GR3035082T3 - Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them. - Google Patents

Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
GR3035082T3
GR3035082T3 GR20000402769T GR20000402769T GR3035082T3 GR 3035082 T3 GR3035082 T3 GR 3035082T3 GR 20000402769 T GR20000402769 T GR 20000402769T GR 20000402769 T GR20000402769 T GR 20000402769T GR 3035082 T3 GR3035082 T3 GR 3035082T3
Authority
GR
Greece
Prior art keywords
substd
opt
phenyl
alkyl
preparation
Prior art date
Application number
GR20000402769T
Other languages
English (en)
Inventor
Gilbert Lavielle
Patrick Hautefaye
Olivier Muller
Mark Millan
Mauricette Brocco
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of GR3035082T3 publication Critical patent/GR3035082T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR20000402769T 1994-02-25 2000-12-15 Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them. GR3035082T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9402161A FR2716680B1 (fr) 1994-02-25 1994-02-25 Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
GR3035082T3 true GR3035082T3 (en) 2001-03-30

Family

ID=9460423

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000402769T GR3035082T3 (en) 1994-02-25 2000-12-15 Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them.

Country Status (18)

Country Link
US (1) US5500443A (el)
EP (1) EP0669331B1 (el)
JP (1) JP2959987B2 (el)
CN (1) CN1064964C (el)
AT (1) ATE196904T1 (el)
AU (1) AU681740B2 (el)
CA (1) CA2143252C (el)
DE (1) DE69519047T2 (el)
DK (1) DK0669331T3 (el)
ES (1) ES2153019T3 (el)
FI (1) FI950817A (el)
FR (1) FR2716680B1 (el)
GR (1) GR3035082T3 (el)
HK (1) HK1013291A1 (el)
NO (1) NO308604B1 (el)
NZ (1) NZ270565A (el)
PT (1) PT669331E (el)
ZA (1) ZA951576B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735129B1 (fr) * 1995-06-07 1997-07-11 Adir Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2762598A1 (fr) * 1997-04-25 1998-10-30 Adir Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent
FR2763335B1 (fr) * 1997-05-16 2000-11-24 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6960577B2 (en) * 1998-05-22 2005-11-01 Eli Lilly And Company Combination therapy for treatment of refractory depression
TWI226829B (en) * 1998-05-22 2005-01-21 Lilly Co Eli Pharmaceutical compositions for treatment of partial responders or refractory depression
CN101218223A (zh) * 2005-04-22 2008-07-09 惠氏公司 苯并二烷和苯并二氧戊环衍生物及其应用
US20090069267A1 (en) * 2006-01-17 2009-03-12 Abrams Daniel J Central administration of stable formulations of therapeutic agents for cns conditions
CL2007003044A1 (es) * 2006-10-24 2008-07-04 Wyeth Corp Compuestos derivados de benzoxazina; composicion farmaceutica que los comprende; y uso para el tratamiento de un trastorno psicotico, bipolar, depresivo y abuso o dependencia de sustancias entre otros.
AU2008279636A1 (en) * 2007-07-25 2009-01-29 The Regents Of The University Of Colorado Central administration of stable formulations of therapeutic agents for CNS conditions
CN102675302B (zh) * 2011-03-17 2014-06-11 南京大学 含1,4-苯并二噁烷的噻二唑衍生物及其制法与其抗菌活性
CN102690261B (zh) * 2011-03-25 2015-02-25 南京大学 含1,4-苯并二噁烷的1,3,4-噁二唑衍生物的制法及其在抗癌药物中应用
CN102746286B (zh) * 2012-07-25 2015-07-15 山东理工大学 苯并二噁唑及其制备方法
CN104327065A (zh) * 2014-09-15 2015-02-04 湖南华腾制药有限公司 一种n-甲基-(喹啉-4-基)甲烷胺的制备方法
CN104311547A (zh) * 2014-09-15 2015-01-28 湖南华腾制药有限公司 一种噻唑衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124598A (en) * 1962-10-02 1964-03-10 Aminoalkoxy substituted benzodioxanes
US3345364A (en) * 1964-05-06 1967-10-03 Janssen Pharmaceutica Nv Benzimidazolinyl piperidines
FR2644786B1 (fr) * 1989-03-21 1993-12-31 Adir Cie Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
JPH03264528A (ja) * 1990-03-14 1991-11-25 Mitsubishi Kasei Corp 抗不安薬

Also Published As

Publication number Publication date
DE69519047T2 (de) 2001-05-10
FI950817A (fi) 1995-08-26
CN1064964C (zh) 2001-04-25
NO308604B1 (no) 2000-10-02
ATE196904T1 (de) 2000-10-15
DK0669331T3 (da) 2001-02-12
EP0669331A1 (fr) 1995-08-30
FR2716680A1 (fr) 1995-09-01
AU1344895A (en) 1995-09-07
EP0669331B1 (fr) 2000-10-11
PT669331E (pt) 2001-01-31
ES2153019T3 (es) 2001-02-16
FR2716680B1 (fr) 1996-04-05
CA2143252C (fr) 2002-04-16
ZA951576B (en) 1995-12-12
CA2143252A1 (fr) 1995-08-26
DE69519047D1 (de) 2000-11-16
FI950817A0 (fi) 1995-02-22
CN1120041A (zh) 1996-04-10
JP2959987B2 (ja) 1999-10-06
US5500443A (en) 1996-03-19
JPH0841046A (ja) 1996-02-13
NO950712L (no) 1995-08-28
AU681740B2 (en) 1997-09-04
NZ270565A (en) 1995-12-21
HK1013291A1 (en) 1999-08-20
NO950712D0 (no) 1995-02-24

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Legal Events

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