SE7606424L - SUBSTITUTED BENZAMIDS - Google Patents
SUBSTITUTED BENZAMIDSInfo
- Publication number
- SE7606424L SE7606424L SE7606424A SE7606424A SE7606424L SE 7606424 L SE7606424 L SE 7606424L SE 7606424 A SE7606424 A SE 7606424A SE 7606424 A SE7606424 A SE 7606424A SE 7606424 L SE7606424 L SE 7606424L
- Authority
- SE
- Sweden
- Prior art keywords
- group
- alkyl
- alkoxy
- hydrogen
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Otolaryngology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1500105 Benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE 8 June 1976 [10 June 1975] 23695/76 Heading C2C Novel compounds (I) (including salts and oxides thereof) in which A is a hydrogen atom or a C 1-5 alkyl or 6 2-5 alkenyl group; X is a hydrogen atom or a C 1-5 alkoxy, C 1-5 alkyl, C 2-5 alkenyloxy or C 2-5 alkenyl group; Y is a hydrogen or halogen atom or a nitro, C 1-5 alkyl, C 1-5 alkoxy, amino or substituted amino group; Z is a hydrogen or halogen atom, a C 1-5 alkoxy or C 1-5 alkylsulphonyl group or a group of formula SO 2 NR 1 R 2 in which each of R 1 and R 2 , which may be the same or different, is a hydrogen atom or a C 1-5 alkyl group, or -NR 1 R 2 is a heterocyclic ring optionally containing another hetero atom; W is a C 1-4 straight or branched-chain alkylene group; B is a group of formula NR 3 R 4 in which R 3 is a C 1-5 alkyl group and R 4 is a C 1-5 hydroxyalkyl group; or B is a nitrogen-attached heterocyclic ring optionally containing a second nitrogen and optionally having a substituent; or B is a racemic, dextrorotary or laevorotary heterocyclic radical of Formula (IV) in which R is a C 1-5 alkyl group containing a reactive function and m is 1, 2 or 3, including the dextrorotatory and laevorotatory forms of the compounds, are made by interacting H 2 N-W-B and appropriate benzoic acids or derivatives thereof. Pharmaceutical preparations having antiemetic action contain (I) as active ingredient. Administration is parenterally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7518001A FR2313935A1 (en) | 1975-06-10 | 1975-06-10 | NEW BENZAMIDES SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION PROCESS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7606424L true SE7606424L (en) | 1976-12-11 |
| SE415971B SE415971B (en) | 1980-11-17 |
Family
ID=9156239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7606424A SE415971B (en) | 1975-06-10 | 1976-06-08 | SET TO MAKE SUBSTITUTED BENZAMIDS WITH THERAPEUTIC EFFECT |
Country Status (37)
| Country | Link |
|---|---|
| JP (1) | JPS6055503B2 (en) |
| AR (1) | AR210888A1 (en) |
| AT (1) | AT358571B (en) |
| AU (1) | AU506001B2 (en) |
| BE (1) | BE842059A (en) |
| BG (1) | BG27360A3 (en) |
| CA (1) | CA1064930A (en) |
| CH (1) | CH596175A5 (en) |
| CS (1) | CS189007B2 (en) |
| DD (1) | DD124380A5 (en) |
| DE (1) | DE2623075A1 (en) |
| DK (1) | DK255276A (en) |
| EG (1) | EG12285A (en) |
| ES (1) | ES448643A1 (en) |
| FI (1) | FI761669A (en) |
| FR (1) | FR2313935A1 (en) |
| GB (1) | GB1500105A (en) |
| HK (1) | HK46979A (en) |
| HU (1) | HU172195B (en) |
| IE (1) | IE43375B1 (en) |
| IN (1) | IN142899B (en) |
| LU (1) | LU75104A1 (en) |
| MW (1) | MW1676A1 (en) |
| MX (1) | MX3580E (en) |
| NL (1) | NL186382C (en) |
| NO (1) | NO146058C (en) |
| NZ (1) | NZ181072A (en) |
| OA (1) | OA05350A (en) |
| PH (1) | PH13912A (en) |
| PL (2) | PL103075B1 (en) |
| PT (1) | PT65164B (en) |
| RO (1) | RO70265A (en) |
| SE (1) | SE415971B (en) |
| SU (2) | SU607551A3 (en) |
| YU (1) | YU39352B (en) |
| ZA (1) | ZA763042B (en) |
| ZM (1) | ZM6576A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
