GR3036741T3 - Biotherapeutic cell-coated microspheres. - Google Patents

Biotherapeutic cell-coated microspheres.

Info

Publication number
GR3036741T3
GR3036741T3 GR20010401598T GR20010401598T GR3036741T3 GR 3036741 T3 GR3036741 T3 GR 3036741T3 GR 20010401598 T GR20010401598 T GR 20010401598T GR 20010401598 T GR20010401598 T GR 20010401598T GR 3036741 T3 GR3036741 T3 GR 3036741T3
Authority
GR
Greece
Prior art keywords
pct
skin
cell
date nov
coated microspheres
Prior art date
Application number
GR20010401598T
Other languages
Greek (el)
English (en)
Inventor
David W Armstrong
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of GR3036741T3 publication Critical patent/GR3036741T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985—Skin or skin outgrowth, e.g. hair, nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR20010401598T 1992-05-18 2001-09-27 Biotherapeutic cell-coated microspheres. GR3036741T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929210574A GB9210574D0 (en) 1992-05-18 1992-05-18 Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
PCT/CA1993/000187 WO1993023088A1 (en) 1992-05-18 1993-04-23 Biotherapeutic cell-coated microspheres

Publications (1)

Publication Number Publication Date
GR3036741T3 true GR3036741T3 (en) 2001-12-31

Family

ID=10715656

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401598T GR3036741T3 (en) 1992-05-18 2001-09-27 Biotherapeutic cell-coated microspheres.

Country Status (16)

Country Link
US (1) US5830507A (enExample)
EP (1) EP0641223B1 (enExample)
JP (1) JP2820796B2 (enExample)
KR (1) KR950701533A (enExample)
AT (1) ATE203916T1 (enExample)
BR (1) BR9306375A (enExample)
CA (1) CA2135999C (enExample)
DE (1) DE69330562T2 (enExample)
DK (1) DK0641223T3 (enExample)
ES (1) ES2161229T3 (enExample)
GB (1) GB9210574D0 (enExample)
GR (1) GR3036741T3 (enExample)
NZ (1) NZ252661A (enExample)
PT (1) PT641223E (enExample)
RU (1) RU2104039C1 (enExample)
WO (1) WO1993023088A1 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654267A (en) * 1988-12-20 1997-08-05 La Jolla Cancer Research Center Cooperative combinations of ligands contained within a matrix
IL115728A0 (en) * 1994-10-25 1996-01-19 Boehringer Mannheim Gmbh Biomaterial containing epithelial cells and use thereof as a transplant
IL118376A0 (en) * 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US20020037566A1 (en) * 1997-04-16 2002-03-28 Rees Riley S. Cell-coated supports
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
AU1664299A (en) * 1997-10-25 1999-05-17 Roche Diagnostics Gmbh Autodegradable microcarriers and their use
CA2321829C (en) * 1998-03-07 2003-05-27 Daewoong Pharmaceutical Co., Ltd. Topical composition containing human epidermal growth factor
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
PT1071747E (pt) * 1998-04-17 2004-12-31 Nestle Sa Linhas celulares imortalizadas derivadas de tecidos cutaneos humanos normais
MXPA00010110A (es) * 1998-04-17 2002-08-06 Angiogenix Inc Factores angiogenicos terapeuticos y metodos para su uso.
ES2435847T3 (es) * 1998-10-23 2013-12-23 Polyheal Ltd. Composiciones de microesferas para curar heridas
RU2195889C2 (ru) * 1999-05-24 2003-01-10 Парамонов Борис Алексеевич Способ дермабразии
DE19937102A1 (de) * 1999-08-06 2001-02-15 Universitaetsklinikum Freiburg Gewebeersatz und Verfahren zu seiner Herstellung
US7056503B2 (en) * 1999-08-19 2006-06-06 Regents Of The University Of Michigan Enclosures housing cell-coated supports for treating tumors
DE19949290A1 (de) * 1999-10-12 2001-04-26 Albrecht Bettermann Partikuläres Konstrukt zur Verwendung in der Transplantationsmedizin
RU2184491C2 (ru) * 2000-03-10 2002-07-10 Озерская Ольга Сергеевна Способ устранения косметических дефектов кожного покрова
KR20010110945A (ko) 2000-06-09 2001-12-15 김정용 음경 확대 방법
RU2184492C2 (ru) * 2000-06-13 2002-07-10 Озерская Ольга Сергеевна Способ дерматохирургического лечения гипотрофических рубцов
US6719970B1 (en) * 2000-07-10 2004-04-13 Alkermes Controlled Therapeutics, Inc. Method of generating cartilage
US20030148924A1 (en) * 2002-07-09 2003-08-07 Tamar Tennenbaum Methods and pharmaceutical compositions of healing wounds
US20060258562A1 (en) * 2000-07-31 2006-11-16 Healor Ltd. Methods and pharmaceutical compositions for healing wounds
US20040037828A1 (en) * 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
US20100129332A1 (en) * 2000-07-31 2010-05-27 Tamar Tennenbaum Methods and pharmaceutical compositions for healing wounds
JP2002281964A (ja) * 2000-12-26 2002-10-02 Sanyo Chem Ind Ltd 細胞生産方法
AUPR289601A0 (en) * 2001-02-05 2001-03-01 Commonwealth Scientific And Industrial Research Organisation Method of tissue repair
RU2223790C2 (ru) * 2001-10-25 2004-02-20 ГФУН "Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена" Способ стерилизации биологических трансплантатов окисью этилена в жидкой среде
FR2839260B1 (fr) * 2002-05-03 2005-02-25 Inst Nat Sante Rech Med Microparticules a base d'un materiau bicompatible et biodegradable, supportant des cellules et des substances biologiquement actives
US20050129776A1 (en) 2002-05-03 2005-06-16 Inserm Microparticles supporting cells and active substances
US7402323B2 (en) * 2002-08-21 2008-07-22 Akpharma, Inc. Compositions and methods for treating skin conditions
RU2210389C1 (ru) * 2002-09-10 2003-08-20 Общество с ограниченной ответственностью "Мединтер Плюс" Спасательное покрывало
EP1635782A1 (de) * 2003-05-24 2006-03-22 JUVENA (International) AG Gewebekulturmedien als bestandteil von kosmetika
WO2005001073A1 (de) * 2003-06-23 2005-01-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur differenzierung von stammzellen in zellen, die ein pankreatisches hormon produzieren
NZ545318A (en) * 2003-07-15 2009-06-26 Univ Bar Ilan Pharmaceutical compositions for healing wounds comprising insulin and PKC alpha inhibitor
ZA200601089B (en) 2003-08-07 2007-05-30 Hearlor Ltd Pharmaceutical compositions and methods for accelerating wound healing
RU2240809C1 (ru) * 2003-08-26 2004-11-27 Государственное учреждение "Нижегородский научно-исследовательский институт травматологии и ортопедии" Способ получения бесклеточного дермального матрикса
WO2005037984A1 (ja) * 2003-10-20 2005-04-28 Jms Co., Ltd. 細胞取扱装置、組織再生用組成物及び組織再生方法
CA2625674C (en) 2005-08-29 2015-04-14 Healor Ltd. Methods and compositions for prevention and treatment of diabetic and aged skin
RU2316290C2 (ru) * 2005-11-21 2008-02-10 Институт биохимии им. А.Н. Баха РАН Сетчатый эндопротез для восстановительной хирургии
WO2008073614A2 (en) * 2006-11-02 2008-06-19 Akpharma Inc. Composition and method for enhancing skin cell growth, proliferation and repair
KR100805208B1 (ko) 2007-03-27 2008-02-21 주식회사 펩트론 엑센딘 함유 서방성 제제 조성물, 엑센딘 함유 서방성미립구 및 이의 제조 방법
US20100255070A1 (en) * 2007-05-22 2010-10-07 Prelief Inc. Compositions and methods for preventing, minimizing and healing skin irritation and trauma
EP2653166A3 (en) * 2007-07-30 2014-08-27 Healor Ltd. Pharmaceutical composition and related methods
WO2009043052A1 (en) * 2007-09-27 2009-04-02 Columbia University Methods and systems for forming biocompatible materials
WO2009086535A2 (en) * 2007-12-27 2009-07-09 The Trustees Of Columbia University In The City Of New York Systems and methods for forming patterned extracellular matrix materials
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
CN102066904B (zh) 2008-06-13 2015-07-15 株式会社资生堂 皮肤代替膜、模具以及皮肤外用剂的评价方法
EA014044B1 (ru) * 2008-07-09 2010-08-30 Общество С Ограниченной Ответственностью "Аква-Альянс" Наносомальная лекарственная форма препарата пролонгированного действия для лечения гепатита с (варианты)
US9708416B2 (en) * 2009-12-04 2017-07-18 Magle Ab Microspheres of hydrolysed starch with endogenous, charged ligands
WO2011083483A2 (en) 2010-01-11 2011-07-14 Healor Ltd. Method for treatment of inflammatory disease and disorder
JP5241764B2 (ja) * 2010-03-31 2013-07-17 テルモ株式会社 生体適合性材料の評価方法
RU2616866C1 (ru) * 2015-12-31 2017-04-18 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Биорезорбируемый микроноситель для доставки клеток в область заживления и регенерации ран
RU2658707C1 (ru) * 2016-12-28 2018-06-22 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
RU2644633C1 (ru) * 2016-12-28 2018-02-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
CN110960513A (zh) * 2019-11-29 2020-04-07 苏州瑞微生物科技有限公司 一种微球阵列及其制备方法和用途
CN113201481B (zh) * 2021-04-19 2023-10-13 清华大学深圳国际研究生院 皮肤微球及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461002A1 (fr) * 1979-07-13 1981-01-30 Inst Nat Sante Rech Med Procede pour stimuler la croissance des cellules d'epiderme humain et produits faisant application dudit procede
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
DE3688168T2 (de) * 1985-08-14 1993-10-28 Memorial Hospital Cancer Epidermiszellenextrakte und Verfahren zur Verbesserung der Wundheilung und zur Regenerierung der Epidermis.
FR2597499A1 (fr) * 1986-04-18 1987-10-23 Merieux Inst Procede de culture microbiologique sur supports de collagene, supports pour ce procede et produits obtenus
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf
US5015584A (en) * 1987-10-14 1991-05-14 Board Of Regents, The University Of Texas System Epidermal graft system
GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
CA1307225C (en) * 1988-07-19 1992-09-08 David W. Armstrong Cell culture bioreactor
US5135915A (en) * 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
JP3073766B2 (ja) * 1989-04-25 2000-08-07 チルドレンズ メディカル センター コーポレイション 重合マトリックス上の大容量の細胞の移植方法
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord

Also Published As

Publication number Publication date
BR9306375A (pt) 1997-03-04
PT641223E (pt) 2001-12-28
GB9210574D0 (en) 1992-07-01
DE69330562T2 (de) 2002-05-29
ES2161229T3 (es) 2001-12-01
CA2135999A1 (en) 1993-11-25
AU668959B2 (en) 1996-05-23
WO1993023088A1 (en) 1993-11-25
US5830507A (en) 1998-11-03
JPH07507063A (ja) 1995-08-03
KR950701533A (ko) 1995-04-28
EP0641223B1 (en) 2001-08-08
CA2135999C (en) 1999-07-13
RU94046192A (ru) 1996-10-10
ATE203916T1 (de) 2001-08-15
DE69330562D1 (de) 2001-09-13
NZ252661A (en) 1996-09-25
RU2104039C1 (ru) 1998-02-10
JP2820796B2 (ja) 1998-11-05
AU4257993A (en) 1993-12-13
EP0641223A1 (en) 1995-03-08
KR100381207B1 (enExample) 2003-10-23
DK0641223T3 (da) 2001-10-01

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