GR3035846T3 - Solid phase synthesis of oligoribonucleotide. - Google Patents

Solid phase synthesis of oligoribonucleotide.

Info

Publication number
GR3035846T3
GR3035846T3 GR20010400695T GR20010400695T GR3035846T3 GR 3035846 T3 GR3035846 T3 GR 3035846T3 GR 20010400695 T GR20010400695 T GR 20010400695T GR 20010400695 T GR20010400695 T GR 20010400695T GR 3035846 T3 GR3035846 T3 GR 3035846T3
Authority
GR
Greece
Prior art keywords
phase synthesis
oligoribonucleotide
solid phase
image
solid
Prior art date
Application number
GR20010400695T
Other languages
Greek (el)
English (en)
Inventor
Wolfgang Prof Pfleiderer
Ralf Dr Schnell
Stephan Dl Matysiak
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3035846T3 publication Critical patent/GR3035846T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
GR20010400695T 1993-12-17 2001-05-11 Solid phase synthesis of oligoribonucleotide. GR3035846T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4343126A DE4343126A1 (de) 1993-12-17 1993-12-17 Festphasensynthese von Oligoribonucleotiden

Publications (1)

Publication Number Publication Date
GR3035846T3 true GR3035846T3 (en) 2001-08-31

Family

ID=6505312

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400695T GR3035846T3 (en) 1993-12-17 2001-05-11 Solid phase synthesis of oligoribonucleotide.

Country Status (10)

Country Link
US (2) US5652358A (pt)
EP (1) EP0661291B1 (pt)
JP (1) JP3884492B2 (pt)
AT (1) ATE199560T1 (pt)
CA (1) CA2135039C (pt)
DE (2) DE4343126A1 (pt)
DK (1) DK0661291T3 (pt)
ES (1) ES2155460T3 (pt)
GR (1) GR3035846T3 (pt)
PT (1) PT661291E (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
GB9602025D0 (en) * 1996-02-01 1996-04-03 Amersham Int Plc Nucleoside analogues
GB2309968B (en) * 1996-02-01 2000-08-09 Amersham Int Plc Nucleoside analogues
AU2462497A (en) 1996-04-17 1997-11-19 Hubert Koster A combinatorial protecting group strategy for multifunctional molecules
DE19625397A1 (de) * 1996-06-25 1998-01-08 Deutsches Krebsforsch Verfahren zur Kombination von paralleler Oligonukleotidsynthese und Darstellung von Oligomer-Chips
US6133436A (en) * 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
DK0937096T3 (da) 1996-11-06 2004-06-14 Sequenom Inc Fremgangsmåde til massespektrometri-analyse
US7094943B2 (en) 1998-04-27 2006-08-22 Hubert Köster Solution phase biopolymer synthesis
AU2998800A (en) 1999-03-24 2000-10-09 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The N-acylphosphoramidites and their use in oligonucleotide synthesis
US7435390B2 (en) * 2001-01-26 2008-10-14 Third Wave Technologies, Inc. Nucleic acid synthesizers
US6932943B1 (en) 2001-01-26 2005-08-23 Third Wave Technologies Nucleic acid synthesizers
US20030072689A1 (en) * 2001-08-15 2003-04-17 Third Wave Technologies, Inc. Polymer synthesizer
US6632938B2 (en) * 2001-06-07 2003-10-14 Isis Pharmaceuticals, Inc. Processes of purifying oligonucleotides
AU2002353001A1 (en) * 2001-12-03 2003-06-17 The Government Of The United States Of America, Represented By The Secretary Of The Department Of He Thermolabile hydroxyl protecting groups and methods of use
BR0308118A (pt) * 2002-03-01 2005-01-11 Warner Lambert Co Método para o tratamento de osteoartrite
JP4580870B2 (ja) * 2003-09-02 2010-11-17 株式会社キラルジェン リボヌクレオチド又はリボヌクレオチド誘導体の製造方法
DE102004009977A1 (de) * 2004-03-01 2005-09-22 Chembiotech Gmbh Fluoreszierende Ethenonucleoside und Oligonucleotide mit hoher Stabilität
US9809824B2 (en) * 2004-12-13 2017-11-07 The United States Of America, Represented By The Secretary, Department Of Health And Human Services CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods
CA2606270A1 (en) * 2005-04-19 2006-10-26 Massachusetts Institute Of Technology Amphiphilic polymers and methods of use thereof
WO2007064291A1 (en) * 2005-11-30 2007-06-07 Jyoti Chattopadhyaya Method and compounds for rna synthesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2794461B2 (ja) * 1989-08-17 1998-09-03 有機合成薬品工業株式会社 ホスホアミダイト化合物及びそれを用いたオリゴリボヌクレオチドの固相合成法
JP2874128B2 (ja) * 1993-12-27 1999-03-24 株式会社神戸製鋼所 タイヤ試験機のリムクランプ装置