| FR2415099A1 (en) * | 1978-01-20 | 1979-08-17 | Ile De France | NEW DERIVATIVES OF 4-AMINO-5-ALKYLSULFONYL ORTHO-ANISAMIDES, THEIR METHODS OF PREPARATION AND THEIR APPLICATION AS PSYCHOTROPES |
| FR2438650A1 (en) * | 1978-10-11 | 1980-05-09 | Ile De France | N- (1-METHYL 2-PYRROLIDINYL METHYL) 2,3-DIMETHOXY 5-METHYLSULFAMOYL BENZAMIDE AND DERIVATIVES THEREOF, THEIR PREPARATION METHODS AND THEIR APPLICATION IN THE TREATMENT OF LOWER URINARY DISORDERS |
| JPS597160A (en) * | 1982-06-28 | 1984-01-14 | ラボラトリーオス・デラグランヘ・エセ・ア | N-(1-propyl-2-pyrrolidinylmethyl)-2-methoxy-5- sulfamoylbenzamide, manufacture and antidepressive |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
| US5011992A (en) * | 1984-06-28 | 1991-04-30 | Bristol-Myers Squibb Company | Pharmacologically active substituted benzamides |
| US4820715A (en) * | 1984-06-28 | 1989-04-11 | Bristol-Myers Company | Anti-emetic quinuclidinyl benzamides |
| JP3026845B2 (en) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | Piperidine derivative |
| WO2014043707A1 (en) | 2012-09-17 | 2014-03-20 | Nektar Therapeutics | Oligomer-containing benzamide-based compounds |
-
1975
- 1975-06-10 FR FR7518001A patent/FR2313935A1/en active Granted
-
1976
- 1976-05-21 BE BE1007404A patent/BE842059A/en not_active IP Right Cessation
- 1976-05-21 ZA ZA763042A patent/ZA763042B/en unknown
- 1976-05-22 RO RO7686179A patent/RO70265A/en unknown
- 1976-05-22 DE DE19762623075 patent/DE2623075A1/en not_active Withdrawn
- 1976-05-24 AR AR263374A patent/AR210888A1/en active
- 1976-05-27 AU AU14360/76A patent/AU506001B2/en not_active Expired
- 1976-05-27 IN IN926/CAL/1976A patent/IN142899B/en unknown
- 1976-05-28 YU YU1318/76A patent/YU39352B/en unknown
- 1976-06-01 AT AT400176A patent/AT358571B/en not_active IP Right Cessation
- 1976-06-01 PT PT65164A patent/PT65164B/en unknown
- 1976-06-01 IE IE1166/76A patent/IE43375B1/en unknown
- 1976-06-02 EG EG326/76A patent/EG12285A/en active
- 1976-06-03 ZM ZM65/76A patent/ZM6576A1/en unknown
- 1976-06-04 CS CS763724A patent/CS189007B2/en unknown
- 1976-06-04 NZ NZ181072A patent/NZ181072A/en unknown
- 1976-06-04 BG BG033362A patent/BG27360A3/en unknown
- 1976-06-07 SU SU762362660A patent/SU607551A3/en active
- 1976-06-07 PH PH18542A patent/PH13912A/en unknown
- 1976-06-08 JP JP51067553A patent/JPS6055503B2/en not_active Expired
- 1976-06-08 ES ES448643A patent/ES448643A1/en not_active Expired
- 1976-06-08 SE SE7606424A patent/SE415971B/en not_active IP Right Cessation
- 1976-06-08 GB GB23695/76A patent/GB1500105A/en not_active Expired
- 1976-06-08 DD DD193235A patent/DD124380A5/xx not_active IP Right Cessation
- 1976-06-08 LU LU75104A patent/LU75104A1/xx unknown
- 1976-06-09 CA CA254,480A patent/CA1064930A/en not_active Expired
- 1976-06-09 DK DK255276A patent/DK255276A/en unknown
- 1976-06-09 PL PL1976190247A patent/PL103075B1/en not_active IP Right Cessation
- 1976-06-09 HU HU76SO00001171A patent/HU172195B/en unknown
- 1976-06-09 OA OA55847A patent/OA05350A/en unknown
- 1976-06-09 NO NO761977A patent/NO146058C/en unknown
- 1976-06-09 MX MX76291U patent/MX3580E/en unknown
- 1976-06-09 SU SU762366253A patent/SU645557A3/en active
- 1976-06-10 MW MW16/76A patent/MW1676A1/en unknown
- 1976-06-10 NL NLAANVRAGE7606284,A patent/NL186382C/en not_active IP Right Cessation
- 1976-06-10 CH CH736076A patent/CH596175A5/xx not_active IP Right Cessation
- 1976-06-10 PL PL1976190304A patent/PL102929B1/en unknown
- 1976-06-10 FI FI761669A patent/FI761669A/fi not_active Application Discontinuation
-
1979
- 1979-07-12 HK HK469/79A patent/HK46979A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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