fi) 1993-02-25
FI87733B (fi) 1992-11-13
EP0112632A3 (en) 1985-01-23
EP0112632A2 (en) 1984-07-04
DK334884D0 (da) 1984-07-06
PT77636A (en) 1983-12-01
EP0112632B1 (en) 1991-02-06
PT77636B (en) 1986-03-19
DE3382156D1 (de) 1991-03-14

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