Also Published As

Publication number Publication date
JPH07196683A (ja) 1995-08-01
JP3884492B2 (ja) 2007-02-21
DK0661291T3 (da) 2001-07-16
ES2155460T3 (es) 2001-05-16
US5652358A (en) 1997-07-29
ATE199560T1 (de) 2001-03-15
EP0661291A1 (de) 1995-07-05
EP0661291B1 (de) 2001-03-07
DE4343126A1 (de) 1995-06-22
US5866700A (en) 1999-02-02
CA2135039A1 (en) 1995-06-18
PT661291E (pt) 2001-08-30
DE59409672D1 (de) 2001-04-12
CA2135039C (en) 2006-10-03

Similar Documents

Publication Publication Date Title
GR3035846T3 (en) Solid phase synthesis of oligoribonucleotide.
IL115790A0 (en) Pharmaceutical compositions containing boronic ester and acid compounds and methods for the preparation thereof
IL135562A0 (en) Process for the synthesis of 1,3-diols
MY115679A (en) Process for preparing intermediates to florfenicol
EP0638575A3 (de) Verfahren zur Herstellung von Diorganodialkoxysilanen.
EP0737314A4 (en) USES FOR GAL 4 RECEPTOR CONSTRUCTS
HU9402794D0 (en) Process for the preparation of 1,4-disubstituted-5(4h)-tetrazolinones
TW222289B (pt)
EP0569491A4 (en) 2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
BG103751A (en) Process for preparing pesticidal intermediates
EP0692476A3 (de) Verbessertes Verfahren zur Herstellung von N,N'-Carbonyldiazolen, insbesondere N,N'-Carbonyldiimidazol
ZA919184B (en) Heptamethyl indane compound
CA2258539A1 (en) Ring-fused dihydropyranes, process for the preparation and use thereof
IL110425A0 (en) Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines
ES2071873T3 (es) Procedimiento para la preparacion de compuestos de 1-oxa-3,8-diaza-4-oxo-espiro(4,5)decano.
EP0534449A3 (en) Process for the preparation of 3-aminomethyl-3,5,5-trialkylcyclohexylamine
ZA988397B (en) Process for the preparation of substituted 5,6-dihydro-2H-pyran-2-ones
TW239124B (en) Process for the preparation of 2,4,5-tribromopyrrole-3-carbonitrile
AU2732692A (en) Synthesis of 2,3,4,6-tetranitroaniline
GR3025179T3 (en) Alpha-aryl-alpha-hydroxy-beta-imidazolinylpropionamides
GB2275268B (en) Improved process for the preparation of 4,4-diaryl-3,1-benzoxazines
AU5549694A (en) Improved process for the synthesis of substituted 1,2,3-aminodiols
HU9603110D0 (en) Synthesis of 17beta-cyano-3-ethoxy-17alfa-hydroxy-6-methylandrosta-3,5,9(11)-triene
SI0973724T1 (en) Novel process for the preparation of (+/-)3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropan-1-ol or cericlamine (inn)
CA2207443A1 (en) Tricyclic compounds

Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees