FR2192812A1 - 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity - Google Patents
2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activityInfo
- Publication number
- FR2192812A1 FR2192812A1 FR7226159A FR7226159A FR2192812A1 FR 2192812 A1 FR2192812 A1 FR 2192812A1 FR 7226159 A FR7226159 A FR 7226159A FR 7226159 A FR7226159 A FR 7226159A FR 2192812 A1 FR2192812 A1 FR 2192812A1
- Authority
- FR
- France
- Prior art keywords
- local
- anaesth
- etic
- amino
- antitussive activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
Abstract
Title cpds. of formula: (where R1 is NH2 or the group OR where R is 1-4C alkyl; R2 and R3 are H or 1-4C alkyl, or R2 + R3 and the attached N-atom form a heterocyclic ring optically containing another heteroatom; X and Y are H, NO2 or halogen) their acid addn. and quaternary NH4 salts possess. Local anaesthetic activity similar to that of lignocaine hydrochloride. Unit doses of 20-250 mg of active component to a total of 20-2000 mg/day may be given.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7226159A FR2192812A1 (en) | 1972-07-20 | 1972-07-20 | 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7226159A FR2192812A1 (en) | 1972-07-20 | 1972-07-20 | 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2192812A1 true FR2192812A1 (en) | 1974-02-15 |
FR2192812B1 FR2192812B1 (en) | 1975-08-08 |
Family
ID=9102126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7226159A Granted FR2192812A1 (en) | 1972-07-20 | 1972-07-20 | 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2192812A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0053435A1 (en) * | 1980-11-28 | 1982-06-09 | American Hospital Supply Corporation | Compounds suitable for treatment or prophylaxis of cardiac disorders |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1236523B (en) * | 1962-02-15 | 1967-03-16 | Sanol Arznei Schwarz Gmbh | Process for the preparation of basic phenyl and naphthyl ethers and thioethers and their salts |
-
1972
- 1972-07-20 FR FR7226159A patent/FR2192812A1/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1236523B (en) * | 1962-02-15 | 1967-03-16 | Sanol Arznei Schwarz Gmbh | Process for the preparation of basic phenyl and naphthyl ethers and thioethers and their salts |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0053435A1 (en) * | 1980-11-28 | 1982-06-09 | American Hospital Supply Corporation | Compounds suitable for treatment or prophylaxis of cardiac disorders |
Also Published As
Publication number | Publication date |
---|---|
FR2192812B1 (en) | 1975-08-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |