GR76921B - - Google Patents

Info

Publication number
GR76921B
GR76921B GR66622A GR810166622A GR76921B GR 76921 B GR76921 B GR 76921B GR 66622 A GR66622 A GR 66622A GR 810166622 A GR810166622 A GR 810166622A GR 76921 B GR76921 B GR 76921B
Authority
GR
Greece
Application number
GR66622A
Inventor
Paul W Erhardt
Robert J Borgman
John P O' Donnell
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of GR76921B publication Critical patent/GR76921B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR66622A 1980-11-28 1981-11-26 GR76921B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/211,345 US4387103A (en) 1980-11-28 1980-11-28 Method for treatment or prophylaxis of cardiac disorders

Publications (1)

Publication Number Publication Date
GR76921B true GR76921B (el) 1984-09-04

Family

ID=22786543

Family Applications (1)

Application Number Title Priority Date Filing Date
GR66622A GR76921B (el) 1980-11-28 1981-11-26

Country Status (15)

Country Link
US (1) US4387103A (el)
EP (2) EP0053435B1 (el)
JP (1) JPS57502123A (el)
KR (1) KR880001539B1 (el)
AU (1) AU546424B2 (el)
CA (1) CA1258868A (el)
DK (1) DK164660C (el)
EG (1) EG16108A (el)
GR (1) GR76921B (el)
IL (1) IL64345A (el)
NZ (1) NZ198889A (el)
PH (1) PH18384A (el)
RO (1) RO85311A (el)
WO (1) WO1982001869A1 (el)
ZA (1) ZA817737B (el)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004088L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
DE3248835A1 (de) * 1981-06-23 1983-06-30 American Hospital Supply Corp Zusammensetzungen fuer die behandlung von glaukom
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4582855A (en) * 1981-11-12 1986-04-15 American Hospital Supply Corporation Aromatic and esters of hydroxypropylamines
US4508725A (en) * 1982-12-22 1985-04-02 American Hospital Supply Corporation Esters of 3-(3-substituted-amino-2-hydroxypropoxy)-4-substituted-1,2,5-thiadiazole derivatives
US4556668A (en) * 1983-07-15 1985-12-03 American Hospital Supply Corporation Ethylenediamine derivatives of aryloxypropanolamine aryl esters having various medicinal properties
EP0174956B1 (en) * 1984-03-14 1990-08-16 BODOR, Nicholas S. SOFT $g(b)-ADRENERGIC BLOCKING AGENTS
US5202347A (en) * 1984-03-14 1993-04-13 Bodor Nicholas S Soft β-adrenergic blocking agents
US5334601A (en) * 1984-03-14 1994-08-02 Bodor Nicholas S Soft β-adrenergic blocking agents
US5135926A (en) * 1984-03-14 1992-08-04 Bodor Nicholas S Soft β-adrenergic blocking agents
US4579867A (en) * 1984-04-09 1986-04-01 American Hospital Supply Corporation Stable pharmaceutical compositions of short-acting β-adrenergic receptor blocking agents
WO1985004580A1 (en) * 1984-04-09 1985-10-24 American Hospital Supply Corporation Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders
EP0279844A4 (en) * 1986-09-02 1990-06-05 Du Pont AFLÖSUNG VON DE dl-METHYL-3-4- (2-HYDROXY-3-ISOPROPYLAMINO) PROPOXY] PHENYLPROPIONAT (DL-ESMOLOL)].
ES2065291B1 (es) * 1993-07-30 1995-10-01 Prodesfarma Sa "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"
US5536749A (en) * 1994-10-13 1996-07-16 Sl Pharmaceuticals, Inc. Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents
US6197817B1 (en) * 1999-01-22 2001-03-06 Selectus Pharmaceuticals, Inc. Phenylpropionic acids and esters: compounds and methods for inducing beta-blockade for the treatment of cardiac disorders
US6756047B2 (en) * 2000-05-12 2004-06-29 The University Of Toledo Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
US7049326B2 (en) 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects
US6750238B1 (en) 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs
ES2265437T3 (es) * 2000-07-27 2007-02-16 Pharmacia Corporation Terapia de combinacion antagonista epoxi-esteroidal de aldosterona y antagonista beta-adrenergico para tratamiento de la insuficiencia cardiaca congestiva.
EP1417962A1 (de) 2002-11-06 2004-05-12 AOP Orphan Pharmaceuticals AG Verfahren zur Herstellung eines Arzneimittels enthaltend Esmolol
JP4816083B2 (ja) * 2003-08-08 2011-11-16 小野薬品工業株式会社 短時間型β遮断薬を有効成分とする心拍数減少剤
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
KR20100127845A (ko) * 2008-03-24 2010-12-06 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 심근 질환의 영상-유도된 치료: 조성물, 제조 및 적용

