FR2186238A1 - N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity - Google Patents

N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity

Info

Publication number
FR2186238A1
FR2186238A1 FR7216056A FR7216056A FR2186238A1 FR 2186238 A1 FR2186238 A1 FR 2186238A1 FR 7216056 A FR7216056 A FR 7216056A FR 7216056 A FR7216056 A FR 7216056A FR 2186238 A1 FR2186238 A1 FR 2186238A1
Authority
FR
France
Prior art keywords
alkyl
alkoxy
formula
acylhydrazides
hypotensive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7216056A
Other languages
French (fr)
Other versions
FR2186238B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferlux SA
Original Assignee
Ferlux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferlux SA filed Critical Ferlux SA
Priority to FR7216056A priority Critical patent/FR2186238A1/en
Publication of FR2186238A1 publication Critical patent/FR2186238A1/en
Application granted granted Critical
Publication of FR2186238B1 publication Critical patent/FR2186238B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Title cpds of formula (I): (where R is (i) (halo)alkyl, benyzl, styryl opt. substd. in the phenyl nucleus by >=1 halogen, NO2, alkoxy, heterocyclic gp. e.g. pyridyl, (ii) a gp. of formula (II): (X is O or S, R1, R2, R3 are H, halogen, alkyl or alkoxy, (iii) a gp. of formula (III): (R4-8 are H, halogen, alkyl, alkoxy, NO2; or R8 may be -NH. R9, R9 is H, alkyl), or (iv) a gp. of formula (IV): (n is 0, 1 or 2, R10-12 are H, alkyl, alkoxy, CF3, or R11, R12 may be two heteroatoms, e.g. O, joined to form a 5-membered ring, or R4 is a p-toluenesulphonamido gp.)). (I) are prepd. by reaction of ethyl esters with N'-2-imidaolinylhydrazines. Oral formulations may contain 100-200 mg of active component.
FR7216056A 1972-05-05 1972-05-05 N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity Granted FR2186238A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7216056A FR2186238A1 (en) 1972-05-05 1972-05-05 N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7216056A FR2186238A1 (en) 1972-05-05 1972-05-05 N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity

Publications (2)

Publication Number Publication Date
FR2186238A1 true FR2186238A1 (en) 1974-01-11
FR2186238B1 FR2186238B1 (en) 1975-06-20

Family

ID=9098058

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7216056A Granted FR2186238A1 (en) 1972-05-05 1972-05-05 N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity

Country Status (1)

Country Link
FR (1) FR2186238A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014205687A (en) * 2008-05-30 2014-10-30 株式会社アールテック・ウエノ Benzene or thiophen derivative and its use as vap-1 inhibitor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034500A1 (en) * 1969-01-28 1970-12-11 Lilly Co Eli

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034500A1 (en) * 1969-01-28 1970-12-11 Lilly Co Eli

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, VOL. 60, PAGE 464 1964 ) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014205687A (en) * 2008-05-30 2014-10-30 株式会社アールテック・ウエノ Benzene or thiophen derivative and its use as vap-1 inhibitor
US9603833B2 (en) 2008-05-30 2017-03-28 R-Tech Ueno, Ltd. Benzene or thiophene derivative and use thereof as VAP-1 inhibitor

Also Published As

Publication number Publication date
FR2186238B1 (en) 1975-06-20

Similar Documents

Publication Publication Date Title
DE69930926D1 (en) BENZOLSULFONAMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS
GB1222708A (en) Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
SE7508332L (en) METHOD OF PREPARING 3-QUINOLINE-CARBOXYLIC ACID DERIVATIVES AND USING IT AS A DRUG.
GB953427A (en) New oxazoline derivatives and method for the preparation thereof
FR2177511A1 (en) Quinolyl pipiridylethyl ketones - with vasodilatory and antispasmodic activity
FR2190430A1 (en) N-aminomethylhydroxamic acids - with antiinflammatory activity pre-pared by Mannich reaction
FR2186238A1 (en) N-2-imidazolinyl-N'-acylhydrazides - with analgesic hypotensive and cardiac stimulant activity
GB1061306A (en) 4-substituted-2-benzhydryl-2-butanol derivatives
GB1104145A (en) Pyrazolo-pyridine derivatives
GB994742A (en) Pharmaceutical tablets containing anthelmintics, and the manufacture thereof
GB1322451A (en) 3-amino-5-benzyl-1,2,4-oxadiazoles
ES424308A1 (en) N-(heteroaryl-methyl)-7{60 -acyl-6,14-(endoetheno or endoethano)-tetrahydro-nororipavines or-thebaines and salts thereof
BE799291A (en) 3-Amino-2-amino methyl-2-cyclohexen-1-ones - with analgesic antipyretic, CNS depressant activity
ES419044A1 (en) New derivatives of 1,4-benzodioxan, the preparation and the use thereof
GB1064132A (en) New quinoline derivatives, process for their production and use thereof in the production of carbostyril derivatives
ES378917A1 (en) Isoindoline and benzoisothiazoline derivatives, their preparation and pharmaceutical compositions containing them
FR2290203A1 (en) 10,11-DIHYDRO-3-CARBOXYCYPROHEPTADINE AND ITS N-OXIDE
ES369304A1 (en) IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES
FR2085651A1 (en) 4-(2-(p-chlorophenoxy)-2-methylpropionyloxymethyloxazolines - with hypolipaemic and hypocholesterolaemic activity
GB1098405A (en) New dibenzocycloheptadiene derivatives and their preparation
GB1330930A (en) Thiazole derivatives and a process for the manufacture thereof
FR2109279A5 (en) 4-alkyl (or cycloalkyl) benzoylmethyl anthranilates - - with spasmolytic, antiinflammatory and analgesic activity
GB1105007A (en) Nitrone derivatives and processes for preparation thereof
FR2211218A1 (en) Dibenzocyclooctaimidazoles - useful as anti inflammatories
FR2192812A1 (en) 2-(3-Amino 2-hydroxy propoxy) thymotic acid cpds - with local anaesth-etic, anti arrhythmic and antitussive activity

Legal Events

Date Code Title Description
ST Notification of lapse