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637852A (en) * 1963-08-26 1972-01-25 Boehringer Sohn Ingelheim 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
DE1643262C3 (de) * 1967-12-13 1975-06-26 C.H. Boehringer Sohn, 6507 Ingelheim i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
ES361530A1 (es) * 1967-12-18 1970-11-01 Boehringer Sohn Ingelheim Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi 3-sec - alcohilamino propanos racemicos u opticamente activos.
US3740444A (en) * 1968-01-25 1973-06-19 Boehringer Sohn Ingelheim Therapeutic compositions and method
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
DE1937477C3 (de) * 1969-07-23 1980-04-10 C.H. Boehringer Sohn, 6507 Ingelheim I -Phenoxy-2-hydroxy-3-(l -methylcycloalkylamino)-propane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US3705907A (en) * 1970-02-19 1972-12-12 Sandoz Ltd 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
DE2130393C3 (de) * 1970-06-22 1981-02-26 E.R. Squibb & Sons Inc., New York, N.Y. (V.St.A.) 6,7-Dihydroxy -5,6,7,8-tetrahydronaphthyloxyaminopropanole und ihre Salze mit Säuren sowie ihre Verwendung bei der Bekämpfung von Herzerkrankungen
FR2192812A1 (en) * 1972-07-20 1974-02-15 Centre Etd Ind Pharma 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
US3857873A (en) * 1974-02-11 1974-12-31 Warner Lambert Co 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols
US4165374A (en) * 1976-02-09 1979-08-21 Sandoz Ltd. Thieno[3,2-c]pyridines
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
US4119718A (en) * 1977-05-02 1978-10-10 Merck & Co., Inc. 3-Amino-2-oxy-propoxy-substituted isothiazoles
FR2415622A1 (fr) * 1978-01-25 1979-08-24 Lipha Amino alcools derives de l'ortho-hydroxy cinnamate de methyle applicables notamment comme medicaments
US4202978A (en) * 1978-02-08 1980-05-13 Hoffmann-La Roche Inc. (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
JPS55124742A (en) * 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
SE8004087L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders

Also Published As

Publication number Publication date
DK335082A (da) 1982-07-27
RO85311A (ro) 1984-09-29
KR830007487A (ko) 1983-10-21
WO1982001869A1 (en) 1982-06-10
NZ198889A (en) 1985-08-16
PH18384A (en) 1985-06-19
AU546424B2 (en) 1985-08-29
EP0053435A1 (en) 1982-06-09
ZA817737B (en) 1983-07-27
EP0053435B1 (en) 1986-09-17
EG16108A (en) 1986-12-30
EP0065542B1 (en) 1986-07-23
AU7893881A (en) 1982-06-17
JPS57502123A (el) 1982-12-02
EP0065542A4 (en) 1983-04-25
DK164660C (da) 1992-12-14
IL64345A (en) 1986-02-28
CA1258868A (en) 1989-08-29
DK164660B (da) 1992-07-27
US4387103A (en) 1983-06-07
EP0065542A1 (en) 1982-12-01
KR880001539B1 (ko) 1988-08-20

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